Circularly polarized lasing over wide wavelength range in spin-controlled (1 1 0) vertical-cavity surface-emitting laser

We investigated the emission wavelength dependence of the lasing polarization in a (1 1 0)-oriented vertical-cavity surface-emitting laser (VCSEL) with GaAs/AlGaAs quantum wells under optical spin injection at room temperature. Lasing was observed in the one circularly polarized mode over a wide wavelength range from 838 to 857 nm, in which a degree of circular polarization higher than 0.8 was maintained. The optical gain spectrum that contributed to the circularly polarized lasing is discussed based on the optical selection rules and the measured polarization-resolved photoluminescence spectra of the active layers.     

Simple synthesis of β-trifluoromethylstyrenes using (E)-trimethyl-(3,3,3-trifluoroprop-1-enyl)silane

(E)-trimethyl-(3,3,3-trifluoroprop-1-enyl)silane (1) was synthesized as a reagent for use in Hiyama cross-coupling reactions for the production of β-trifluoromethylstyrene derivatives. Cross-coupling of 1 with electronically diverse aryl iodides was achieved by treatment with CsF in the presence of catalytic amounts of palladium to afford the desired products in moderate to good yields.     

Single-step thioetherification by indium-catalyzed reductive coupling of carboxylic acids with thiols

Direct thioetherification from a variety of aromatic carboxylic acids and thiols using a reducing system combined with InBr(3) and 1,1,3,3-teramethyldisiloxane (TMDS) in a one-pot procedure is demonstrated. It was also found that a system combined with InI(3) and TMDS underwent thioetherification of aliphatic carboxylic acids with thiols.     

Visualization of dynamic change in contraction-induced lipid composition in mouse skeletal muscle by matrix-assisted laser desorption/ionization imaging mass spectrometry

Lipids in skeletal muscle play a fundamental role both in normal muscle metabolism and in disease states. Skeletal muscle lipid accumulation is associated with several chronic metabolic disorders, including obesity, insulin resistance, and type 2 diabetes. However, it is poorly understood whether the lipid composition of skeletal muscle changes by contraction, due to the complexity of lipid molecular species. In this study, we used matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) to investigate changes in skeletal muscle lipid composition induced by contraction. We successfully observed the reduction of diacylglycerol and triacylglycerol, which are generally associated with muscle contraction. Interestingly, we found the accumulation of some saturated and mono-unsaturated fatty acids and poly-unsaturated fatty acids containing phosphatidylcholine in contracted muscles. Moreover, the distributions of several types of lipid were changed by contraction. Our results show that changes in the lipid amount, lipid composition, and energy metabolic activity can be evaluated in each local spot of cells and tissues at the same time using MALDI-IMS. In conclusion, MALDI-IMS is a powerful tool for studying lipid changes associated with contractions.     

Development and validation of a GC-EI-MS method with reduced adsorption loss for the quantification of olanzapine in human plasma

A simple and sensitive GC-EI-MS method using solvent extraction and evaporation was developed for the determination of olanzapine concentrations in plasma samples. Because olanzapine and promazine, which was used as the internal standard (IS), are nitrogenous bases, they can adsorb to the weakly acidic silanol groups on the surfaces of glass centrifuge tubes during solvent extraction and evaporation. Silylation of the glass tubes, addition of triethylamine (TEA), and use of a sample solution with a basic pH could prevent adsorption loss. The extraction method involved mixing plasma (500 μL) in a silylated glass tube with a promazine solution (2 μg/mL, 25 μL) in methanol containing 1% TEA. After addition of aqueous sodium carbonate (0.5 mol/L, pH 11.1, 1 mL) and extraction into 3 mL of dichloromethane/n-hexane (1:1, v/v) containing 1% TEA, the organic phase was evaporated to dryness in a silylated glass tube. The residue was dissolved in ethyl acetate containing 1% TEA (50 μL). For GC-EI-MS analysis, the calibration curves of olanzapine in human plasma were linear from 0.5 to 100 ng/mL. Intra- and interday precisions in plasma were both less than 7.36% (coefficient of variation), and the accuracy was between 94.6 and 110% for solutions with concentrations greater than 0.5 ng/mL. The limit of quantification was 0.5 ng/mL in plasma. The assay was applied to therapeutic drug monitoring in samples from three schizophrenic patients.     

Experimental detection of domain wall propagation above the Walker field

The domain wall (DW) velocity above the Walker field drops abruptly with increasing magnetic field, because of the so-called Walker breakdown, where the DW moves with a precessional mode. On applying the higher field, the DW velocity again starts to increase gradually. We report the DW propagation around this local minimum regime in detail, investigated through the time-resolved electrical detection technique, with a magnetic tunnel junction. Just above the Walker field, we succeeded in detecting the precessional motion of the DW in a real-time regime, while a different mode appeared around the local minimum of the DW velocity.     

Modified scattering operator for the Hartree-Fock equation

We study the scattering problem for the Hartree-Fock equation

(HRF)     

Direct simulations of trailing-edge noise generation from two-dimensional airfoils at low Reynolds numbers

The aeroacoustic sound generated from the flow around two NACA four-digit airfoils is investigated numerically, at relatively low Reynolds numbers that do not prompt boundary-layer transition. By using high-order finite-difference schemes to discretize compressible Navier–Stokes equations, the sound scattered on airfoil surface is directly resolved as an unsteady pressure fluctuation. As the wavelength of an emitted noise is shortened compared to the airfoil chord, the diffraction effect on non-compact chord length appears more noticeable, developing multiple lobes in directivity. The instability mechanism that produces sound sources, or unsteady vortical motions, is quantitatively examined, also by using a linear stability theory. While the evidence of boundary-layer instability waves is captured in the present result, the most amplified frequency in the boundary shear layer does not necessarily agree with the primary frequency of a trailing-edge noise, when wake instability is dominant in laminar flow. This contradicts the observation of other trailing-edge noise studies at higher Reynolds numbers. However, via acoustic disturbances, the boundary-layer instability may become more significant, through the resonance with the wake instability, excited by increasing a base-flow Mach number. Evidence suggests that this would correspond to the onset of an acoustic feedback loop. The wake-flow frequencies derived by an absolute-instability analysis are compared with the frequencies realized in flow simulations, to clarify the effect of an acoustic feedback mechanism, at a low Reynolds number.     

Time-reversal characteristics of quantum normal diffusion: time-continuous models

In quantum map systems exhibiting normal diffusion, time-reversal characteristics converge to a universal scaling behavior which implies a prototype of irreversible quantum process [H.S. Yamada, K.S. Ikeda, Eur. Phys. J. B 85, 41 (2012)]. In the present paper, we extend the investigation of time-reversal characteristic to time-continuous quantum systems which show normal diffusion. Typical four representative models are examined, which is either deterministic or stochastic, and either has or not has the classical counterpart. Extensive numerical examinations demonstrate that three of the four models have the time-reversal characteristics obeying the same universal limit as the quantum map systems. The only nontrivial counterexample is the critical Harper model, whose time-reversal characteristics significantly deviates from the universal curve. In the critical Harper model modulated by a weak noise that does not change the original diffusion constant, time-reversal characteristic recovers the universal behavior.