Indium-mediated consecutive 1,2-shift reaction and regioselective allylation of vinyl epoxides

Allyl indium, prepared from allyl bromide and indium metal in aprotic solvent, reacts with terminal vinyl epoxides at room temperature to afford various bishomoallyl alcohols in moderate to high yields via consecutive 1,2-shift reaction and regioselective allylation.     

活性炭的表面化学改性及其对有机硫化物的吸附性能的研究

活性炭； 表面化学改性； 有机硫化物； 吸附性     

Synthesis and anti-HBV evaluation of mono L-amino acid ester,mono non-steroid anti-inflammation drug carboxylic ester derivatives of acyclonucleoside phosphonates简

A series of mono L-amino acid ester, mono non-steroid anti-inflammation drug(NSAID), carboxylic ester derivatives of acyclonucleoside phosphonates were prepared by using a ‘‘one pot synthesis' ' method and their in vitro anti-HBV activity were evaluated in HepG 2.2.15 cells. Compound 9a exhibited more potent anti-HBV activity and lower cytotoxicity than those of adefovir dipivoxil with IC50 and selective index(SI) values of 0.48 mmol/L and 763.72, respectively.     

Hydrogen-Bond Structure and Dynamics of TADDOL Asymmetric Organocatalysts Correlate with Catalytic Activity

The catalytic efficiency of diol-based organocatalysts has been shown to strongly depend on the diols molecular structure including hydrogen-bonding, yet, the underlying molecular-level origins have remained elusive. Herein a study on the inter- and intramolecular hydrogen-bonding of two isomeric diol-based catalysts (TADDOLs) in solution is presented: 1-Naphthyl substituted TADDOL (1nTADDOL), which exhibits high catalytic efficiency, and 2-naphthyl substituted TADDOL (2nTADDOL), which is a poor catalyst. Using nuclear magnetic resonance and infrared spectroscopy, comparable hydrogen-bond strengths for both TADDOLs in solution were found, however, significantly slower bonding dynamics for 1nTADDOL. In aromatic solvents, 1nTADDOL forms less, but longer-lived, intermolecular OH⋅⋅⋅π bonds to solvent molecules, as compared to 2nTADDOL. Thus, rather than previously suggested differences in intermolecular hydrogen-bonding strengths, the results suggest that the hydrogen-bonding kinetics and entropies differ for both TADDOLs, which also explains their vastly different catalytic activities.     

Time-resolved imaging of VUV emission from a He-Xe micro surfacedischarge

A direct observation of two-dimensional, time dependent behavior of 147 nm and 173 nm vacuum ultra violet emission from a single surface discharge type AC plasma display panel cell were obtained using a gated, image intensified charge-coupled device (ICCD). The images on the ICCD are formed by a pinhole. The two lines show similar spatial profile but quite different temporal behavior     

Consensus protocol design for discrete‐time networks of multiagent with time‐varying delay via logarithmic quantizer

This article considers the problem of consensus for discrete‐time networks of multiagent with time‐varying delays and quantization. It is assumed that the logarithmic quantizer is utilized between the information flow through the sensor of each agent, and its quantization error is included in the proposed method. By constructing a suitable Lyapunov‐Krasovskii functional and utilizing matrix theory, a new consensus criterion for the concerned systems is established in terms of linear matrix inequalities (LMIs) which can be easily solved by various effective optimization algorithms. Based on the consensus criterion, a designing method of consensus protocol is introduced. One numerical example is given to illustrate the effectiveness of the proposed method. © 2014 Wiley Periodicals, Inc. Complexity 21: 163–176, 2015     

Analysis of fatty acids in lung tissues using gas chromatography-mass spectrometry preceded by derivatization-solid-phase microextraction with a novel fiber

In this article, a laboratory-made sol-gel derived fiber with butyl methacrylate/hydroxy-terminated silicone oil (BMA/OH-TSO) coating was first used for headspace solid-phase microextraction (HS-SPME) of medium and long chain fatty acids after derivatization and applied to the analysis of fatty acids in lung tissues by coupling to gas chromatography-mass spectrometry (GC-MS). The experimental parameters for derivatization, HS-SPME and desorption were optimized. Fatty acids in cancerous lung tissues from five patients with lung cancer were determined under the optimized conditions. Normal lung tissues from the same five patients were used as controls. This fiber showed higher extraction efficiency for fatty acids after derivatization when compared with commercial polydimethylsiloxane (PDMS) and polydimethylsiloxane-divinylbenzene (PDMS/DVB) fibers due to the three-dimensional network in the coating. The method presented in this paper showed satisfactory precision, accuracy, linearity and limits of detection (LODs). The relative standard deviation values were below 13.3% (n = 5) and the recoveries obtained ranged from 76.35% to 107.0%. The results obtained using the SPME method were also compared with those got by using liquid-liquid extraction (LLE) technique. It was found that the sensitivity could be enhanced by the SPME method. The analysis of the cancerous lung tissues and normal controls from five patients with lung cancer indicated that the main components of lung tissue were palmitic acid (C_16:0), stearic acid (C_18:0) and lignoceric acid (C_24:0). A comparison between the levels of the fatty acids in cancerous lung tissues and normal controls from the same a patient with lung cancer shows that most of the saturated fatty acids showed higher levels in cancerous lung tissues, while unsaturated fatty acids showed higher levels in normal controls on the whole.