Electroactive Composite of FeCl3‐Doped P3HT/PLGA with Adjustable Electrical Conductivity for Potential Application in Neural Tissue Engineering

Conducting polymers (CPs) is one of intelligent biomaterials with the specific properties of reversible redox states, which have a significant effects on the cell behaviors and nerve tissue regeneration. However, the effects of CPs with different electrical conductivity on the behaviors of nerve cells are rarely reported. Therefore, a kind of Poly(3‐hexylthiophene) (P3HT) with certain molecular weight is synthesized by Kumada catalyst transfer polymerization (KCTP) method and employed to prepare bioabsorbable and electroactive intelligent composites of Poly(3‐hexylthiophene)/Poly(glycolide‐lactide) (P3HT/PLGA). FeCl₃ doping electroactive membranes with different electrical conductivities are prepared to investigate the cell behaviors. On the substrate with higher electrical conductivity, the proliferation of rat adrenal pheochromocytoma cells (PC12 cells) is significantly promoted and neurite length is increased obviously. In particular, the most significant improvements are the neuron gene expression of Synapsin 1 and microtubule‐associated protein 2 (MAP2) by the composites with high conductivity. These results suggest that P3HT/PLGA with suitable electrical conductivity have a positive role in promoting neural growth and differentiation, which is promising for advancing potential application of nerve repair and regeneration.     

Engineering of Portable Smartphone Integrated with Liposome-Encapsulated Curcumin for Onsite Visual Ratiometric Fluorescence Imaging of Hypochlorite

Precisely onsite monitoring of hypochlorite (ClO⁻) is of great significance to guide its rational use, reducing/avoiding its potential threat toward food safety and human health. Considering ClO⁻ could quench fluorescence of curcumin (CCM) by oxidizing the o-methoxyphenol of CCM into benzoquinone, a portable ratiometric fluorescence sensor integrated with smartphone was designed for realizing the visual point-of-care testing (POCT) of ClO⁻. The amphiphilic phospholipid polymer was used as carrier to wrap curcumin, forming a novel liposome-encapsulated CCM, which provided a scaffold to bind with [Ru(bpy)₃]²⁺ through electrostatic interaction, thus assembling [Ru(bpy)₃]²⁺-functionalized liposome-encapsulated CCM ([Ru(bpy)₃]²⁺@CCM-NPs). Further integrated with smartphone, visual imaging of [Ru(bpy)₃]²⁺@CCM-NPs could be achieved and the accurate onsite detection of ClO⁻ could be realized with a detection limit of 66.31 nM and a linear range of 0.2210 to 80.0 μM. In addition, the sensor could monitor ClO⁻ in real samples with an onsite detection time of ∼154.0 s.     

Facile synthesis of ABCDE‐type H‐shaped quintopolymers by combination of ATRP,ROP, and click chemistry and their potential applications as drug carriers

A facile approach to synthesis of ABCDE‐type H‐shaped quintopolymer comprising polystyrene (PSt, C) main chain and poly(ethylene glycol) (PEG, A), poly(ε‐caprolactone) (PCL, B), poly(L ‐lactide) (PLLA, D), and poly(acrylic acid) (PAA, E) side chains was described, and physicochemical properties and potential applications as drug carriers of copolymers obtained were investigated. Azide‐alkyne cycloaddition reaction and hydrolysis were used to synthesize well‐defined H‐shaped quintopolymer. Cytotoxicity studies revealed H‐shaped copolymer aggregates were nontoxic and biocompatible, and drug loading and release properties were affected by macromolecular architecture, chemical composition, and pH value. The release rate of doxorubicin from copolymer aggregates at pH 7.4 was decreased in the order PAA‐b‐PLLA > H‐shaped copolymer > PEG‐PCL‐PSt star, and the release kinetics at lower pH was faster. The H‐shaped copolymer aggregates have a potential as controlled delivery vehicles due to their excellent storage stability, satisfactory drug loading capacity, and pH‐sensitive release rate of doxorubicin. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012     

Laser-diode-pumped zigzag slab Nd:YAG master oscillator power amplifier

A high-repetition rate master oscillator power amplifier pumped with laser diodes (LDs) is reported. An injection seeding single-frequency electro-optical Q-switched Nd:YAG laser is used as an oscillator, and a conductively cooled Nd:YAG zigzag slab with a bounce-pumped architecture is utilized as a power amplifier. Pulse energies of over 800 mJ at 1 064 nm and 400 mJ at 532 nm, corresponding to average powers of 200 and 100 W, respectively, are achieved with a 12.6-ns pulse width at 250 Hz. Output frequency fluctuations and single-frequency operation are further monitored. Experimental results reveal that the proposed system, which features a single-pass amplified configuration, is a promising design for space-based applications.     

圆偏振发光性质的热活化延迟荧光材料及电致发光器件

具有圆偏振发光性质的热活化延迟荧光(circularly polarized thermally activated delayed fluorescence,CP-TADF)材料,因其在数据存储、生物成像以及3D显示等领域的应用前景,受到学者们的广泛关注。基于此类材料所制备的圆偏振热活化延迟荧光器件展现出优异的器件性能。本文从圆偏振热活化延迟荧光材料的发光机理及分子设计策略出发,依据CP-TADF材料构筑方法的不同,概括了其结构设计策略,系统地综述了各种类型CP-TADF材料的分子结构和光电性能的关系及其在电致发光器件领域的应用,最后探讨了目前CP-TADF材料存在的问题,并展望了其未来发展前景及挑战。     

芳基硅磷光主体材料在有机电致发光器件中的应用

有机电致发光器件(organic light emitting diodes, OLEDs)在固态照明和平板显示等领域显现出巨大的商业应用前景,近年来受到人们的广泛关注。由于芳基硅基团的易修饰性和多功能性,可以通过连接结构不同的功能单元构建性能优异的主体材料,以此来实现高效的有机电致发光器件,因此近年来芳基硅基团在合成高性能电致发光主体材料方面获得了广泛的研究和关注。本文从材料的设计分类出发,综述了芳基硅主体材料的研究现状,对其分子结构特征、热力学性质、光物理性能、电化学性质及电致发光器件性能等做了详细的归纳总结,讨论了芳基硅主体材料在有机电致发光器件方面存在的不足,并展望了其应用前景和发展方向。     

Hochschild Cohomology Rings of Temperley-Lieb Algebras

The authors first construct an explicit minimal projective bimodule resolution(P, δ) of the Temperley-Lieb algebra A, and then apply it to calculate the Hochschild cohomology groups and the cup product of the Hochschild cohomology ring of A based on a comultiplicative map Δ:P → PAP. As a consequence, the authors determine the multiplicative structure of Hochschild cohomology rings of both Temperley-Lieb algebras and representation-finite q-Schur algebras under the cup product by giving an explicit presentation by generators and relations.     

Fluorine-induced aggregate-interlocking for color-tunable organic afterglow with a simultaneously improved efficiency and lifetime

Designing organic afterglow materials with a high efficiency and long lifetime is highly attractive but challenging because of the inherent competition between the luminescence efficiency and lifetime. Here, we propose a simple yet efficient strategy, namely fluorine-induced aggregate-interlocking (FIAI), to realize both an enhanced efficiency and elongated lifetime of afterglow materials by stimulating the synergistic effects of the introduced fluorine atoms to efficiently promote intersystem crossing (ISC) and intermolecular non-covalent interactions for facilitating both the generation of triplet excitons and suppression of non-radiative decays. Thus, the fluorine-incorporated afterglow molecules exhibit greatly enhanced ISC with a rate constant up to 5.84 × 10⁷ s⁻¹ and suppressed non-radiative decay down to 0.89 s⁻¹, resulting in efficient organic afterglow with a simultaneously improved efficiency up to 10.5% and a lifetime of 1.09 s. Moreover, accompanied by the efficient phosphorescence emission especially at cryogenic temperature, color-tunable afterglow was also observed at different temperatures. Therefore, tri-mode multiplexing encryption devices by combining lifetime, temperature and color, and visual temperature sensing were successfully established. The FIAI strategy by addressing fundamental issues of afterglow emission paves the way to develop high-performance organic afterglow materials, opening up a broad prospect of aggregated and excited state tuning of organic solids for emission lifetime-resolved applications.

Through the fluorine-induced aggregate-interlocking (FIAI) strategy, the designed afterglow materials showed both improved quantum yields and prolonged lifetimes by breaking through the intrinsic bottlenecks of organic afterglow.