Sensitivity and correlation analysis of the physical parameters in absorption,four-wave mixing,and Schlieren experiments

Experimental data that are used to determine rate coefficients depend not only upon reaction rates but also the physical properties of the measured species. Sensitivity coefficients are presented for the physical parameters of three general experimental techniques: a signal linearly dependent on the concentration of a species, a signal quadratically dependent on concentration, and a schlieren signal, which depends upon a bulk property of the system. With these, both the physical and chemical parameters of a model may be treated on a comparable basis. The similarities and differences between these techniques are illustrated in a simple example of radical formation via first-order precursor decomposition followed by second-order recombination. The results are then applied to two important examples: H₂ + O₂ and CH₃ + CH₃. In almost all cases, the experimental data contains more information about the physical parameters, such as the optical cross section, than the kinetic rate coefficients. Furthermore, if a physical parameter is not properly treated; strong correlations between it and rate coefficients will introduce significant systematic biases in the rate coefficient. © 1995 John Wiley & Sons, Inc.     

<Emphasis Type="Italic">Z</Emphasis><Superscript>0</Superscript>-tagged quark jets at the large hadron collider

The Large Hadron Collider will allow studies of hard probes in nucleus-nucleus collisions which were not accessible at the Relativistic Heavy Ion Collider—even the study of small cross-section Z ⁰-tagged jets becomes possible. Going beyond the measurement of back-to-back correlations of two strongly interacting particles to measure plasma properties, we replace one side by an electromagnetic probe which propagates through the plasma undisturbed and therefore provides a measurement of the energy of the initial hard scattering. We show that at sufficiently high transverse momentum the Z ⁰-tagged jets originate predominately from the fragmentation of quarks and anti-quarks while gluon jets are suppressed. We propose to use lepton-pair tagged jets to study medium-induced partonic energy loss and to measure in-medium parton fragmentation functions to determine the opacity of the quark gluon plasma.     

Deactivation on the Nd3+, 4F32 level in neodymium chloride - aluminum chloride vapor complexes

The first fluorescence lifetime studies in a trivalent rare earth-metal vapor complex NdCl₃ · (AlCl₃)_χ are reported. The observed, temperature-dependent, nonradiative deactivation and the inferred radiative lifetime are discussed in terms of various models. At 803 K, corresponding to a density of 4.6 × 10¹⁷ Nd³⁺ ions/cm³ and a total system pressure ≈5 atm, the measured lifetime is 46 μs.     

Generation of GW radiation pulses from a VUV free-electron laser operating in the femtosecond regime

Experimental results are presented from vacuum-ultraviolet free-electron laser (FEL) operating in the self-amplified spontaneous emission (SASE) mode. The generation of ultrashort radiation pulses became possible due to specific tailoring of the bunch charge distribution. A complete characterization of the linear and nonlinear modes of the SASE FEL operation was performed. At saturation the FEL produces ultrashort pulses (30-100 fs FWHM) with a peak radiation power in the GW level and with full transverse coherence. The wavelength was tuned in the range of 95-105 nm.     

A Combination of Spin Diffusion Methods for the Determination of Protein–Ligand Complex Structural Ensembles

Structure‐based drug design (SBDD) is a powerful and widely used approach to optimize affinity of drug candidates. With the recently introduced INPHARMA method, the binding mode of small molecules to their protein target can be characterized even if no spectroscopic information about the protein is known. Here, we show that the combination of the spin‐diffusion‐based NMR methods INPHARMA, trNOE, and STD results in an accurate scoring function for docking modes and therefore determination of protein–ligand complex structures. Applications are shown on the model system protein kinase A and the drug targets glycogen phosphorylase and soluble epoxide hydrolase (sEH). Multiplexing of several ligands improves the reliability of the scoring function further. The new score allows in the case of sEH detecting two binding modes of the ligand in its binding site, which was corroborated by X‐ray analysis.     

A [2+2+2]‐Cyclotrimerization Approach to Selectively Substituted Fluorenes and Fluorenols,and Their Conversion to 9,9′‐Spirobifluorenes

Synthesis of selectively substituted fluorenes and fluorenols was achieved by using catalytic [2+2+2]cyclotrimerization. Various starting diynes were reacted with different alkynes in the presence of a catalytic amount of Wilkinson’s catalyst (RhCl(PPh₃)₃) providing the compounds possessing the fluorene scaffold in good isolated yields. A set of four regioselectively substituted fluorenols was converted to the corresponding 9,9′‐spirobifluorenes and their spectral characteristics were measured.     

Solitary wave solutions to nonlinear evolution equations in mathematical physics

This paper obtains solitons as well as other solutions to a few nonlinear evolution equations that appear in various areas of mathematical physics. The two analytical integrators that are applied to extract solutions are tan–cot method and functional variable approaches. The soliton solutions can be used in the further study of shallow water waves in (1+1) as well as (2+1) dimensions.