全文获取类型
收费全文 | 583篇 |
免费 | 13篇 |
国内免费 | 3篇 |
专业分类
化学 | 400篇 |
晶体学 | 7篇 |
力学 | 3篇 |
数学 | 67篇 |
物理学 | 122篇 |
出版年
2023年 | 4篇 |
2022年 | 4篇 |
2021年 | 9篇 |
2020年 | 11篇 |
2019年 | 11篇 |
2018年 | 6篇 |
2017年 | 5篇 |
2016年 | 16篇 |
2015年 | 11篇 |
2014年 | 15篇 |
2013年 | 39篇 |
2012年 | 23篇 |
2011年 | 32篇 |
2010年 | 22篇 |
2009年 | 15篇 |
2008年 | 34篇 |
2007年 | 32篇 |
2006年 | 33篇 |
2005年 | 25篇 |
2004年 | 23篇 |
2003年 | 20篇 |
2002年 | 15篇 |
2001年 | 6篇 |
2000年 | 15篇 |
1999年 | 9篇 |
1998年 | 4篇 |
1997年 | 5篇 |
1996年 | 10篇 |
1995年 | 11篇 |
1994年 | 10篇 |
1993年 | 9篇 |
1992年 | 13篇 |
1991年 | 4篇 |
1990年 | 7篇 |
1989年 | 9篇 |
1988年 | 10篇 |
1987年 | 18篇 |
1986年 | 5篇 |
1985年 | 8篇 |
1984年 | 4篇 |
1983年 | 5篇 |
1982年 | 3篇 |
1981年 | 4篇 |
1980年 | 3篇 |
1979年 | 4篇 |
1978年 | 4篇 |
1977年 | 5篇 |
1975年 | 4篇 |
1957年 | 1篇 |
1917年 | 1篇 |
排序方式: 共有599条查询结果,搜索用时 468 毫秒
61.
62.
V. Hernandez Perez B.J. Azzopardi R. Kaji M.J. da Silva M. Beyer U. Hampel 《International Journal of Multiphase Flow》2010,36(11-12):908-915
A conductance wire mesh sensor system has been employed on a vertical 67 mm diameter pipe with the up flow of air and water mixtures. The measuring system provides time and cross-sectionally resolved information about the spatial distribution of the phases. Statistical information can be extracted and used to identify flow patterns. The fully resolved data has revealed a hitherto unreported structure has been seen in churn flow which could be linked to the wisps in wispy-annular flow. 相似文献
63.
In this paper, we present a domain decomposition method, based on the general theory of Steklov-Poincaré operators, for a class of linear exterior boundary value problems arising in potential theory and heat conductivity. We first use a Dirichlet-to-Neumann mapping, derived from boundary integral equation methods, to transform the exterior problem into an equivalent mixed boundary value problem on a bounded domain. This domain is decomposed into a finite number of annular subregions, and the Dirichlet data on the interfaces is introduced as the unknown of the associated Steklov-Poincaré problem. This problem is solved with the Richardson method by introducing a Dirichlet-Robin-type preconditioner, which yields an iteration-by-subdomains algorithm well suited for parallel computations. The corresponding analysis for the finite element approximations and some numerical experiments are also provided. 相似文献
64.
Jessica Orrego Hernandez Jaime Portilla Justo Cobo Christopher Glidewell 《Acta Crystallographica. Section C, Structural Chemistry》2015,71(5):363-368
Cyclohexylamine reacts with 5‐chloro‐3‐methyl‐1‐(pyridin‐2‐yl)‐1H‐pyrazole‐4‐carbaldehyde to give 5‐cyclohexylamino‐3‐methyl‐1‐(pyridin‐2‐yl)‐1H‐pyrazole‐4‐carbaldehyde, C16H20N4O, (I), formed by nucleophilic substitution, but with 5‐chloro‐3‐methyl‐1‐phenyl‐1H‐pyrazole‐4‐carbaldehyde the product is (Z)‐4‐[(cyclohexylamino)methylidene]‐3‐methyl‐1‐phenyl‐1H‐pyrazol‐5(4H)‐one, C17H21N3O, (II), formed by condensation followed by hydrolysis. Compound (II) crystallizes with Z′ = 2, and in one of the two independent molecular types the cyclohexylamine unit is disordered over two sets of atomic sites having occupancies of 0.65 (3) and 0.35 (3). The vinylogous amide portion in each compound shows evidence of electronic polarization, such that in each the O atom carries a partial negative charge and the N atom of the cyclohexylamine portion carries a partial positive charge. The molecules of (I) contain an intramolecular N—H...N hydrogen bond, and they are linked by C—H...O hydrogen bonds to form sheets. Each of the two independent molecules of (II) contains an intramolecular N—H...O hydrogen bond and each molecular type forms a centrosymmetric dimer containing one R22(4) ring and two inversion‐related S(6) rings. 相似文献
65.
66.
Floquet N Hernandez JF Boucher JL Martinez J 《Journal of chemical information and modeling》2011,51(6):1325-1335
Nitric oxide (NO) is an important signaling molecule produced by a family of enzymes called nitric oxide synthases (NOS). Because NO is involved in various pathological conditions, the development of potent and isoform-selective NOS inhibitors is an important challenge. In the present study, the dimer of oxygenase domain of human iNOS (iNOSoxy) complexed to its natural substrate L-arginine (L-Arg) and both heme and tetrahydro-L-biopterin (BH4) cofactors was studied through multiple molecular dynamics simulations. Starting from the X-ray structure available for that complex (PDB: 1NSI ), a 16 ns equilibration trajectory was first obtained. Twelve dynamics of slow extraction of L-Arg out from the iNOSoxy active site were then performed. The steered molecular dynamics (SMD) approach was used starting from three different points of the reference trajectory for a total simulation time of 35 ns. A probable unbinding/binding pathway of L-Arg was characterized. It was suggested that a driving force directed the substrate toward the heme pocket. Key intermediate steps/residues along the access route to the active site were identified along this "funnel shape" pathway and compared to existing data. A quasi-normal mode analysis performed on the SMD data suggested that large collective motions of the protein may be involved in L-Arg binding and that opening the route to the active site in one monomer promoted an inverse, closing motion in the second monomer. Finally, our findings might help to rationalize the design of human iNOS isoform competitive inhibitors. 相似文献
67.
This paper reports the synthesis and dopant dependent electrical and sensing properties of single poly(ethylenedioxythiophene) (PEDOT) nanowire sensors. Dopant type (i.e. polystyrenesulfonate (PSS(-)) and perchlorate (ClO(4)(-))) and solvent (i.e. acetonitrile and 1 : 1 water-acetonitrile mixture) were adjusted to change the conjugation length and hydrophilicity of nanowires which resulted in change of the electrical properties and sensing performance. Temperature dependent coefficient of resistance (TCR) indicated that the electrical properties are greatly dependent on dopants and electrolyte where greater disorder was found in PSS(-) doped PEDOT nanowires compared to ClO(4)(-) doped nanowires. Upon exposure to different analytes including water vapor and volatile organic compounds, these nanowire devices displayed substantially different sensing characteristics. ClO(4)(-) doped PEDOT nanowires from an acetonitrile bath show superior sensing responses toward less electronegative analytes and followed a power law dependence on the analyte concentration at high partial pressures. These tunable sensing properties were attributed to variation in the conjugation lengths, dopant type and concentration of the wires which may be attributed to two distinct sensing mechanisms: swelling within the bulk of the nanowire and work function modulation of Schottky barrier junction between nanowire and electrodes. 相似文献
68.
Evstigneev VP Mosunov AA Buchelnikov AS Hernandez Santiago AA Evstigneev MP 《The Journal of chemical physics》2011,134(19):194902
Equations for the mass conservation law and the molecular parameters observed in spectroscopic experiments have been derived for non-covalent, non-cooperative, one-dimensional self-assembly in systems containing two types of interacting molecules (hetero-association), taking into account "reflected" complexes and "edge effects." 相似文献
69.
Belfield KD Bondar MV Hernandez FE Przhonska OV Wang X Yao S 《Physical chemistry chemical physics : PCCP》2011,13(10):4303-4310
The linear photophysical, excited state absorption (ESA), superfluorescence, and two-photon absorption (2PA) properties of 4,4'-(1E,1'E)-2,2'-(7,7'(1E,1'E)2,2'(4,4'-sulfonylbis(4,1-phenylene))bis(ethane-2,1-diyl)bis(9,9-didecy-9H-fluorene7,2-diyl))bis(ethane-2,1-diyl)bis(N,N-diphenylaniline) (1) were investigated in organic and aqueous media with respect to its potential application in biological imaging. The analysis of linear photophysical properties revealed a rather complex nature of the main one-photon absorption band, strong solvatochromic effects in the steady-state fluorescence spectra, single-exponential fluorescence decay, and high fluorescence quantum yields in organic solvents (≈1.0). The ESA spectra of 1 suggested potential for light amplification in nonpolar media while efficient superfluorescence in cyclohexane was demonstrated. The degenerate 2PA spectra of 1 were obtained over a broad spectral range (640-900 nm), using a standard two-photon induced fluorescence method under 1 kHz femtosecond excitation. Two well defined 2PA bands with maximum 2PA cross sections up to 1700 GM in the higher energy, short wavelength band and ≈1200 GM in the lower energy, long wavelength band of 1 were shown. The potential use of 1 in bioimaging was demonstrated via one- and two-photon in vitro fluorescence imaging of HCT 116 cells. 相似文献
70.
Potential Analysis - Convergence is proved for solutions un of Dirichlet problems in regions with many small excluded sets (holes), as the holes become smaller and more numerous. The problem is... 相似文献