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91.
Sun-Ae Moon Tae-Gu Lee Jin-Huek Hur Ki-Moo Heo Hoseon Yoo Seung-Jae Moon Jae-Heon Lee 《Heat and Mass Transfer》2008,44(11):1345-1353
In this paper, the averaged reentering rates of the densely built cooling towers, which form banks on the building roof in
Seoul, Korea have been predicted by a numerical method according to various summer wind conditions and roof wall types. The
averaged reentering rates of all the cooling towers are compared according to two wall types to study the effect of the intake
outdoor air louver on the reentering rates. Consequently, two findings are drawn as follows. (1) With a curtain wall, the
averaged reentering rates of the total cooling towers against the west and the south wind at ν = 5 m/s are 13.3 and 24.4%, respectively. Therefore, it is strongly needed to find a method to reduce the reentering of the
discharged air from the cooling towers. (2) In the case of a louver wall, the averaged reentering rates of the cooling towers
with the west and south wind at ν = 5 m/s are 2.5 and 9.74%, respectively, which have been estimated to be lower than those of the curtain wall. Therefore,
the louver wall can be suitably adopted to reduce the reentering of the discharged air from the cooling towers in the present
study. 相似文献
92.
B.S. Kang S. Kim F. Ren K. Ip Y.W. Heo B.P. Gila C.R. Abernathy D.P. Norton S.J. Pearton 《Applied Physics A: Materials Science & Processing》2005,80(2):259-261
Bulk Pt/ZnO Schottky rectifiers show gas sensitivities for CO of 4% and 8%, respectively, at 150 °C for 1 and 10% CO in N2. The current or voltage changes are time dependent, with an activation energy of 40.7 kJmol-1. Over a limited range of partial pressures of CO (PCO) in the ambient gas, the on-state resistance R of the sensor at fixed bias voltage decreased according to R=(RO+A(PCO)0.5)-1, where A is a constant and RO is the resistance in N2. Since these devices are also sensitive to H2 and C2H4, the ZnO rectifiers appear promising for a range of gas-sensing applications. PACS 81.05.Dz; 73.61.Ga; 72.80.Ey 相似文献
93.
A photochromic phenoxyquinone based cyanide ion sensor 总被引:1,自引:0,他引:1
We have developed a new chemosensor system for cyanide ion that is based on a photochromic material. We observed that addition of cyanide anion to a UV irradiated solution of a phenoxynaphthacenequinone derivative brought about a significant change in the absorption spectra that enabled detection of cyanide ion in a selective and sensitive manner. A carbanion intermediate was shown to be responsible for the long wavelength absorption band (630-940 nm) that is generated by cyanide addition. 相似文献
94.
Hyun Ju Park Jong-Ki Jeon Dong Jin Suh Young-Woong Suh Hyeon Su Heo Young-Kwon Park 《Catalysis Surveys from Asia》2011,15(3):161-180
Bio-oil has attracted considerable interest as a promising renewable energy resource because it can be utilized as a feedstock
in integrated bio-refineries for the production of highly valuable chemicals and next-generation hydrocarbon fuels. However,
it is necessary to improve the bio-oil quality before it can be fed to bio-refineries. Currently, catalytic vapor cracking
seems a more attractive process than catalytic upgrading technologies, such as hydrotreating and esterification, in order
to improve the bio-oil quality. This review presents a summary of recent research and the state of art technology for the
catalytic vapor cracking of bio-oil, focusing on the catalysts applied, upgrading methods and reaction mechanisms. 相似文献
95.
Geetha Thiagarajan Effendi Widjaja Jun Hyuk Heo Jason K. Cheung Busolo Wabuyele Xiaodun Mou Mohammed Shameem 《Journal of Raman spectroscopy : JRS》2015,46(6):531-536
Structural complexity of biological drug products presents an analytical challenge in terms of early detection of aggregation and/or degradation. In the present study, Raman and Raman optical activity (ROA) were evaluated for their sensitivity to detect heat‐induced molecular instability in an Immunoglobulin G4 subclass therapeutic monoclonal antibody present in its formulation matrix. The therapeutic antibody was subjected to heat stress at 50 °C and was analyzed at various time points up to 1 month. The current results suggest that Raman and ROA are sensitive to early‐stage detection of heat‐induced instability of the antibody, in which significant changes could be observed at 1 week of stress. ROA could provide early detection of the subtle differences at the tertiary structure level in a heat‐stressed monoclonal antibody and Raman/ROA spectra could provide early detection in secondary structural changes as well. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
96.
Das A Heo J Jankowski M Guo W Zhang L Deng H Bhattacharya P 《Physical review letters》2011,107(6):066405
We report ultralow threshold polariton lasing from a single GaN nanowire strongly coupled to a large-area dielectric microcavity. The threshold carrier density is 3 orders of magnitude lower than that of photon lasing observed in the same device, and 2 orders of magnitude lower than any existing room-temperature polariton devices. Spectral, polarization, and coherence properties of the emission were measured to confirm polariton lasing. 相似文献
97.
Haejeong Heo Jong-Hwan Kim Hyun Jung Lim Jeong-Hwan Kim Miso Kim Jaemoon Koh Joo-Young Im Bo-Kyung Kim Misun Won Ji-Hwan Park Yang-Ji Shin Mi Ran Yun Byoung Chul Cho Yong Sung Kim Seon-Young Kim Mirang Kim 《Experimental & molecular medicine》2022,54(8):1236
Acquired resistance to inhibitors of anaplastic lymphoma kinase (ALK) is a major clinical challenge for ALK fusion-positive non-small-cell lung cancer (NSCLC). In the absence of secondary ALK mutations, epigenetic reprogramming is one of the main mechanisms of drug resistance, as it leads to phenotype switching that occurs during the epithelial-to-mesenchymal transition (EMT). Although drug-induced epigenetic reprogramming is believed to alter the sensitivity of cancer cells to anticancer treatments, there is still much to learn about overcoming drug resistance. In this study, we used an in vitro model of ceritinib-resistant NSCLC and employed genome-wide DNA methylation analysis in combination with single-cell (sc) RNA-seq to identify cytidine deaminase (CDA), a pyrimidine salvage pathway enzyme, as a candidate drug target. CDA was hypomethylated and upregulated in ceritinib-resistant cells. CDA-overexpressing cells were rarely but definitively detected in the naïve cell population by scRNA-seq, and their abundance was increased in the acquired-resistance population. Knockdown of CDA had antiproliferative effects on resistant cells and reversed the EMT phenotype. Treatment with epigenome-related nucleosides such as 5-formyl-2′-deoxycytidine selectively ablated CDA-overexpressing resistant cells via accumulation of DNA damage. Collectively, our data suggest that targeting CDA metabolism using epigenome-related nucleosides represents a potential new therapeutic strategy for overcoming ALK inhibitor resistance in NSCLC.Subject terms: Gene expression, Epigenomics, Non-small-cell lung cancer 相似文献
98.
99.
Manh Heun Kim Kwan Hee Park So Ra Kim Kwang Jun Park Myeong Hwan Oh Jun Hyeok Heo 《Natural product research》2016,30(2):206-213
Two new phenolic compounds, 4-O-glucopyranosyl-5-O-caffeoylshikimic acid (1) and 2,3-digalloyl oregonin (2), were isolated along with eight known phenolic compounds (3–10) from an 80% acetone extract of Alnus sibirica leaves. The chemical structures of these compounds were elucidated using 1D/2D nuclear magnetic resonance and high resolution-MS. The anti-oxidative activities of these compounds were determined by assaying their 1,1-diphenyl-2-picrylhydrazyl radical and nitroblue tetrazolium superoxide anion scavenging activity. All of the isolated phenolic compounds (1–10) exhibited potent anti-oxidative activities. In particular, 2 and 4, which are diarylheptanoids, and 10 which is ellagitannin exhibited excellent anti-oxidative activities with almost the same potency as that of the positive controls L-ascorbic acid and allopurinol. 相似文献
100.
Horacek M Min JS Heo S Park J Papesch W 《Rapid communications in mass spectrometry : RCM》2008,22(11):1763-1766
Forensic scientists are frequently requested to differentiate between, or compare, adhesive tapes from a suspect or a crime scene. The most common polymers used to back packaging tape are polypropylene and polyvinyl chloride. Much of the oriented polypropylene (OPP) needed to produce packaging tapes, regardless of the tape brand, is supplied by just a few polymer manufacturers. Consequently, the composition of the backing material varies little. Therefore, the discriminating power of classical methods (physical fit, tape dimensions, colour, morphology, FTIR, PyGC/MS, etc.) is limited. Analysis of stable isotopes using isotope ratio mass spectrometry (IRMS) has been applied in the broad area of forensics and it has been reported that isotope analysis is a valuable tool for the identification of adhesive tapes. We have tested the usefulness of this method by distinguishing different South Korean adhesive tapes produced by just a few manufacturers in the small South Korean market. Korean adhesive tapes were collected and analysed for their isotope signatures. The glue of the tapes was separated from the backing material and these sub-samples were analysed for their H- and C-isotope composition. The result shows the possibility for discriminating most tape samples, even from the same brand. Variations within single rolls have also been investigated, where no variations in H- and C-isotope composition significantly exceeding the standard deviation were found. 相似文献