Evidence for a wide extra-astrocytic distribution of S100B in human brain

Background  

S100B is considered an astrocytic in-situ marker and protein levels in cerebrospinal fluid (CSF) or serum are often used as biomarker for astrocytic damage or dysfunction. However, studies on S100B in the human brain are rare. Thus, the distribution of S100B was studied by immunohistochemistry in adult human brains to evaluate its cell-type specificity.     

The Aza‐Morita–Baylis–Hillman Reaction: A Mechanistic and Kinetic Study

The aza‐Morita‐Baylis–Hillman (aza‐MBH) reaction has been studied in a variety of solvents, a selection of imine substrates and with various combinations of PPh₃ and para‐nitrophenol as the catalyst system. The measured kinetic data indicates that the effects of solvent and protic co‐catalyst are strongly interdependent. These results are most easily reconciled with a mechanistic model involving the reversible protonation of zwitterionic intermediates in the catalytic cycle, which is also supported by ³¹P NMR spectroscopy and quantum chemical studies.     

Two remarks on generalized hexagons

In this paper, the point-distance-2-regular hexagons are characterized as the only hexagons for which the intersection sets have size one and containing on ovoidal subspace all the points of which are 3-regular. We also give a characterization of the finite split Cayley hexagon of even order.     

Strategies of loop recombination in ciliates

The concept of breakpoint graph, known from the theory of sorting by reversal, has been successfully applied in the theory of gene assembly in ciliates. We further investigate its usage for gene assembly, and show that the graph allows for an efficient characterization of the possible orders of loop recombination operations (one of the three types of molecular operations that accomplish gene assembly) for a given gene during gene assembly. The characterization is based on spanning trees within a graph built upon the connected components in the breakpoint graph. We work in the abstract and more general setting of so-called legal strings.     

Zum Nachweis von Salizyls?ureverbindungen und Antifebrin im Harn

Ohne Zusammenfassung     

An EOX method for the detection of halogenated hydrocarbons in soil samples

Analytical and Bioanalytical Chemistry -