Facile Synthesis of Novel Functionalized Pyridine Annulated Oxirane Methyl Coumarins

A one‐pot synthesis of series of new ethyl‐7‐oxirane methyl‐2‐methyl‐5‐oxo‐5H‐benzopyrano[3,4‐c]pyridine‐1‐carboxylates ( 6a–e ) from 3‐allyl‐2‐hydroxy acetophenones ( 1a–e ) via key intermediate 8‐allyl‐4‐chloro‐3‐formyl coumarins ( 2a–e ) is described. The reaction involves Michael addition of 8‐allyl‐4‐chloro‐3‐formyl coumarins with ethyl 3‐amino crotonoate followed by cyclization, and per acid epoxidation proceeds under mild conditions and gives products in good‐to‐excellent yields.