Estimation of parameters in parity-violating nuclear force using single-Z-boson factorisation relations

Using suitable factorisation relations and factorisation dependent neutralcurrent parameters of Hung and Sakurai, the neutral current contributions to the parity violating parameters in nuclear force are estimated. Using Cabbibo rotation and Fierz transformation, the charge current contribution is added. It is found that three out of four parity violating parameters can be calculated with respect to their signs and magnitudes. The range of values of the other parameter appears to be small.     

Synthesis,molecular and supramolecular structure,spectroscopy and electrochemistry of a dialkoxo-bridged diuranyl(VI) compound

The synthesis, molecular and supramolecular structure, spectroscopy and electrochemistry of a dialkoxo-bridged diuranyl(VI) compound [(UO₂)₂(L)₂(dimethylformamide)₂] (1) derived from the Schiff base ligand H₂L, obtained on condensation of 3-methoxysalicylaldehyde with 2-aminoethanol, have been described. The compound has been characterized by IR, UV–Vis, NMR and mass spectra, as well as by single crystal X-ray structure determination. The title compound crystallizes in the monoclinic P2₁/n space group with the following unit cell parameters a = 10.5713(2) Å, b = 11.9895(2) Å, c = 12.9372(2) Å, β = 102.773(3)° and Z = 2. The structure of 1 reveals that it is a dialkoxo-bridged dinuclear compound of uranium(VI) containing two deprotonated ligands, [L]²⁻, two dimethylformamide (dmf) molecules and two UO₂²⁺ centers. The coordination geometry around the uranium(VI) center is distorted pentagonal bipyramidal; two uranyl oxygens occupy the axial positions, while the basal pentagonal plane is defined by a phenoxo oxygen, two bridging alkoxo oxygens, one imine nitrogen, and one dmf oxygen. Three C–H?O type hydrogen bonds involving one uranyl oxygen, two dmf hydrogens and the imine hydrogen link the dinuclear units into a two-dimensional network. The ESI-MS spectrum of 1 in dimethylsulfoxide exhibits two peaks at m/z = 464.17 and 927.26, which are assignable to [(UO₂)₂L₂H]⁺ (60%) and [(UO₂)₂LH]⁺ (100%) cations, respectively. Cyclic voltammetric measurements of 1 reveal that the uranium(VI) center is reduced quasireversibly at E_1/2 = −1112 mV with ΔE_P = 97 mV.     

Synthesis and biological evaluation of bile acid dimers linked with 1,2,3-triazole and bis-beta-lactam

We report herein the synthesis and biological evaluation of bile acid dimers linked through 1,2,3-triazole and bis-beta-lactam. The dimers were synthesized using 1,3-dipolar cycloaddition reaction of diazido bis-beta-lactams , and terminal alkynes derived from cholic acid/deoxycholic acid in the presence of Cu(i) catalyst (click chemistry). These novel molecules were evaluated in vitro for their antifungal and antibacterial activity. Most of the compounds exhibited significant antifungal as well as antibacterial activity against all the tested fungal and bacterial strains. Moreover, their in vitro cytotoxicities towards HEK-293 and MCF-7 cells were also established.     

Sourcing under incomplete information and negative capacity-cost correlation

We study a sourcing problem where a buyer reserves capacity from a set of suppliers. The suppliers have finite capacity and their unit production cost is a decreasing function of their capacity, implying scale economies. The capacity of each supplier and therefore the cost is his private information. The buyer and other suppliers only know the probability distribution of the supplier’s capacity. The buyer’s demand is random and she has to decide how much capacity to reserve in advance from a subset of suppliers and how much to source from marketplace. In this study we determine the buyer’s optimum reservation quantity and the size of the supply base. We find the presence of such capacity cost correlation leads to supply base reduction.     

Spectroscopy and Dynamics of Cryptolepine in the Nanocavity of Cucurbit[7]uril and DNA

Herein, we explored the photophysical properties of the antimalarial, anticancer drug cryptolepine (CRYP) in the presence of the macrocyclic host cucurbit[7]uril (CB7) and DNA with the help of steady‐state and time‐resolved fluorescence techniques. Ground‐state and excited‐state calculations based on density functional theory were also performed to obtain insight into the shape, electron density distribution, and energetics of the molecular orbitals of CRYP. CRYP exists in two forms depending on the pH of the medium, namely, a cationic (charge transfer) form and a neutral form, which emit at λ=540 and 420 nm, respectively. In a buffer solution of pH 7, the drug exists in the cationic form, and upon encapsulation with CB7, it exhibits a huge enhancement in fluorescence intensity due to a decrement in nonradiative decay pathways of the emitting cryptolepine species. Furthermore, docking and quantum chemical calculations were employed to decipher the molecular orientation of the drug in the inclusion complex. Studies with natural DNA indicate that CRYP molecules intercalate into DNA, which leads to a huge quenching of the fluorescence of CRYP. Keeping this in mind, we studied the DNA‐assisted release of CRYP molecules from the nanocavity of CB7. Strikingly, DNA alone could not remove the drug from the nanocavity of CB7. However, an external stimulus such as acetylcholine chloride was able to displace CRYP from the nanocavity, and subsequently, the displaced drug could bind to DNA.     

Chemistry of enediynyl azides: activation through a novel pathway

The spontaneous activation of a nonaromatic enediynyl azide under ambient conditions has been demonstrated. The aromatic enediyne followed the expected cycloaddition with the alkene in the neighbouring arm to form a stable bridged bicyclic enediyne.     

A novel biflavonyloxymethane from Pongamia pinnata and its radical quenching activity

The root bark of Pongamia pinnata Pierre (syn P. glabra Vent.) has afforded a new biflavonyloxymethane, pongabiflavone, along with a known furanoflavone, 3-methoxy-(7, 8, 2", 3") furanoflavone. The structure of this new compound was elucidated from extensive spectral studies, including 2D-NMR spectroscopic experiments. The antioxidant, radical quenching activity- superoxide and nitric oxide quenching activities of both pongabiflavone and previously isolated karanjabiflavone have been evaluated which can be a key to cure Psoriasis.     

First examples of two ferromagnetic end-to-end cyanate bridged 1D linear coordination polymers of nickel(ii) containing an unsymmetrical diamine

Two new end-to-end (EE) cyanate bridged 1D coordination polymers of Ni(II) are isolated which contain linear (180°) Ni-N-C and Ni-O-C angles in Ni-NCO-Ni bridges and show ferromagnetic (F) coupling in agreement with the reported theoretical model for linear EE bridges.     

Rabi type oscillations in damped two-dimensional single electron quantum dots

We present a quantized model of a harmonically confined dot atom with inherent damping in the presence of a transverse magnetic field. The model leads to a non-Hermitian Hamiltonian in coordinate space. We have analytically studied the effects of damping on Rabi type oscillations of the system. The model explains the decoherence of Rabi oscillations in a Josephson Junction.     

Role of metal ions in growth and stability of Langmuir-Blodgett films on homogeneous and heterogeneous surfaces

Structure and stability of cadmium arachidate (CdA) Langmuir-Blodgett (LB) films on homogeneous (i.e., OH-, H-passivated Si(001) substrates) and heterogeneous (i.e., Br-passivated Si(001) substrates) surfaces were studied using X-ray reflectivity and atomic force microscopy techniques and compared with those of nickel arachidate (NiA) LB films. While on OH-passivated Si, an asymmetric monolayer (AML) structure starts to grow, on H-passivated Si, a symmetric monolayer (SML) of CdA forms, although for both the films, pinhole-type defects are present as usual. However, on heterogeneous Br-passivated Si substrates, a combination of AML, SML, shifted SML and SML on top of AML (i.e., AML/SML), all types of structures are found to grow in such a way that, due to the variation of heights in the out-of-plane direction, ring-shaped in-plane nanopatterns of CdA molecules are generated. Probably due to stronger head-head interactions and higher metal ion-carboxylic ligand bond strength for CdA molecules compared to NiA, easy flipping of SML on top of another preformed SML, i.e. a SML/SML structure formation was not possible and as a result a wave-like modulation is observed for the CdA film on such heterogeneous substrate. The presence of hydrophilic/hydrophobic interfacial stress on the heterogeneous substrate thus modifies the deposited molecular structure so that the top surface morphology for a CdA film is similar to monolayer buckling while that for NiA film is similar to monolayer collapse.