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131.
Muhammad Taha Sadia Sultan Muhammad Herizal M. Qaiser Fatmi Manikandan Selvaraj Kalavathy Ramasamy Sobia Ahsan Halim Siong Meng Lim Fazal Rahim Kamran Ashraf Adeeb Shehzad 《Journal of Saudi Chemical Society》2019,23(8):1168-1179
To find out effective anticancer compounds we synthesized (1–30) derivatives of 4-isopropylbenzoylhydrazone and evaluated for anticancer potential. The compounds 3, 9, 12, 23, 26 and 28 showed better activities ranging (0.39–1.1 µg/ml) than the standard (1.53 ± 0.01 µg/ml). In line with this, compounds 2, 6, 24, 25 and 29 exhibited better activities compared to the second standard (5FU 4.60 ± 0.01 µg/ml). The best molecular docked complex between the BRCA1 structure and the 1–30 derivatives were analyzed based on the Glide docked score and binding orientation for both the SP and XP mode. The 2D-QSAR analysis reflected a significant correlation between the experimental and the predicted biological activities. The above-mentioned compounds were also assessed by various spectroscopic techniques. 相似文献
132.
Abazov VM Abbott B Abolins M Acharya BS Adams M Adams T Aguilo E Ahn SH Ahsan M Alexeev GD Alkhazov G Alton A Alverson G Alves GA Anastasoaie M Ancu LS Andeen T Anderson S Andrieu B Anzelc MS Arnoud Y Arov M Arthaud M Askew A Asman B Assis Jesus AC Atramentov O Autermann C Avila C Ay C Badaud F Baden A Bagby L Baldin B Bandurin DV Banerjee P Banerjee S Barberis E Barfuss AF Bargassa P Baringer P Barreto J Bartlett JF Bassler U Bauer D Beale S Bean A Begalli M Begel M Belanger-Champagne C 《Physical review letters》2008,101(6):062001
We report on a measurement of the inclusive jet cross section in pp[over ] collisions at a center-of-mass energy sqrt[s]=1.96 TeV using data collected by the D0 experiment at the Fermilab Tevatron Collider corresponding to an integrated luminosity of 0.70 fb;{-1}. The data cover jet transverse momenta from 50 to 600 GeV and jet rapidities in the range -2.4 to 2.4. Detailed studies of correlations between systematic uncertainties in transverse momentum and rapidity are presented, and the cross section measurements are found to be in good agreement with next-to-leading order QCD calculations. 相似文献
133.
Abazov VM Abbott B Abolins M Acharya BS Adams M Adams T Aguilo E Ahn SH Ahsan M Alexeev GD Alkhazov G Alton A Alverson G Alves GA Anastasoaie M Ancu LS Andeen T Anderson S Andrieu B Anzelc MS Arnoud Y Arov M Arthaud M Askew A Asman B Assis Jesus AC Atramentov O Autermann C Avila C Ay C Badaud F Baden A Bagby L Baldin B Bandurin DV Banerjee S Banerjee P Barberis E Barfuss AF Bargassa P Baringer P Barreto J Bartlett JF Bassler U Bauer D Beale S Bean A Begalli M Begel M Belanger-Champagne C 《Physical review letters》2008,100(10):101801
We study the flavor-changing-neutral-current process c-->u micro(+) micro(-) using 1.3 fb(-1) of pp[over ] collisions at square root s = 1.96 TeV recorded by the D0 detector operating at the Fermilab Tevatron Collider. We see clear indications of the charged-current mediated D(s)(+) and D(+)-->phipi(+) --> micro(+)micro(-)pi(+) final states with significance greater than 4 standard deviations above background for the D(+) state. We search for the continuum neutral-current decay of D(+)-->pi(+) micro(+) micro(-) in the dimuon invariant mass spectrum away from the phi resonance. We see no evidence of signal above background and set a limit of B(D(+) --> pi(+) micro(+) micro(-))<3.9 x 10(-6) at the 90% C.L. This limit places the most stringent constraint on new phenomena in the c--> u micro(+) micro(-) transition. 相似文献
134.
Abazov VM Abbott B Abolins M Acharya BS Adams M Adams T Aguilo E Ahn SH Ahsan M Alexeev GD Alkhazov G Alton A Alverson G Alves GA Anastasoaie M Ancu LS Andeen T Anderson S Andrieu B Anzelc MS Arnoud Y Arov M Arthaud M Askew A Asman B Jesus AC Atramentov O Autermann C Avila C Ay C Badaud F Baden A Bagby L Baldin B Bandurin DV Banerjee S Banerjee P Barberis E Barfuss AF Bargassa P Baringer P Barreto J Bartlett JF Bassler U Bauer D Beale S Bean A Begalli M Begel M Belanger-Champagne C Bellantoni L 《Physical review letters》2008,100(10):102002
We present a measurement of the shape of the Z/gamma* boson transverse momentum (q(T)) distribution in pp --> Z/gamma* --> e(+)e(-) + X events at a center-of-mass energy of 1.96 TeV using 0.98 fb(-1) of data collected with the D0 detector at the Fermilab Tevatron collider. The data are found to be consistent with the resummation prediction at low q(T), but above the perturbative QCD calculation in the region of q(T)>30 GeV/c. Using events with q(T)<30 GeV/c, we extract the value of g(2), one of the nonperturbative parameters for the resummation calculation. Data at large boson rapidity y are compared with the prediction of resummation and with alternative models that employ a resummed form factor with modifications in the small Bjorken x region of the proton wave function. 相似文献
135.
B.S. Yilbas C. Karatas I. Uslan O. Keles Y. Usta Z. Yilbas M. Ahsan 《Optics and Lasers in Engineering》2008,46(10):777-784
In some applications, laser cutting of wedge surfaces cannot be avoided in sheet metal processing and the quality of the end product defines the applicability of the laser-cutting process in such situations. In the present study, CO2 laser cutting of the wedge surfaces as well as normal surfaces (normal to laser beam axis) is considered and the end product quality is assessed using the international standards for thermal cutting. The cut surfaces are examined by the optical microscopy and geometric features of the cut edges such as out of flatness and dross height are measured from the micrographs. A neural network is introduced to classify the striation patterns of the cut surfaces. It is found that the dross height and out of flatness are influenced significantly by the laser output power, particularly for wedge-cutting situation. Moreover, the cut quality improves at certain value of the laser power intensity. 相似文献
136.
Ali M. Haseeb Mustafa Keskin Ian L. Pegg Paul H. E. Meijer 《Fluid Phase Equilibria》1996,120(1-2):93-105
We describe a method to determine tielines for a mixture with a given volume Vt and a given mole fraction xt at fixed temperature, which is based on the orientation of the tangent plane to the Helmholtz free energy surface. The method works equally well for gas-liquid separation as for liquid-liquid separation. The method is based on a rotation in coordinate space followed by a rotation in function space which establishes the correct direction and the end points of the tieline. The mathematics is described and the general outline of a computer program to implement the method is given. This is followed by an application to a special form of the van der Waals equation, which describes the influence of chain-molecules as proposed by Tompa. The example given shows a three phase separation and the influence of the chain-length thereupon. 相似文献
137.
Completely quasi-projective monoids 总被引:3,自引:0,他引:3
138.
Kia Dashtipour Mandar Gogate Ahsan Adeel Hadi Larijani Amir Hussain 《Entropy (Basel, Switzerland)》2021,23(5)
Sentiment analysis aims to automatically classify the subject’s sentiment (e.g., positive, negative, or neutral) towards a particular aspect such as a topic, product, movie, news, etc. Deep learning has recently emerged as a powerful machine learning technique to tackle the growing demand for accurate sentiment analysis. However, the majority of research efforts are devoted to English-language only, while information of great importance is also available in other languages. This paper presents a novel, context-aware, deep-learning-driven, Persian sentiment analysis approach. Specifically, the proposed deep-learning-driven automated feature-engineering approach classifies Persian movie reviews as having positive or negative sentiments. Two deep learning algorithms, convolutional neural networks (CNN) and long-short-term memory (LSTM), are applied and compared with our previously proposed manual-feature-engineering-driven, SVM-based approach. Simulation results demonstrate that LSTM obtained a better performance as compared to multilayer perceptron (MLP), autoencoder, support vector machine (SVM), logistic regression and CNN algorithms. 相似文献
139.
Solution of fractional-order integro-differential equations using optimal homotopy asymptotic method
Nawaz Rashid Khattak Abraiz Akbar Muhammad Ahsan Sumbal Shah Zahir Khan Adam 《Journal of Thermal Analysis and Calorimetry》2021,146(3):1421-1433
Journal of Thermal Analysis and Calorimetry - In this article, a semi-analytical technique called optimal homotopy asymptotic method (OHAM) is presented for numerical solutions of fractional-order... 相似文献
140.
Wasim Ul Bari Najeeb Ur Rehman Ajmal Khan Sobia Ahsan Halim Ye Yuan Mark A.T. Blaskovich Zyta M. Ziora Muhammad Zahoor Sumaira Naz Riaz Ullah Amal Alotaibi Ahmed Al-Harrasi 《Molecules (Basel, Switzerland)》2021,26(7)
In the study, two novel compounds along with two new compounds were isolated from Grewia optiva. The novel compounds have never been reported in any plant source, whereas the new compounds are reported for the first time from the studied plant. The four compounds were characterized as: 5,5,7,7,11,13-hexamethyl-2-(5-methylhexyl)icosahydro-1H-cyclopenta[a]chrysen-9-ol (IX), docosanoic acid (X), methanetriol mano formate (XI) and 2,2’-(1,4-phenylene)bis(3-methylbutanoic acid (XII). The anticholinesterase, antidiabetic, and antioxidant potentials of these compounds were determined using standard protocols. All the isolated compounds exhibited a moderate-to-good degree of activity against acetylcholinesterases (AChE) and butyrylcholinesterase (BChE). However, compound XII was particularly effective with IC50 of 55 μg/mL (against AChE) and 60 μg/mL (against BChE), and this inhibitory activity is supported by in silico docking studies. The same compound was also effective against DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid) radicals with IC50 values of 60 and 62 μg/mL, respectively. The compound also significantly inhibited the activities of α-amylase and α-glucosidase in vitro. The IC50 values for inhibition of the two enzymes were recorded as 90 and 92 μg/mL, respectively. The in vitro potentials of compound XII to treat Alzheimer’s disease (in terms of AchE and BChE inhibition), diabetes (in terms of α-amylase and α-glucosidase inhibition), and oxidative stress (in terms of free radical scavenging) suggest further in vivo investigations of the compound for assessing its efficacy, safety profile, and other parameters to proclaim the compound as a potential drug candidate. 相似文献