排序方式: 共有160条查询结果,搜索用时 15 毫秒
81.
Ahmadreza Esmaeilbeig Hamidreza Samouei Zahra Amirghofran 《Journal of organometallic chemistry》2011,696(20):3135-3142
A general approach has been designed to synthesize some mononuclear and binuclear cyclometalated platinum(II) complexes, containing aromatic N-donor ligands with the presence of one Cl−trans to carbon. In this way, cyclometalated platinum(II) complex [Pt(C^N)Cl(dmso)], 1, C^N = N(1),C(2′)-chelated, deprotonated 2-phenylpyridine and dmso = dimethylsulfoxide, was used as a precursor to react with imidazole derivatives (1-methylimidazole, 2a, imidazole, 2b,), monodentate pyridine derivatives (4-methylpyridine, 2c, pyridine, 2d,) and bidentate pyridine derivative (4,4′-bipyridine, 3 and 4,). Synthesized complexes were fully characterized by using multinuclear NMR spectroscopy (1H, 13C{1H} and 195Pt), correlation NMR spectroscopy (1H-1H COSY, 13C{1H}-1H Heteronuclear Multiple Quantum Correlation, HMQC, Heteronuclear Multiple Bond Correlation, HMBC, 15N-1H HETCOR), elemental analysis, X-ray crystallography and ESI-Mass spectrometry. Antitumor effects of mononuclear cyclometalated platinum(II) complexes 2a, 2c, 2d and 3 were determined on Jurkat, K562, and Raji cell lines and results showed reasonable cytotoxicities. 相似文献
82.
Keshavarz Farzin Mirabdolah Lavasani Arash Bayat Hamidreza 《Journal of Thermal Analysis and Calorimetry》2019,135(2):1211-1228
Journal of Thermal Analysis and Calorimetry - In the present study, the effect of nanofluid and distribution density of fin on thermal–hydraulic performance of a heat sink with drop-shaped... 相似文献
83.
In this paper, we study commutative local rings whose residue field is a high syzygy. We are able to characterize such rings with embedding dimension at most 3 as those that are Artinian and Gorenstein. 相似文献
84.
Gantumur Battogtokh Oyuntuya Gotov Nithya Subrahmanyam Young Tag Ko Hamidreza Ghandehari 《Macromolecular bioscience》2019,19(7)
Photodynamic therapy (PDT) is a promising cancer treatment approach. However, the photosensitizers (PS) used for PDT are often limited by their poor solubility and selectivity for tumors. The goal of this study is to improve water solubility and delivery of the photosensitizer 2‐[1‐hexyloxyethyl]‐2‐divinyl pyropheophorbide‐a (HPPH) to breast cancer cells. An N‐(2‐hydroxypropyl)methacrylamide (HPMA) copolymer–HPPH photosensitizer conjugate is synthesized with heat shock receptor glucose‐regulated protein 78 (GRP78), targeting to GRP78 receptors of MCF‐7 cells, which are upregulated under mild hyperthermia. It is found that the uptake of the GRP78 targeted pep‐HPMA‐HPPH copolymer conjugate in MCF‐7 cells is improved through heat induction. Under mild hyperthermia the targeted copolymers are more effective compared to free HPPH. These results show potential for the utility of mild hyperthermia and copolymer delivery vehicles to enhance the efficacy of photodynamic therapy. 相似文献
85.
Ghalamkari Safoura Khosravian Farinaz Mianesaz Hamidreza Kazemi Mohammad Behjati Mohaddeseh Hakimian Sayyed Mohammadreza Salehi Mansoor 《Applied biochemistry and biotechnology》2019,187(3):975-983
Applied Biochemistry and Biotechnology - One of the most common somatic mutations in breast cancer is found in PIK3CA with a prevalence rate of 18–45%. Different variants of this gene are... 相似文献
86.
Hamidreza Mahmoodi Kordkheili Mahmood Hosseini 《Waves in Random and Complex Media》2018,28(4):760-783
By virtue of a new scalar potential function and Hankel integral transforms, the wave propagation analysis of a thermoelastic transversely isotropic half-space is presented under buried loading and heat flux. The governing equations of the problem are the differential equations of motion and the energy equation of the coupled thermoelasticity theory. Using a scalar potential function, these coupled equations have been uncoupled and a six-order partial differential equation governing the potential function is received. The displacements, temperature, and stress components are obtained in terms of this potential function in cylindrical coordinate system. Applying the Hankel integral transform to suppress the radial variable, the governing equation for potential function is reduced to a six-order ordinary differential equation with respect to z. Solving that equation, the potential function and therefore displacements, temperature, and stresses are derived in the Hankel transformed domain for two regions. Using inversion of Hankel transform, these functions can be obtained in the real domain. The integrals of inversion Hankel transform are calculated numerically via Mathematica software. Our numerical results for displacement and temperature are calculated for surface excitations and compared with the results reported in the literature and a very good agreement is achieved. 相似文献
87.
Diabetes is a major public health problem. Development of new therapies that are able to improve glycemia management, cure diabetes, and can even protect from it, are of great interest. This study investigated the protective effect of sodium tungstate against STZ-induced beta-cell damages by means of stereological methods. Sixty rats were divided into six groups: control (C), tungstate-treated control (TC), STZ-induced diabetic (D), STZ-induced diabetic rats were treated by sodium tungstate from 1 week before STZ injection (TDB), food-restricted diabetic (FRD), and diabetic rats treated with sodium tungstate 1 week after STZ administration (TDA). Stereological estimation of pancreas volume, islets volume density, volume-weighted mean islets volume and mass of beta cells, islets, and pancreas and total number of islets were done. Islets volume density, volume-weighted mean islets volume, and mass of beta cells, islets, and pancreas of TDB group was significantly higher than D, FRD and TDA groups (P < 0.001) and was comparable to controls (C and TC groups). Total number of islets, pancreas wet weight and volume did not show any significant changes between these groups (P > 0.05).Results suggested that sodium tungstate preserves pancreatic beta cells from STZ-induced damages and diabetes induction in rats. 相似文献
88.
Hamidreza Alemohammad Ehsan Toyserkani Christ P. Paul 《Optics and Lasers in Engineering》2007,45(10):1010-1017
To realize the concept of smart tools, embedding of fiber optic sensors in the metallic structure of a cutting tool with combined laser solid freeform fabrication (LSFF) and moulding is presented in this paper. Metallic parts with embedded optical fiber sensors are capable of monitoring physical parameters like force and temperature. These sensors are advantageous relative to other conventional electric and electromagnetic sensors due to their light weight, immunity to external electromagnetic fields, small size, long-term durability, and long-range linearity. In the present work, the optical fibers (e.g., fiber Bragg grating sensor, single-mode fiber optics) are moulded under tensile forces within a mild steel casing filled by Sn–Pb to fabricate a protective layer around them. Afterwards, LSFF is utilized to deposit tungsten carbide reinforced in cobalt (WC–Co) on the surface of the mild steel component. The performance results, in which the sensor exposed to a light bandwidth, show that the maximum light power loss after embedding is about 21% implying that the fiber is not damaged during the embedding process. Also, the sensor output has a linear characteristic under compression loadings indicating that the debonding of the fiber from the protective layer is not probable. The produced samples are examined by scanning electron microscopy and X-ray diffraction to assess the physical properties of the tool. Microstructural images reveal no cracks and porosity around the fiber indicating a good bonding between the fiber and the surrounding media. Material characterizations of the manufactured tool are also discussed. 相似文献
89.
Asadi Sara Zebarjad Maedeh Masoudi Hamidreza Mehrabi Hossein 《Research on Chemical Intermediates》2022,48(1):251-265
Research on Chemical Intermediates - The aim of present investigation is survey reactivity of 2-aminopyridine and Meldrum’s acid in the presence of aryl glyoxals or aryl aldehydes. The ethyl... 相似文献
90.
Fedor M. Miloserdov David McKay Bianca K. Muoz Hamidreza Samouei Stuart A. Macgregor Vladimir V. Grushin 《Angewandte Chemie (Weinheim an der Bergstrasse, Germany)》2015,127(29):8586-8590
[(Ph3P)3Ru(L)(H)2] (where L=H2 ( 1 ) in the presence of styrene, Ph3P ( 3 ), and N2 ( 4 )) cleave the Ph X bond (X=Cl, Br, I) at RT to give [(Ph3P)3RuH(X)] ( 2 ) and PhH. A combined experimental and DFT study points to [(Ph3P)3Ru(H)2] as the reactive species generated upon spontaneous loss of L from 3 and 4 . The reaction of 3 with excess PhI displays striking kinetics which initially appears zeroth order in Ru. However mechanistic studies reveal that this is due to autocatalysis comprising two factors: 1) complex 2 , originating from the initial PhI activation with 3 , is roughly as reactive toward PhI as 3 itself; and 2) the Ph I bond cleavage with the just‐produced 2 gives rise to [(Ph3P)2RuI2], which quickly comproportionates with the still‐present 3 to recover 2 . Both the initial and onward activation reactions involve PPh3 dissociation, PhI coordination to Ru through I, rearrangement to a η2‐PhI intermediate, and Ph I oxidative addition. 相似文献