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121.
Hamid Reza Safaei Mohsen Shekouhy Athar Shirinfeshan Sudabeh Rahmanpur 《Molecular diversity》2012,16(4):669-683
CaCl2 is applied as an efficient reusable and eco-friendly bifunctional catalyst for the one-pot three-component synthesis of 4H-pyrans under ultrasonic irradiation. A broad range of substrates including the aromatic and heteroaromatic aldehydes, indoline-2,3-dione (isatin) derivatives, acenaphthylene-1,2-dione (acenaphthenequinone) and 2, 2-dihydroxy-2H-indene-1,3-dione (ninhydrin) were condensed with carbonyl compounds possessing a reactive ??-methylene group and alkylmalonates. All reactions are completed in short times, and the products are obtained in good to excellent yields. The catalyst could be recycled and reused several times without any loss of efficiency. 相似文献
122.
Tofighi-Niaki Ebrahim Asgharifard-Sharabiani Pouya Ahmadian Hamid 《Nonlinear dynamics》2018,94(4):2937-2956
Nonlinear Dynamics - Rub–impact phenomenon occurring in hydrodynamic journal bearings is one of the main malfunctions in rotating machines and causes undesirable dynamic behavior. In order to... 相似文献
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A new, mild, and novel method is described for the efficient deoxygenation of sulfoxides to their corresponding sulfides with 1,3-dithiane at room temperature in the presence of catalytic amounts of N-bromosuccinimide (NBS), 2,4,4,6-tetrabromo-2,5-cyclohexadienone (TABCO), or Br(2) as the source of electrophilic bromine. 相似文献
129.
Simultaneous microwave and ultrasound irradiation is shown as a new technique for digestion of solid and liquid samples suitable for chemical and food analysis. Its application in analytical chemistry has been shown by decreases in digestion time: determination of copper in edible oils and total Kjeldahl nitrogen. 相似文献
130.
Mohamadzadeh M Mohamadzadeh H Brammer M Sestak K Luftig RB 《Journal of immune based therapies and vaccines》2004,2(1):8
Dendritic cells (DC) are known to present exogenous protein Ag effectively to T cells. In this study we sought to identify
the proteases that DC employ during antigen processing. The murine epidermal-derived DC line Xs52, when pulsed with PPD, optimally
activated the PPD-reactive Th1 clone LNC.2F1 as well as the Th2 clone LNC.4k1, and this activation was completely blocked
by chloroquine pretreatment. These results validate the capacity of XS52 DC to digest PPD into immunogenic peptides inducing
antigen specific T cell immune responses. XS52 DC, as well as splenic DC and DCs derived from bone marrow degraded standard
substrates for cathepsins B, C, D/E, H, J, and L, tryptase, and chymases, indicating that DC express a variety of protease
activities. Treatment of XS52 DC with pepstatin A, an inhibitor of aspartic acid proteases, completely abrogated their capacity
to present native PPD, but not trypsin-digested PPD fragments to Th1 and Th2 cell clones. Pepstatin A also inhibited cathepsin
D/E activity selectively among the XS52 DC-associated protease activities. On the other hand, inhibitors of serine proteases
(dichloroisocoumarin, DCI) or of cystein proteases (E-64) did not impair XS52 DC presentation of PPD, nor did they inhibit
cathepsin D/E activity. Finally, all tested DC populations (XS52 DC, splenic DC, and bone marrow-derived DC) constitutively
expressed cathepsin D mRNA. These results suggest that DC primarily employ cathepsin D (and perhaps E) to digest PPD into
antigenic peptides. 相似文献