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941.
Various feruloylated arabinose- and galactose-containing mono- and disaccharides with known linkage configurations (2-O-(trans-feruloyl)-L-arabinopyranose, 5-O-(trans-feruloyl)-L-arabinofuranose, O-[2-O-(trans-feruloyl)-alpha-L-arabinofuranosyl]-(1-->5)-L-arabinofuranose, and O-[6-O-(trans-feruloyl)-beta-D-galactopyranosyl]-(1-->4)-D-galactopyranose) were analyzed by electrospray ionization mass spectrometry using an ion trap or a quadrupole time-of-flight (Q-TOF) mass analyzer. Collision-induced dissociation (CID) experiments using the two mass analyzers generated similar tandem mass spectrometric (MS/MS) fragmentation patterns. However, the ester-bond cleavage ions were more abundant using the Q-TOF mass analyzer. Compared with the positive ion mode, the negative ion mode produces simpler and more useful CID product-ion patterns. For arabinose-containing feruloylated compounds, results obtained with both analyzers show that it is possible to assign the location of the feruloyl group to the O-2 or O-5 of arabinosyl residues. In the characterization of the 2-O-feruloyl and 5-O-feruloyl linkages, the relative abundance of the cross-ring fragment ions at m/z 265 (-60 u or -62 u after 18O-labelling) and at m/z 217 (-108 u or -110 u after 18O-labelling) play a relevant role. For galactose-containing feruloylated compounds, losses of 60, 90 and 120 Da observed in MS3 experiment correspond to the production of 0,2A1, 0,3A1 and (0,2A1-60 Da) cross-ring cleavage ions, respectively, fixing the location of feruloyl group at the O-6 of the galactose residue. 相似文献
942.
线粒体体外代谢热动力学研究 总被引:3,自引:1,他引:3
线粒体是细胞重要的细胞器之一,有细胞的“能源工厂”之称.因为线粒体内有许多酶,是特殊的酶催化氧化反应的场所山;所有动、植物细胞的线粒体都能通过各种营养物的氧化而产生“富能”物质ATP.采用一定的技术可将线粒体从细胞中分离出来,分离出来的线粒体中的酶系统还有一定的活性,而且线粒体内也有一定的营养物质,这样酶系统就能利用这些营养物进行代谢,从而释放出一定的能量.我们用微量热法对两种鱼肝脏线粒体进行了测量,发现线粒体代谢过程分四个阶段:停滞期、活性恢复期、稳定期、活性衰减期.在活性恢复期和活性衰减期,… 相似文献
943.
Shao-Qing Shi Ya-Guang Chen Jian Gong Zhi-Ming Dai Lun-Yu Qu 《Transition Metal Chemistry》2005,30(2):136-140
Peroxo-tantalum and tantalum mono-substituted tungstosilicates with the Keggin structure, K5[-SiW11Ta(O2) O39]18H2O (1) and K5[-SiW11TaO40]14H2O (2) respectively, and peroxo-tantalum and tantalum mono-substituted tungstophosphates with the Wells–Dawson structure K7[2-P2W17Ta(O2)O61]16H2O (3) and K7[2-P2W17TaO62]14H2O (4), respectively, were prepared by stereoselective synthesis and characterized by elemental analysis, i.r. and u.v. spectroscopy, XPS, 31P and 183W n.m.r. spectroscopy, and polarography, as well as cyclic voltammetry. The presence of a peroxo group in the complexes (1) and (3) was supported by observation of an i.r. band due to the —O—O— bond at 881 cm–1, the charge transfer bands of (2—O2)Ta at ca. 316 and 389 nm, the O1s binding energy at 532.0 eV and a new irreversible reduction polarographic wave at E1/2 0.1 V, assigned to the reduction of peroxo group and which enhances the oxidant properties of the heteropoly anions. There are six lines for complex (1) and nine lines for complex (3) in the 183W n.m.r. spectra, showing that the complex (1) has a mono-substituted Keggin structure and complex (3) has a mono-substituted 2-Wells–Dawson structure. The catalytic activities of the complexes with respect to epoxidation of maleic acid with H2O2 as oxidant were examined and the best result, 83.5% yield, was obtained for [(C4H9)4N]5[-SiW11Ta(O)2O39]·18H2O. 相似文献
944.
同步荧光—双波长法同时测定抗坏血酸和丙酮酸 总被引:16,自引:0,他引:16
提出一种同时测定抗坏血酸和丙酮酸的同步荧光分析法。选择激发单色器和发射单色器的波长差△λ=80nm进行同步扫描,两者的特征峰发明明显“错位”而部分分离。本法用于水果中抗坏血酸和丙酮酸的同时测定,结果满意。 相似文献
945.
The article describes a method for the determination of (187)Os in molybdenite by isotope dilution inductively coupled plasma-mass spectrometry (ID-ICP-MS) with neutron-induced (186)Os and (188)Os spike. The spike used in the present work was prepared in line with the principle by which artificial nuclides are produced in a nuclear reaction. The concentration and isotopic composition of osmium in the prepared spike were evaluated accurately with the isotope dilution method, using negative thermal ion mass spectrometry (N-TIMS). The advantage of this method is that using (186)Os and (188)Os double spikes can effectively compensate for the mass discrimination effects of ICP-MS. Thus, the common correction practice for mass bias in the isotope dilution method with a single spike is unnecessary. In addition, the method enables one to reduce the determined error arising from instrumental instability. The precision for the (187)Os/((186)Os+(188)Os) ratio was approximately 2% (2sigma, RSD), but in the case of (187)Os/(186)Os, (187)Os/(188)Os and (186)Os/(188)Os, precision ranged from 2.0 to 8% (2sigma, RSD). The results for (187)Os concentration in a molybdenite sample determined with this method showed good agreement with reference values. 相似文献
946.
An end-channel amperometric detector with a guide tube for working electrode was designed and integrated on a home-made glass microchip. The guide tube was directly patterned and fabricated at the end of the detection reservoir, which made the fixation and alignment of working electrode relatively easy. The fabrication was carried out in a two-step etching process. A 30 μm carbon fiber microdisk electrode and Pt cathode were also integrated onto the amperometric detector. The characteristics and primary performance of the home-made microchip capillary electrophoresis (MCCE) were investigated with neurotransmitters. The baseline separation of dopamine (DA), catechol (CA) and epinephrine (EP) was achieved within 80 s. Separation parameters such as injection time, buffer components, pH of the buffer were studied. Relative standard deviations of not more than 6.0% were obtained for both peak currents and migration times. Under the selected separation conditions, the response for DA was linear from 5 to 200 μM and from 20 to 800 μM for CA. The limits of detection of DA and CA were 0.51 and 2.9 μM, respectively (S/N=3). 相似文献
947.
The acid-base properties of the antihistamine (H1 receptor antagonist) cetirizine have been studied by using a previously developed multiwavelength spectrophotometric titration method. A new computational procedure called "Two-Step-Divide-and-Conquer" (TSDC), which applied evolving factor analysis (EFA) and target factor analysis (TFA), has been derived to unravel the micro-equilibria of the triprotic zwitterionic compound from the spectral data. We have demonstrated that a single spectrophotometric titration experiment is sufficient to determine the 12 unknown microconstants and the distribution of microspecies, which are in good agreement with literature values, where available. 相似文献
948.
The immobilization of surface-derivatized gold nanoparticles onto methyl-terminated self-assembled monolayers (SAMs) on gold surface was achieved by the cooperation of hydrophobic and electrophoretic forces. Electrochemical and scanning probe microscopy techniques were utilized to explore the influence of the SAM's structure and properties of the nanoparticle/SAM/gold system. SAMs prepared from 1-decanethiol (DT) and 2-mercapto-3-n-octylthiophene (MOT) were used as hydrophobic substrates. The DT SAM is a closely packed and organized monolayer, which can effectively block the underlying gold and inhibit a variety of solution species including organic and inorganic molecules from penetrating, whereas the MOT monolayer is poorly packed or disorganized (because of a large difference in dimension between the thiophene head and the alkylchain tail) and permeable to many organic probes in aqueous solution but not to inorganic probes. Thus, the MOT monolayer provides a more energetically favorable hydrophobic surface for the penetration and adsorption of organic species than the DT monolayer. This hypothesis is supported by experiments in which the density of hydrophobically immobilized nanoparticles on the MOT SAM is much larger than that on the DT SAM. The results also suggest new approaches for modification of macroscopic surfaces with nanoscopic particles. 相似文献
949.
WANG Jun-Wen XU Fang-Bo LI Qiang-Shan SONG Hai-Bin LIU Yong-Sheng ZHANG Zheng-Zhi 《有机化学》2004,24(Z1):213
Transition metal complexes of stable N-heterocyclic carbenes have recently gained increasing attention as pre-catalysts for a number of important reactions primarily based on the analogy between N-heterocyclic carbenes and strong ó-donating tertiary phosphines,[1] Although a large number of transition-metal carbene complexes have been reported, very few incorporate chelating carbenes were reported.[2,3] Therefore, we have set out to prepare and study transition-metal compounds with chelating di-N-heterocyclic carbenes, and we now report new dicationic tetra(carbine)nickel(Ⅱ) complexes in this class (Scheme 1). Their structures have been determined by single-crystal X-ray diffraction studies (Figure 1). 相似文献
950.