Study of urinary nucleosides as biological marker in cancer patients analyzed by micellar electrokinetic capillary chromatography

Thirteen normal and modified nucleosides, primarily degradation products of transfer ribonucleic acid (tRNA), were evaluated as potential tumor markers for cancer patients. Their urinary concentrations were determined by means of micellar electrokinetic capillary chromatography (MEKC) in the urine from 54 healthy adults and 70 cancer patients, then quantitatively expressed as a function of creatinine excretion. It was found that urinary nucleosides for cancer patients were on the average significantly higher than those for healthy controls, however, no significant differences were found between male and female or between different ages. Based on 13 urinary nucleoside concentrations, principal component analysis (PCA) could be used to classify 72% of cancer patients from the healthy controls. The present study shows that the precise measurement of urinary nucleosides by MEKC in combining with PCA technique may provide a clinically useful approach for diagnosis of cancer.     

The Study of Anti-tumor Activity of Trichosanthin by Cyclic Voltammogram

IthasbeenreportedthatTrichosanthi11(TCS),isolatedfromrkiI-ilolt)ii,hasanti-tumorI-4andanti-vira1activities5-'.Someanti-tun1orremedies,whicharedesignedfromTCS,arebeingtestedanddeveloped'-.'.StudyingthebioIogicalphenomenonbyelectrochemicalmethodsisanewhotresearchspotemerginginrecentyears".Manyresultsshowedthatnotonlytheenzymesystemsuchassuccinatedehydrogenasedisplayedthediode-likebehaviorduringtheelectrontransferprocess",butalsothehigh1yorganizedorganeIle,forexample,mitochondria,andevenintac…     

Silicalite-1膜反应器中的丙烷芳构化

在丙烷芳构化反应中，氢气起着相当重要的作用；根据理论分析，消除氢气将会有利于芳构化反应的进行。在Ｓｉｌｉｃａｌｉｔｅ－１沸石分子筛膜反应器，丙烷芳构化反应中的芳烃选择性提高了１０％－２０％。针Ｓｉｌｉｃａｌｉｔｅ－ｌ膜反应器与氧化铝膜反应器中的反应结果相比较，表明膜反应器效果不仅取决于膜的渗透选择性，而且还取决于膜的渗透率。     

黄孢展齿革菌菌丝球同时吸附铅镉离子的动力学

采用间歇法，利用黄孢展齿革菌菌丝球吸附溶液中的Pb^2 和Cd^2 ，研究Pb^2 和Cd^2 共存体系中吸附初速率随初始浓度的变化规律。实验结果表明，少量Cd^2 的存在促进其对Pb^2 的吸附，并提高吸附初速率，但随着Cd^2 初始浓度的增加，促进作用逐渐减弱并转为抑制作用；Cd^2 的吸附初速率随着Pb^2 初始浓度增大而减小；Pb^2 和Cd^2 的吸附初速率都随自身初始浓度的增加而增大。     

MCM-41-supported bidentate phosphine palladium(0) complex: a highly active and recyclable catalyst for the Sonogashira reaction of aryl iodides

The first MCM-41-supported bidentate phosphine palladium(0) complex has been prepared. This complex is a highly efficient catalyst for Sonogashira reaction and can be reused at least 10 times without any decrease in activity.     

Structure of Sol-Gel-Derived Sodium Dititanate Glass

The sodium dititanate, Na₂O·2TiO₂ glass was prepared by the sol-gel method. The structure of the glass, especially local environment of Ti⁴⁺ ions was examined using X-ray diffraction and X-ray absorption fine structure (XAFS) analyses, and was compared with that of the melt-derived glass with the same composition. It was found that Ti⁴⁺ ions are rather in five-fold coordination state, forming TiO₅ pyramids with one doubly bonded Ti=O in the gel-glass, while they were in lower coordination state or four-fold coordination in the melt-derived glass.     

一类酶反应底物的光化学荧光研究

研究了对位取代酚类酶反应底物的光化学荧光反应机理，指出光子不仅可以取代过氧化物酶，而且可以取代氧化剂（Ｈ_２Ｏ_２）。用于测定多种酶反应底物，结果满意。     

中性配合物Cr(acac)_3、mer-和fac-[Cr(bza)_3]的光学拆分

本文用新方法合成了Cr(bza)_3,改进了其mer-、fac-异构体的分离方法;增大了Cr(acac)_3的化学拆分量(1.5g)。试制了DBT(二苯甲酰-d-酒石酸)吸附型手性固定相(CSP),并成功地用于色谱拆分标题配合物的对映体,mer-[Cr(bza)_3]的部分拆分是首次发现的,其他配合物的拆分结果均优于文献方法。根据mer-[Cr(bza)_3)拆分流出液前、后组分的CD光谱,指定了其对映体绝对构型。还讨论了DBT吸附型CSP的拆分效能和色谱特性。     

Na_6V_（10）O_（28）·12H_2O的合成与结构

合成并测定了十钒酸盐Ｎａ_６Ｖ_（１０）Ｏ_（２８）·１２Ｈ_２Ｏ的单晶结构。晶体属单斜晶系，Ｐ２_１／ｎ群空间，ａ＝１２．０１９（２），ｂ＝１７．１５４（２），ｃ＝１８．１７８（６），β＝１０６．２９（２）°，Ｖ＝３５７９（１），Ｍ_ｒ＝１２８７．５，Ｆ（０００）＝２５６０，μ＝２５，４４ｃｍ￣（－１），Ｚ＝４，Ｄ_ｃ＝２．３８ｇ·ｃｍ（－３）。结构由重原子法解出，全矩阵最小二乘法修正至Ｒ＝０．０６４，Ｒ_ｗ＝０．０８３。Ｖ_（１０）簇阴离子可以看成由１０个ＶＯ_６变形八面体形成，其中氧原子有４种类型：端氧、二桥氧、三桥氧和六桥氧。结果表明，阳离子相同但结晶水的数目不同时，十钒酸盐的晶系和空间群不同。     

Alkylation of Benzene with Propene over Hβ Zeolite──The Effect of Reaction Conditions on the Distribution of Products

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