Backward particle production in neutrino neon interactions

Backward proton and pion production is studied in ν and \(\bar v\) charged current interactions in neon. The results are compared with other experiments and theory. The complete backward proton data is compatible with protons produced by reinteractions in the nucleus. However in events with only one proton, muon variables appear correlated to those for the backward proton, as expected by the two-nucleon correlation model.     

Synthesis and Inclusion Properties of the Host Compound 1,3-Dihydro-1,1,3,3-tetraphenylisobenzofuran. X-Ray Crystal Structures of the Free Host and of an Inclusion Compound with 1,4-Dioxane

A novel host molecule, 1, suitable for crystalline lattice-type inclusion, has been synthesized, and its cocrystal formation ability has been investigated. Host 1 proved to be of potential use for organic solvent separation and retrieval, and a promising auxiliary for solidification of certain odorous substances. The crystal structures of the solvent-free host 1, and its complex with 1,4-dioxane (1 : 1), have been determined by single crystal X-ray diffraction. The structure of 1 (guest-free) is triclinic, P , with a = 9.452(2), b = 10.359(3), c = 13.116(3) Å, = 101.80(2), = 106.53(1) and = 104.32(1)°. The spacious, propeller-like molecules are held together by weak van der Waals' forces. The dioxane inclusion compound is monoclinic, P21/a, with a = 15.050(1), b = 8.641(1) and c = 20.658(1) Å, and = 94.56(1)°, and contains two crystallographically independent guest molecules, both located around symmetry centres. The molecular packing seems to be governed by C—H···O type bonds (C···O = 3.31 and 3.48 Å) from the host to the dioxane oxygens.     

The crystal and molecular structure of 12,13-dibromopseurotin.

The crystal structure of 12,13-dibromopseurotin has been determined by single crystal X-ray analysis. The crystals belong to space group P2₁ with a = 16.75, b = 9.63, c = 7.42 Å, β 95.9°, Z = 2. The structure was solved by the heavy atom technique and refined to R = 0.062 with 819 significant reflexions for 299 parameters.     

Aluminium(III) as a promoter of cellular oxidation

Aluminium has been known as a neurotoxic agent to experimental animals since the last century (Arch. Exp. Pharmacol. 40 (1897) 98). However, great interest arose in it bioinorganic chemistry as well biology when it was demonstrated to be the causative agent in pathologies related to the long-term dialysis treatment of uremic subjects with renal failure (Life Chem. 11 (1994) 197), and as a potential etiopathogenic cofactor for several neurodegenerative diseases. The inorganic biochemistry of aluminium is still largely to be discovered. In this review the pro-oxidative property of aluminium toward biological membrane will be presented and its implications in involvement in human pathology will be discussed in an interdisciplinary frame from the bioinorganic point of view.     

Degradation of epoxy polymers: 2—Mechanism of thermal degradation of bisphenol-A diglycidyl ether

In a previous paper, some 15 compounds were positively identified among the products of thermal degradation of bisphenol-A diglycidyl ether. The structures of an additional 22 compounds, all aromatic, were speculated upon on the basis of mass spectral analysis. In the present paper, mechanisms are proposed to account for all these products and the characteristics of their formation in the overall degradation process.     

Sensitive determination of free and plasma protein-bound dipyridamole by high-performance liquid chromatography

For many years dipyridamole (DP) has been used in the treatment of hypertension as a vasodilator, but recently it has been recognised as an anti-platelet aggregation agent and to potentiate anti-metabolite activity. A rapid and sensitive (20 nM) procedure for the determination of free and protein-bound DP in plasma, using reversed-phase high-performance liquid chromatography on an Ultrasphere XL ODS (3 microns) column (70 mm x 4.6 mm I.D.) with ultraviolet detection (280 nm), is reported. Free and bound DP were separated using ultrafiltration. Concentrations of DP between 0.1 and 10 microM were measured in plasma with a relative standard deviation of less than 9.6%. The subsequent determination of DP levels in patients orally administered 450 mg per day showed that DP binding to plasma protein is higher than 90%.