Synthesis and biological activity of new heterocyclic compounds 5-[(1,l-dimethyl)ethyl]-3-aryl-(1H-1,2,3-triazol-1-yl)-5-isoxazolidinols

In this paper new heterocyclic compounds 5-[(1,1-dimethyl)ethyl]-3-aryl-(1H-l,2,3-triazol-1-yl)-5-isoxazolodinols were obtained by the reaction of vinyl triazole derivatives with hydroxylamine hydrochloride under the action of sodium carbonate. The biological tests indicate that they had plant-growth regulating activity.     

磁多极场场参数的理论计算与分析

根据磁多极场的对称性，首先导出了磁多极场磁场分量的泰勒级数展开式，定义了磁多极场的场参数，然后根据毕奥-萨伐尔定律，导出了马鞍型磁多极场线圈的场参数理论计算公式.对各个场参数数量级的大小进行了分析，找出了场参数的递推规律，给出了场参数高阶导数的计算方法，从而能够准确计算整个空间的磁场值.还从简单单根导线计算结果过渡到多根导线或具有某种连续分布的情况. 这对于磁二极场、磁四极场、磁六极场等的应用提供了可靠的理论依据. 关键词： 磁多极场 场参数 马鞍型线圈     

大功率分布反馈激光器中光栅优化及试验

对于分布反馈激光器来说，光栅的耦合系数是一个重要参数. 利用改进的耦合波理论计算了具体器件结构中光栅形貌对二级光栅耦合系数的影响. 在此基础上制作的器件功率达到了单面50 mW，边模抑制比为36 dB. 关键词： DFB激光器 耦合波理论 二级光栅 边模抑制比     

Entanglement in a generalized Jaynes--Cummings model

We investigate the pairwise entanglement and global entanglement in a generalized Jaynes--Cummings model, which can be used to realize Greenberger--Horne--Zeilinger (GHZ) entangled state (Zheng S B 2001 {\it Phys. Rev. Lett.} {\bf 87} 230404). Our results show that the W-type entangled states cannot be generated based on the model. The dependences of entanglement on Rabi frequency $\lambda$ and dipole--dipole coupling strength ${\it \Omega}$ are given. It is found that there exists the quantum phase transition when $\lambda={\it \Omega}$. For typical experimental data, the critical temperature for pairwise entanglement is on the order of $10^{-6}$\,K. Based on these results, two strategies that overcome decoherence are proposed.     

Two Iteration Methods for Solving Linear Algebraic Systems with Low Order Matrix $A$ and High Order Matrix $B:Y=(A \otimes B)Y+\Phi$

This paper presents optimum a one-parameter iteration (OOPI) method and a multi-parameter iteration direct (MPID) method for efficiently solving linear algebraic systems with low order matrix $A$ and high order matrix $B: Y = (A \otimes B)Y+\Phi$. On parallel computers (also on serial computer) the former will be efficient, even very efficient under certain conditions, the latter will be universally very efficient.     

A reagentless electrochemiluminescent immunosensor for apurinic/apyrimidinic endonuclease 1 detection based on the new Ru(bpy)3/bi-arginine system

Apurinic/apyrimidinic endonuclease 1 (APE-1), a kind of multifunctional protein widely-distributed in the body, plays an essential role in the DNA base excision repair and serves as multiple possible roles in the response of human cancer to radiotherapy and chemotherapy. In this work, an ultrasensitive solid-state electrochemiluminescence (ECL) immunosensor is designed to determine APE-1 based on the new Ru(bpy)₃²⁺/bi-arginine system. The bi-arginine (bi-Arg) is decorated on the Au nanoparticles functionalized magnetic Fe₃O₄/reduced graphene oxide (bi-Arg/Au@Fe₃O₄–rGO) according to the self-assembling and covalent cross-linking interaction to obtain the functionalized nanocomposite of bi-Arg/Au@Fe₃O₄–rGO. Herein, the bi-Arg/Au@Fe₃O₄–rGO plays not only an amplification label to enhance the ECL signal of Ru(bpy)₃²⁺ due to the coreactant of bi-Arg but also an ideal nanocarrier to load numerous secondary antibody. Based on sandwich-type immunoassay format, this proposed method offers a linear range of 1.0 fg mL⁻¹–5.0 pg mL⁻¹ and an estimated detection limit of 0.3 fg mL⁻¹ for the APE-1. Moreover, the reagentless ECL immunosensor also exhibits high sensitivity, excellent selectivity and good stability, which has greatly potential development and application in clinical diagnostics, immunology and biomedical research.     

Orlicz空间中加权光滑模与K-泛函的等价性及其应用

首先介绍了由Young函数生成的Orlicz空间L_Φ~*[0,∞),然后利用归纳假设和分解方法证明了r阶加权光滑模与加权K-泛函的等价性,最后作为光滑模的应用给出了Gamma算子在L_Φ~*[0,∞)空间内加权同时逼近的B-型强逆不等式.     

Quantum correlations in spin models

Bell nonlocality, entanglement and nonclassical correlations are different aspects of quantum correlations for a given state. There are many methods to measure nonclassical correlations. In this paper, nonclassical correlations in two-qubit spin models are measured by the use of measurement-induced disturbance (MID) [S. Luo, Phys. Rev. A 77 (2008) 022301] and geometric measure of quantum discord (GQD) [B. Daki?, V. Vedral, C. Brukner, Phys. Rev. Lett. 105 (2010) 190502]. Their dependences on external magnetic field, spin–spin coupling, and the Dzyaloshinskii–Moriya (DM) interaction are presented in detail. We also compare Bell nonlocality, entanglement measured by concurrence, MID and GQD and illustrate their different characteristics.     

Reversible two-photon photoswitching and two-photon imaging of immunofunctionalized nanoparticles targeted to cancer cells

Both photoswitchable fluorescent nanoparticles and photoactivatable fluorescent proteins have been used for super-resolution far-field imaging on the nanometer scale, but the photoactivating wavelength for such photochemical events generally falls in the near-UV (NUV) region (<420 nm), which is not preferred in cellular imaging. However, using two near-IR (NIR) photons that are lower in energy, we can circumvent such problems and replace NUV single-photon excitations (e.g., 390 nm) with NIR two-photon excitations (e.g., 780 nm). Thus, we have demonstrated that alternating 780 nm NIR two-photon and 488 nm single-photon excitations induces reversible on-off fluorescence switching of immunotargeted nanoparticles in the human breast cancer cell line SK-BR-3. Herein, two-photon absorption not only caused spiropyran-merocyanine photoisomerization within the particles but also imparted red fluorescence. In comparison with single-photon NUV excitations, two-photon NIR laser excitations can potentially reduce absorption-related photodamage to living systems because cellular systems absorb much more weakly in the NIR.     

两个由双咪唑基配体构筑的锰、镉配合物的合成及晶体结构(英文)

通过水热法合成了2个金属-有机配位聚合物[Mn(dipha)(1,3-bix)]n·nH2O(1)和[Cd2(NIPH)2(bimb)2.5(H2O)]n·3nH2O(2)(H2dipha=2,2′-联苯二甲酸,1,3-bix=1,3-双(咪唑基-1-甲基)-苯,H2NIPH=5-硝基间苯二甲酸,bimb=1,4-双(咪唑基-1-甲基)-丁烷)。并对其进行了元素分析、红外光谱、热重和X-射线单晶衍射测定。这2个配合物通过氢键和π-π相互作用形成了超分子网状结构。此外还研究了配合物2的荧光性质。