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231.
Maria Rosaria Lancia Umberto Mosco 《Journal of Mathematical Analysis and Applications》2008,347(1):354-369
The aim of this work is to obtain convergence results for the solutions of transmission problems across highly conductive layers of pre-fractal type from the point of view of homogenization. We prove the M-convergence of the energy functionals to an energy functional which incorporates a singular term, supported within the layer. From the convergence of the energy functionals we deduce the convergence of the approximating solutions to the limit solution in a suitable sense. 相似文献
232.
Vincenzo De Sio Maria Rosaria Acocella Rosaria Villano Arrigo Scettri 《Tetrahedron: Asymmetry》2010,21(11-12):1432-1435
Chiral 2-methylsulfinyl benzaldehyde proved to be a valuable starting material for a convenient approach towards a variety of imino- and amino-sulfoxides. The catalytic properties of these new ligands, as potential activators of allyl trichlorosilane, have been exploited in new catalytic procedures for the synthesis of enantioenriched homoallylic alcohols. 相似文献
233.
[4+2] Cycloaddition of singlet oxygen to suitably substituted furans followed by reduction of the corresponding endoperoxides afforded functionalized enediones which quickly cyclized into the titled spiroketals. The reported method represents a green synthetic one-pot procedure for novel [6,6]-, [5,6]-, and [5,5]-spiroketals of sugars. 相似文献
234.
235.
236.
Dye-sensitized photooxygenation of 2-methyl 5-(2,3,5-tri-O-acetyl-β-d-ribofuranosyl)furoate leads to (1S,4R)-endo-peroxide, highlighting a high facial diastereoselectivity. This endo-peroxide rearranges into syn-(1R,2R:3S,4R)-diepoxide C-nucleoside, while by Et2S-reduction followed by NEt3 catalysis affords a spirocyclic C-nucleoside. 相似文献
237.
Duce C Ghezzi L Onor M Bonaduce I Colombini MP Tine' MR Bramanti E 《Analytical and bioanalytical chemistry》2012,402(6):2183-2193
In this work, we characterized paint reconstructions using ovalbumin and casein as binders, and cinnabar (HgS) as a pigment,
before and after artificial ageing. Egg and casein are common paint binders that were used historically in the technique of
tempera painting. Despite extensive research on the identification of proteinaceous binders in paintings, there is a substantial
lack of knowledge regarding the ageing pathway of their protein content, and their chemical interaction with inorganic pigments.
Thermogravimetric analysis, infrared spectroscopy and size-exclusion chromatography (SEC) were used to reveal the physico-chemical
processes involved in the ageing of proteins in paintings. Taken together, the three techniques highlighted that proteins
are subject to both cross-linking and hydrolysis upon ageing, and to a lesser extent, to oxidation of the side chains. Mercury–protein
interactions were also revealed using a cold vapour generation atomic fluorescence spectrometer mercury-specific detector
coupled to SEC. The study clearly showed that HgS forms stable complexes with proteins and acts as a sensitizer in cross-linking,
hydrolysis and oxidation. 相似文献
238.
Hussin N Mondello L Costa R Dugo P Yusoff NI Yarmo MA AbWahab A Said M 《Natural product communications》2012,7(7):927-930
Patchouli essential oil can be obtained from fresh, dried and fermented plant material. It is a highly valuable product in the fragrance industry and its quality changes depending upon raw material age and oil storage. In this work, patchouli essential oils derived from different treatments have been subjected to GC-FID quantitative analysis using an internal standard (ISTD) method with response factors (RF). Samples were obtained from i) fresh plants; ii) hydrodistillation of one year mature and fermented plants; iii) hydrodistillation of one year mature plants; iv) commercial products from Indonesia and Malaysia. Linear Retention Indices (LRI) for both polar and non-polar GC-MS analyses were also measured as a tool for qualitative analysis towards a homologous series of C7-C30 n-alkanes. The results obtained confirmed that, in all samples, patchouli alcohol was the main volatile constituent, with higher amount in lab-scale produced oils, compared with commercial samples. Other major compounds, in lab oils and commercial samples respectively, were: delta-guaiene, alpha-guaiene, pogostol, seychellene and alpha-patchoulene. Another 36 compounds were also found. 相似文献
239.
Santoro AM Lo Giudice MC D'Urso A Lauceri R Purrello R Milardi D 《Journal of the American Chemical Society》2012,134(25):10451-10457
The aim of this study is to verify if water-soluble porphyrins can be used as proteasome inhibitors. We have found that cationic porphyrins inhibit proteasome peptidase activities much more effectively than the corresponding anionic derivatives. The relevance of electrostatics in driving porphyin-proteasome interactions has been confirmed by the observation that the inhibitory efficiency of the cationic macrocycles decreases with the number of positive substituents. We have also investigated various metalloporphyrins, which differ due to the different propension of the central metal ion toward axial coordination. Our experimental results indicate that the naked cationic porphyrins are the most active in reversibly inhibiting the three main protease activities of the proteasome in the micromolar range. A spectroscopic characterization of porphyrin-proteasome interactions by UV-vis spectra parallels the results of inhibition assays: the higher the inhibitory effect the stronger the spectroscopic variations are. To interpret the action of porphyrins at a molecular level, we have performed calculations evidencing that cationic porphyrins may hinder the access to the canonical proteolytic site on the proteasome β5 subunit. In particular, an inspection of the top-scoring docking modes shows that the tetracationic porphyrin blocks the catalytic pocket, close to the N termini of the β5 proteasome subunit, more efficiently than its anionic counterpart. Proteasome inhibition activity of porphyrins unites their known anticancer properties making them suitable as a scaffold for the design of novel multitargeted molecules. 相似文献
240.
For the solution of linear discrete ill-posed problems, in this paper we consider the Arnoldi-Tikhonov method coupled with the Generalized Cross Validation for the computation of the regularization parameter at each iteration. We study the convergence behavior of the Arnoldi method and its properties for the approximation of the (generalized) singular values, under the hypothesis that Picard condition is satisfied. Numerical experiments on classical test problems and on image restoration are presented. 相似文献