Asymptotic Information-Theoretic Detection of Dynamical Organization in Complex Systems

The identification of emergent structures in complex dynamical systems is a formidable challenge. We propose a computationally efficient methodology to address such a challenge, based on modeling the state of the system as a set of random variables. Specifically, we present a sieving algorithm to navigate the huge space of all subsets of variables and compare them in terms of a simple index that can be computed without resorting to simulations. We obtain such a simple index by studying the asymptotic distribution of an information-theoretic measure of coordination among variables, when there is no coordination at all, which allows us to fairly compare subsets of variables having different cardinalities. We show that increasing the number of observations allows the identification of larger and larger subsets. As an example of relevant application, we make use of a paradigmatic case regarding the identification of groups in autocatalytic sets of reactions, a chemical situation related to the origin of life problem.     

Super-accelerating bouncing cosmology in asymptotically free non-local gravity

Application of the effective action approach to amplitudes with loop integration is studied for collisions on two and three centers with possible gluon emission. A rule is formulated for the integration around pole singularities in the induced vertices which brings the results in agreement with the QCD. It is demonstrated that the amplitudes can be restored from the purely transverse picture by introducing the standard Feynman propagators for intermediate gluons and quarks.     

Exploitation of the Fiber Capacity in Optical Networks Using Time, Frequency, and Space Division Multiple Accesses

In this work we investigate how to obtain very high capacity transmissions in optical networks taking into account the limitations due to the physical channel. We consider both the case in which all the users are connected by a star coupler and the case in which the users are directly connected by the network topology. As a reference, we consider a ring network and a Shuffle Multihop Network (SMN). The use of optical systems to implement high-capacity networks is numerically investi gated by means of numerical simulations taking into consideration the channel limitations due to the chromatic dispersion, the Kerr effect, and the amplified spontaneous emission (ASE) noise of the optical amplifiers. In our model, we consider that the signal, during the routing process that is performed at the user position, undergoes only an attenuation. We suppose the use of intensity modulated signals and receivers with direct detection. Packet switching and digital transmission are assumed with soliton and conventional nonreturn to zero signals. Both wave length and time division multiple accesses are considered. The results show that, in the case of the Time Division Multiple Access (TDMA) technique, the use of a star coupler to connect the users reduces the capacity of a network with respect to the case in which a direct connection of the users is used. This is due to the strong power fluctuations that are present during the signal propagation and to the large quantity of accumulated ASE noise. On the other hand, the use of a star coupler shows the advantage to being easily reconfigurable. The Wavelength Divison Multiple Access (WDMA) technique permits us to achieve higher capacities with respect to the TDMA. This is due to the fact that in the propagation conditions, due to the presence of a star coupler, high bit rate signals are strongly degraded. On the other hand, several low bit rate signals operating at different wavelengths can propagate with a low power level, avoiding strong degradation due to the Four Wave Mixing (FWM) effect. Among the topologies considered in this work, the SMN is the one that generally permits us to reach the highest throughput because in the SMN the signal hops in a limited number of Network Interface Units (NIUs) before reaching the final destination.     

Generation and intramolecular reactivity of acyl radicals from alkynylthiol esters under reducing tin-free conditions

[reaction: see text] The radical chain reaction of benzenethiol with alkynylthiol esters provides a new, valuable protocol for the tin-free generation of acyl radicals that arise from intramolecular substitution at sulfur by the initial sulfanylvinyl radicals.     

Production of Mesoglycan/PCL Based Composites through Supercritical Impregnation

The development of targeted therapies for wound repair is knowing a growing interest due to the increasing aging of the population and the incidence of chronic pathologies, mainly pressure ulcers. Among molecules recruiting cell populations and promoting the formation of new vital tissue, sodium mesoglycan (MSG) has been proven to be effective in wound healing. In this work, MSG impregnation of polymer matrices has been attempted by a supercritical carbon dioxide-based process. Polymeric matrices are composed of polycaprolactone blends, where water-soluble polymers, polyethylene glycol, polyvinyl pyrrolidone, gelatin, and thermoplastic starch, have been employed to modulate the MSG release, making the devices potentially suitable for topical administrations. Two different techniques have been used to obtain the films: the first one is compression molding, producing compact and continuous structures, and the second one is electrospinning, producing membrane-like designs. A higher amount of MSG can be loaded into the polymeric matrix in the membrane-like structures since, in these films, the impregnation process is faster than in the case of compression molded films, where the carbon dioxide has firstly diffused and then released the active molecule. The type of water-soluble polymer influences the drug release rate: the blend polycaprolactone-gelatin gives a prolonged release potentially suitable for topical administration.     

Multi-component, regio-selective aldol addition of β-ketoesters to aldehydes: scope and applications

Simple and effective multi-component one-pot aldol addition/protection reactions of β-ketoesters to a series of aldehydes in the presence Me(3)SiCl and i-Pr(2)EtN have been described. The analysis of the scope of the reaction revealed a dramatic dependence of the reactivity on the substrates used. Thus the effect of a catalytic amount of DMF and different reaction conditions was widely investigated. Further transformations of the aldol adducts were particularly useful to give valuable diols and compounds with quaternary stereocenters, while X-ray structural analysis gave also important stereochemical information about this challenging reaction.     

Poly(ethylene glycol)-supported tetrahydroxyphenyl porphyrin: a convenient,recyclable catalyst for photooxidation reactions

[reaction: see text] A new poly(ethylene glycol)-supported porphyrin has been prepared and its ability as a promoter in photooxidation reactions has been studied. The PEG-supported catalyst exhibits high activity, comparable to that of a nonanchored sensitizer, and it is easily removable by filtration from the reaction mixture. The polymer-bound porphyrin has been recycled up to six times with no loss of chemical and stereochemical efficiency.