Quantum Teleportation and Beam Splitting

Following the previous paper in which quantum teleportation is rigorously discussed with coherent entangled states given by beam splittings, we further discuss two types of models, the perfect teleportation model and non-perfect teleportation model, in a general scheme. Then the difference among several models, i.e., the perfect models and the non-perfect models, is studied. Our teleportation models are constructed by means of coherent states in some Fock space with counting measures, so that our model can be treated in the frame of usual optical communication. Received: 1 February 2001 / Accepted 19 July 2001     

The dehydration behavior of nafagrel hydrochloride hydrates

Nafagrel hydrochloride has two kinds of stable pseudopolymorphs such as hemihydrate and monohydrate. The dehydration of crystal water of these hydrates took place in one step under nitrogen gas atmosphere, whereas the two dehydration steps could be detected for the monohydrate under self-generated atmosphere such as the quasi-sealed and/or the completely sealed systems. These observations indicated that the crystal water of the monohydrate consisted of two different crystal waters. Prediction of the stability for the hydrates using the kinetic parameters indicated that the dehydration of the monohydrate occurred faster than that of the hemihydrate.     

Synthesis and antifungal activities of R-102557 and related dioxane-triazole derivatives

Novel triazole compounds with a dioxane ring were synthesized. Condensation of the diol precursor 10 with various aromatic aldehydes 11-13 under acidic conditions afforded a series of dioxane-triazole compounds 14-16. The antifungal activities of the compounds 14-16 were evaluated in vivo in mice infection models against Candida and Aspergillus species. High activities were seen for the derivatives with one or two double bond(s) and an aromatic ring substituted with an electron-withdrawing group in the side chain. Among the derivatives, R-102557 (16R: Ar=4-(2,2,3,3-tetrafluoropropoxy)phenyl) showed excellent in vivo activities against Candida, Aspergillus and Cryptococcus species. It also showed high tolerance in a preliminary toxicity study in rats.     

Preparation and Characterization of Titania Thin Films from Aqueous Solutions

Dip- or spin-coating and characterization of titania (TiO₂) thin films from various aqueous solutions have been studied. The aqueous titanium solutions mainly used in this study were halogen- and chelate-free solutions with the concentrations up to 1.4 M derived from titanium isopropoxide (TIP) with tetramethylammonium hydroxide (TMAOH) or some alkylamines, while aqueous and alcoholic solutions containing titanium atoms stabilized chelating ligands were examined for comparison. The TiO₂ films prepared from the TIP-TMAOH solution were already crystallized at 350°C to anatase form and those formed at 600°C had high transparency and refractive indices of 2.40. No carbon residue in the film prepared at 400°C was detected by XPS. The pure anatase form was sustained up to 850°C. Interestingly, it was found that the (004) preferentially oriented anatase films were obtained from TIP-lactic acid (LA) system until 700°C. The solutions containing citric acid (CA) or alkanolamines yielded anatase and rutile form fired at the temperatures equal to or higher than 600°C. Carbon residue was detected in the film fired at 400°C. The film thickness monotonically decreased from the upper to the bottom ends of the substrate. However, it was found that the thickness uniformity was drastically improved by an addition of sucrose to the aqueous solutions. The effects of the solution composition and polyhydroxy compounds on the crystal modifications of formed films and the film uniformity are discussed.     

Synthesis and antitumor activity of 6-O-carboxymethyl chitin fixing 5-fluorouracils through pentamethylene, monomethylene spacer groups via amide, ester bonds.

In order to provide the water-soluble and biodegradable macromolecular prodrug of 5-fluorouracil (5FU), the fixation of 5FUs to 6-O-carboxymethyl chitin(CM-chitin) through pentamethylene, monomethylene spacer groups via amide, ester bonds was carried out. The obtained CM-chitin/5FU conjugate showed the slow release of 5FU and exhibited remarkable antitumor activity against P388 lymphocytic leukemia in mice by intraperitoneal(i.p.) implantation/i.p. injection.     

High pressure Raman study of bromine and iodine: soft phonon in the incommensurate phase

A new phase of solid bromine was discovered at a pressure region above 80 GPa by Raman scattering experiments with a diamond anvil high-pressure cell. This phase was found to be the same as the iodine phase V with an incommensurate structure [Nature (London) 423, 971 (2003)] which appears between the molecular phase I and the monatomic phase II. In the incommensurate phases of both bromine and iodine, Raman active soft modes were clearly found in the low frequency region. The data suggest that the monoatomic phase II occurs above 30 and 115 GPa for iodine and bromine, respectively.     

Syntheses of 2-(3,4-dimethoxyphenyl)ethylamine derivatives and their antiulcer activities.

A series of acyl derivatives of 2-(3,4-dimethoxyphenyl)ethylamine (4) were synthesized and evaluated for their effectiveness to prevent water-immersion stress-induced gastric ulceration when given intraperitoneally to rats. Among them N-[2-(3,4-dimethoxyphenyl)ethyl]-2-phenylaminoacetamide hydrochloride (15) had significant antiulcer activity. Further modification of the four parts of 15 revealed that only the introduction of a carbamoyl group into 2- or 3-position of the phenylamino part gave compounds (49-51, 54 and 55) which retained antiulcer activity comparable to the lead compound. However, the compounds (49-51 and 54) did not exert a prophylactic effect when administered orally except for the 3-substituted bezamide derivative 55. Alkyl substitution on the nitrogen of benzamide gave 3-[[[2-(3,4-dimethoxyphenyl)ethyl]carbamoyl]methyl] amino-N-methylbenzamide (66, DQ-2511) and the related compounds (67, 70, 74 and 77) which all had potent antiulcer activities at oral doses of 50-400 mg/kg.     

Knight Shift of 90Nb, 93mMo, 96Tc,and 101mRh in Nb Using Brute-Force NMRON

Brute-force nuclear magnetic resonance on oriented nuclei (BF-NMRON) of ⁹⁰Nb, ^93mMo, ⁹⁶Tc, and ^101mRh was carried out in a new host metal, Nb. The resonance center frequencies at an external field of 11.922(6) T were obtained as ν(⁹⁰NbNb) = 56.572(9) MHz, ν(^93mMoNb) = 85.76(3) MHz, ν(⁹⁶TcNb) = 66.997(11) MHz, and ν(^101mRh Nb) = 111.010(19) MHz. A systematic analysis of the Knight shift of 4d elements in extremely dilute alloy systems is briefly discussed. This revised version was published online in September 2006 with corrections to the Cover Date.