双面碎片的英文文件复原方法研究

对英文材料的双面规则碎片文件复原问题进行了研究.由于碎片边界是规则的几何形状,无法采用几何形状匹配算法进行复原,为此提出了基于碎片边缘像素特征的匹配复原算法,建立了双面二维灰度匹配数学模型.通过加入行约束条件,减少横向匹配中的纵向误差,并通过消除列匹配中的误差,优化了匹配算法.该模型可以实现块状双面英文碎片的完整复原.     

PMMA-b-QPDMAEMA的合成及其抗菌活性

以α-溴代丙酸乙酯为引发剂,CuCl/二乙烯三胺为催化剂,采用ATRP法制得5个不同分子量的聚甲基丙烯酸甲酯-聚甲基丙烯酸二甲氨乙酯嵌段共聚物(PMMA-b-PDMAEMA, P¹~P⁵); P¹~P⁵经溴代辛烷季铵化合成了5个聚季铵盐(Q¹~Q⁵),其结构和性能经¹H NMR, FT-IR, GPC和DSC表征。结果表明：P⁴和Q⁴的玻璃化转变温度分别为109.67 ℃和117.95 ℃。采用平板活菌计数法研究了Q¹~Q⁵对金黄色葡萄球菌(S. aureus)和大肠杆菌(E. coli)的抗菌活性。结果表明：Q¹~Q⁵对S. aureus的抗菌活性优于E. coli,其MIC值分别为300 mg·L^-1, 250 mg·L^-1, 275 mg·L^-1, 225 mg·L^-1和150 mg·L^-1。     

MTV-G experiment: Probing non-standard strong gravitational field at nuclear scale using geodetic precession

A new experiment named MTV-G, probing a large electron spin-precession due to a possible strong gravitational field, which predicted by large extra dimension model, is started at TRIUMF from 2011. In an electron-nuclear scattering experiment, a strong gravitational field is tested as a large spin precession effect caused by geodetic precession predicted by general relativity theory as a result of a warped space-time around nuclei. Experimental design using spin polarized electron source and Mott-spin analyzer, commissioning experiment and the preliminary results are described.     

Changes in diffusion tensor imaging (DTI) eigenvalues of skeletal muscle due to hybrid exercise training

Several studies have proposed the cell membrane as the main water diffusion restricting factor in the skeletal muscle cell. We sought to establish whether a particular form of exercise training (which is likely to affect only intracellular components) could affect water diffusion. The purpose of this study is to characterise prospectively the changes in diffusion tensor imaging (DTI) eigenvalues of thigh muscle resulting from hybrid training (HYBT) in patients with non-alcoholic fatty liver disease (NAFLD). Twenty-one NAFLD patients underwent HYBT for 30 minutes per day, twice a week for 6 months. Patients were scanned using DTI of the thigh pre- and post-HYBT. Fractional anisotropy (FA), apparent diffusion coefficient (ADC), the three eigenvalues lambda 1 (λ1), λ2, λ3, and the maximal cross sectional area (CSA) were measured in bilateral thigh muscles: knee flexors (biceps femoris (BF), semitendinosus (ST), semimembranous (SM)) and knee extensors (medial vastus (MV), intermediate vastus (IV), lateral vastus (LV), and rectus femoris (RF)), and compared pre- and post-HYBT by paired t-test. Muscle strength of extensors (P < 0.01), but not flexors, increased significantly post-HYBT. For FA, ADC and eigenvalues, the overall picture was of increase. Some (P < 0.05 in λ2 and P < 0.01 in λ1) eigenvalues of flexors and all (λ1-λ3) eigenvalues of extensors increased significantly (P < 0.01) post-HYBT. HYBT increased all 3 eigenvalues. We suggest this might be caused by enlargement of muscle intracellular space.     

Mn12-Ac磁性分子团簇单晶的热重-差热分析与结构转变

通过热重-差热分析(TG-DTA)，考察了Mn12-Ac磁性分子晶体从室温到270℃的热失重过程.结合x射线粉末衍射分析，认为在第一个失重阶段，即25—110℃，Mn12-Ac失去了处于团簇分子间隙的结晶乙酸和结晶水，同时失去了团簇分子中与4个Mn3+配位的4个H2O，Mn12-Ac单晶结构被破坏，但是团簇分子的基本结构依然存在；在第二个失重阶段，即180—230℃，Mn12-Ac转变为γ-Mn2O3，其中混有少量Mn3O4. 关键词： Mn12 分子团簇 热重-差热分析 x射线衍射     

Stabilization of atmospheric carbon dioxide via zero emissions-An alternative way to a stable global environment. Part 1: Examination of the traditional stabilization concept

The concept of "stabilization" of atmospheric CO2 concentration is re-examined in connection with climate-change mitigation strategies. A new "zero-emissions stabilization (Z-stabilization)" is proposed, where CO2 emissions are reduced to zero at some time and thereafter the concentration is decreased by natural removal processes, eventually reaching an equilibrated stable state. Simplified climate experiments show that, under Z-stabilization, considerably larger emissions are permissible in the near future compared with traditional stabilization, with the same constraint on temperature rise. Over longer time scales, the concentration and temperature decrease close to their equilibrium values, much lower than those under traditional stabilization. The smaller temperature rise at final state is essential to avoid longer-term risk of sea level rise, a significant concern under traditional stabilization. Because of these advantages a Z-stabilization pathway can be a candidate of practical mitigation strategies as treated in Part 2.(Contributed by Taroh MATSUNO, M.J.A.).     

Suppressed speckle contrast of blue light emission out of white lamp with phosphors excited by blue laser diodes for high-brightness lighting applications

The speckle contrast of blue light emission out of high-brightness white lamps using phosphors excited by InGaN/GaN blue laser diodes is evaluated as a measure of coherence. As a result, speckle contrast of as low as 1.7%, the same level as a blue light emitting diode, is obtained. This implies that the original blue laser light can be converted into incoherent light through lamp structures without any dynamic mechanisms. This unique speckle-free performance is considered to be realized by multiple scattering inside the lamp structure, the multi-longitudinal mode operation of the blue laser diodes, and the use of multiple laser diodes. Such almost-incoherent white lamps can be applied for general lighting without any nuisance of speckle noise and should be categorized as lamps rather than lasers in terms of laser safety regulation.     

meso-Arylporpholactones and their Reduction Products

The rational syntheses of meso-tetraaryl-3-oxo-2-oxaporphyrins 5, known as porpholactones, via MnO(4)(-)-mediated oxidations of the corresponding meso-tetraaryl-2,3-dihydroxychlorins (7) is detailed. Since chlorin 7 is prepared from the parent porphyrin 1, this amounts to a 2-step replacement of a pyrrole moiety in 1 by an oxazolone moiety. The stepwise reduction of the porpholactone 5 results in the formation of chlorin analogues, meso-tetraaryl-3-hydroxy-2-oxachlorin (11) and meso-tetraaryl-2-oxachlorins (12). The reactivity of 11 with respect to nucleophilic substitution by O-, N-, and S-nucleophiles is described. The profound photophysical consequences of the formal replacement of a pyrrole with an oxazolone (porphyrin-like chromophore) or (substituted) oxazole moiety (chlorin-like chromophore with, for the parent oxazolochlorin 12, red-shifted Q(x) band with enhanced oscillator strengths) are detailed and rationalized on the basis of SAC-CI and MNDO-PSDCI molecular orbital theory calculations. The single crystal X-ray structures of the porpholactones point at a minor steric interaction between the carbonyl oxygen and the flanking phenyl group. The essentially planar structures of all chromophores in all oxidation states prove that the observed optical properties originate from the intrinsic electronic properties of the chromophores and are not subject to conformational modulation.     

Simple and rapid HPLC-UV method using an ultrafine particle octadecylsilane for determination of residual fentanyl in applied Durotep MT transdermal matrix patches and its clinical application

A few complicated and time-consuming methods are available for the determination of residual fentanyl in Durotep MT transdermal patches, however, their application to clinical settings is limited. The aim of this study was to develop a simple and rapid HPLC-UV method using an ultrafine particle octadecylsilane (ODS) for the determination of residual fentanyl in applied Durotep MT transdermal matrix patches. Patch extraction involved sonicating a shredded Durotep MT patch in acetonitrile for 15 min. Fentanyl separation was completed within 2 min using a 2.3-μm particle ODS column (50 × 4.6 mm i.d.) at a flow rate of 1.5 mL/min. No peaks interfering with fentanyl (1.27 min) and papaverine (0.89 min) as an internal standard were observed. The calibration curve for fentanyl was linear over the range of 0.015-9.0 mg as a Durotep MT patch. The intra- and inter-assay precisions and accuracies of each patch were within 5.3% and 103.9-110.5% and within 8.2% and 97.1-104.3%, respectively. The validated method was applied to determine residual fentanyl in Durotep MT patches used in 35 cancer patients. Although the plasma fentanyl concentration was significantly correlated with its measured absorption rate, the measured absorption rate normalized fentanyl concentration showed a large inter-individual variation. The validated simple and rapid HPLC-UV method established in the present study is helpful for evaluating the absorption rate of fentanyl in patients receiving Durotep MT patches.     

西安地区活动断裂活动性的Fuzzy Grey模式评价

应用计算流体动力学方法对人体在循环呼吸模式下口喉模型内的气流运动特性进行数值模 拟,分析了循环呼吸模式下口喉模型内的气流组织形式以及气流运动对呼吸道壁面以及气溶 胶运动沉积的影响. 吸气阶段,在咽部外壁和声门下游气管上部外壁气流发生分离,形成分 离区. 呼气阶段,分别在咽部外壁和喉部外壁形成高速区. 循环呼吸模式下,咽部、喉部与 气管内的高轴向速度区和二次涡流运动均是在呼吸过程中间歇性的产生,形成的高剪应力区 也是间歇性的. 壁面受到的剪应力周期性地改变方向,引起壁面劳损和组织损伤的可能性增 大,同时在这些部位容易造成气溶胶的沉积.