Analysis of Non-normal Operators via Aluthge Transformation

Let T be a bounded linear operator on a complex Hilbert space . In this paper, we show that T has Bishops property () if and only if its Aluthge transformation has property (). As applications, we can obtain the following results. Every w-hyponormal operator has property (). Quasi-similar w-hyponormal operators have equal spectra and equal essential spectra. Moreover, in the last section, we consider Chs problem that whether the semi-hyponormality of T implies the spectral mapping theorem Re(T) = (Re T) or not.     

Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as a factor Xa inhibitor II. Substituent effect on biological activities

Intravascular clot formation is an important event in a number of cardiovascular diseases. The prevention of blood coagulation has become a major target for new therapeutic agents. Factor Xa (FXa) is a trypsin-like serine protease that plays a key role in the blood coagulation cascade and represents an attractive target for anticoagulant drug development. We have investigated substituents in the central part of a lead compound (3: M55113), and discovered that compound M55551 (34: (R)-4-[(6-Chloro-2-naphthalenyl)sulfonyl]-6-oxo-1-[[1-(4-pyridinyl)-4-piperidinyl]methyl]-2-piperazinecarboxylic acid) is a potent inhibitor of FXa (IC(50)=0.006 microM), with high selectivity for FXa over trypsin and thrombin. The activity of this compound is ten times more powerful than the lead compound.     

Two-Dimensional Optical Data Transmission with Space-Time Conversion Combined with Code Division Multiple Access

A new scheme for two-dimensional parallel data transmission with a femtosecond laser pulse through a single-mode fiber, which is based upon one-dimensional space-time conversion technique in conjunction with code division multiple access (CDMA), is implemented and numerically demonstrated. Since many one-dimensional spatial data, which are encoded with their own M-sequence code, must be embedded in a single pulse, the bit-error rate performance degrades compared with conventional CDMA driven by many unsynchronized pulses. Still, two-dimensional digital images in a 16 bits × 16 bits plane (256-bits parallel data) are successfully transmitted by a single femtosecond laser pulse at an equivalent transmission rate of 1.6 Tbit/s and recovered by spectral holography.     

Gel formation with multiple interunit junctions. I—Molecules carrying different functional groups

Number‐ and weight‐average molecular weight of condensation polymers formed by primary molecules carrying different species of functional groups {A_i} (i = 1, 2, …, s) are derived by cascade theory. These functional groups are allowed to form multiple junctions of variable multiplicity k. The gel point condition is found to be given by ∑ w_i/|μ_w,i + 1/∑ f_i ? 1 = 0, where f_i is the number of A_i groups specified by the index i on a primary molecule, w_i ≡ f_i/∑ f_i the number fraction of the species i it carries, and |μ_w,i the weight average multiplicity of the junctions formed by the groups A_i. The explicit form of the molecular weight distribution function is found for the simplest case of two components. Possible application to thermoreversible gelation is suggested. © 2003 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 41: 2405–2412, 2003     

High-density DNA alignment on an Au(111) surface starting from folded DNA

High-density uniform DNA alignment on a metal substrate is essential for creating sensitive DNA devices. We develop a self-sensing DNA alignment process starting from folded DNA to achieve high-density, uniform DNA alignment on an Au(111) surface. We demonstrate that folded DNA plays a critical role in avoiding DNA aggregation and distributing the DNA uniformly on an Au(111) surface at the greatest density and quality ever attained. We also verify that the distributed, folded DNA can be stimulated to align only when the appropriate buffer flow is applied. This selective self-sensing DNA alignment on an Au surface will be a key technology for creating dynamic DNA sensors and switches.     

Hydrogen-induced Sulfur Vacancies on the MoS2 Basal Plane Studied by Ambient Pressure XPS and DFT Calculations

Sulfur vacancy on an MoS₂ basal plane plays a crucial role in device performance and catalytic activity; thus, an understanding of the electronic states of sulfur vacancies is still an important issue. We investigate the electronic states on an MoS₂ basal plane by ambient-pressure X-ray photoelectron spectroscopy (AP-XPS) and density functional theory calculations while heating the system in hydrogen. The AP-XPS results show a decrease in the intensity ratio of S 2p to Mo 3d, indicating that sulfur vacancies are formed. Furthermore, low-energy components are observed in Mo 3d and S 2p spectra. To understand the changes in the electronic states induced by sulfur vacancy formation at the atomic scale, we calculate the core-level binding energies for the model vacancy surfaces. The calculated shifts for Mo 3d and S 2p with the formation of sulfur vacancy are consistent with the experimentally observed binding energy shifts. Mulliken charge analysis indicates that this is caused by an increase in the electronic density associated with the Mo and S atoms around the sulfur vacancy as compared to the pristine surface. The present investigation provides a guideline for sulfur vacancy engineering.     

Preparation of cyanoacrylate nanoparticles using monosaccharides or disaccharides

By using biomaterials, including monosaccharides and disaccharides, as polymeric stabilizing agents, the cyanoacrylate nanoparticles was prepared respectively, with particles diameter of approximately 200 nm or 300 nm. The new method was applied to load/encapsulate ampicillin (ABPC) and pDNA into nanoparticles. Loading efficiency of ABPC was increased compared to the existing method in which dextran is used as a stabilizer. The pDNA encapusulation rate was 68.7%, by using glucose.