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A.A. Kamel CM. Ma M.S. El-Aasser F.J. Micale J.W. Vanderhoff 《Journal of Dispersion Science and Technology》2013,34(2-3):315-330
The electrophoretic mobility behavior of well-characterized polystyrene latex particles, carrying one type of surface functional endgroups, has been studied as a function of pH. At low pH, the interaction of protons with the functional endgroups increased in the order: Hydroxyl > carboxyl > sulfate; at high pH the order of interaction was reversed; and at intermediate pH no interactions were observed. The particles of the polystyrene latexes in their different forms at the intermediate pH range, dispersed in deionized water, all exhibited the same mobility irrespective of the functional endgroup. The origin of charge in these systems is explained as being the result of either the preferential adsorption of hydroxyl ions or an electron - injection mechanism due to the overlap of local intrinsic molecular - ion states in polystyrene and water. At low concentrations of functional endgroups, the surface properties of the polystyrene latexes are largely dependent upon the hydrophobic nature of the surface. 相似文献
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Corticosteroid hormone-induced factor (CHIF) is a major regulatory subunit of the Na,K-ATPase, and a member of an evolutionarily conserved family of membrane proteins that regulate the function of the enzyme complex in a tissue-specific and physiological-state-specific manner. Here we present the structure of CHIF oriented in the membrane, determined by solid-state NMR orientation-dependent restraints. Because CHIF adopts a similar structure in lipid micelles and bilayers, it is possible to assign the solid-state NMR spectrum measured for (15)N-labeled CHIF in oriented bilayers from the structure determined in micelles, to obtain the global orientation of the protein in the membrane. 相似文献
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Tobias Frank Johannes CM Schlachetzki Bettina G?ricke Katrin Meuer Gundula Rohde Gunnar PH Dietz Mathias B?hr Armin Schneider Jochen H Weishaupt 《BMC neuroscience》2009,10(1):49-10
Background
The hematopoietic Granulocyte-Colony Stimulating Factor (G-CSF) plays a crucial role in controlling the number of neutrophil progenitor cells. Its function is mediated via the G-CSF receptor, which was recently found to be expressed also in the central nervous system. In addition, G-CSF provided neuroprotection in models of neuronal cell death. Here we used the retinal ganglion cell (RGC) axotomy model to compare effects of local and systemic application of neuroprotective molecules. 相似文献15.
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Marijke WA de Backer Carlos P Fitzsimons Maike AD Brans Mieneke CM Luijendijk Keith M Garner Erno Vreugdenhil Roger AH Adan 《BMC neuroscience》2010,11(1):81
Background
This study compared the transduction efficiencies of an adeno-associated viral (AAV) vector, which was pseudotyped with an AAV1 capsid and encoded the green fluorescent protein (GFP), with a lentiviral (LV) vector, which was pseudotyped with a VSV-G envelop and encoded the discosoma red fluorescent protein (dsRed), to investigate which viral vector transduced the lateral hypothalamus or the amygdala more efficiently. The LV-dsRed and AAV1-GFP vector were mixed and injected into the lateral hypothalamus or into the amygdala of adult rats. The titers that were injected were 1 × 108 or 1 × 109 genomic copies of AAV1-GFP and 1 × 105 transducing units of LV-dsRed. 相似文献19.
We present a method to generate static, spherically symmetric, solutions of Einstein gravity in \(d+2\) dimensions minimally coupled to a real scalar field with a self-interacting potential. The solutions can be fully parametrised by a single function, whose behaviour encodes all the information about the local and global behaviour of the spacetime. We give several explicit applications of our solution-generating method that describe black holes, naked singularities and solitonic configurations.
相似文献20.
Mariano Cadoni Edgardo Franzin Matteo Tuveri 《The European Physical Journal C - Particles and Fields》2017,77(12):900
We define and compute the (analog) shear viscosity to entropy density ratio \(\tilde{\eta }/s\) for the QFTs dual to spherical AdS black holes both in Einstein and Gauss–Bonnet gravity in five spacetime dimensions. Although in this case, owing to the lack of translational symmetry of the background, \(\tilde{\eta }\) does not have the usual hydrodynamic meaning, it can be still interpreted as the rate of entropy production due to a strain. At large and small temperatures it is found that \(\tilde{\eta }/s\) is a monotonic increasing function of the temperature. In particular, at large temperatures it approaches a constant value, whereas at small temperatures, when the black hole has a regular, stable extremal limit, \(\tilde{\eta }/s\) goes to zero with scaling law behavior. Whenever the phase diagram of the black hole has a Van der Waals-like behavior, i.e. it is characterized by the presence of two stable states (small and large black holes), connected by a meta-stable region (intermediate black holes), the system evolution must occur through the meta-stable region- and temperature-dependent hysteresis of \(\tilde{\eta }/s\) is generated by non-equilibrium thermodynamics. 相似文献