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51.
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Francesca Maggioni Elisabetta Allevi Marida Bertocchi 《Journal of Optimization Theory and Applications》2014,163(1):200-229
Multistage stochastic programs, which involve sequences of decisions over time, are usually hard to solve in realistically sized problems. Providing bounds for optimal solution may help in evaluating whether it is worth the additional computations for the stochastic program vs. simplified approaches. In this paper we generalize measures from the two-stage case, based on different levels of available information, to the multistage stochastic programming problems. A set of theorems providing chains of inequalities among the new quantities are proved. Numerical results on a case study related to a simple transportation problem illustrate the described relationships. 相似文献
53.
Francesca Di Gaudio Sergio Indelicato Roberto Monastero Grazia Ida Altieri Francesca Fayer Ornella Palesano Manuela Fontana Angelo B. Cefalù Massimiliano Greco David Bongiorno Serena Indelicato Angela Aronica Davide Noto Maurizio R. Averna 《Analytical and bioanalytical chemistry》2016,408(9):2215-2226
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Andrea Temperini Lucio Minuti Tommaso Morini Ornelio Rosati Francesca Piazzolla 《Tetrahedron letters》2017,58(43):4051-4053
Functionalized primary, secondary and tertiary alcohols are efficiently acetylated by isopropenyl acetate and catalytic p-TsOH. 相似文献
55.
The synthesis of the methyl esters of optically pure trans and cis 4-guanidinocyclohexylglycine as rigid analogues of D-arginine methyl ester are described. 相似文献
56.
Mario Jug Francesca Maestrelli Paola Mura 《Journal of inclusion phenomena and macrocyclic chemistry》2012,74(1-4):87-97
β-Cyclodextrin (βCD) and its soluble polymeric derivative (EPIβCD) were used to improve the effectiveness of chitosan-based bucco-adhesive film formulations containing bupivacaine hydrochloride and triclosan as poorly-soluble model drugs. The film formulations were characterized in terms of swelling, mucoadhesion and in vitro drug release, while possible interactions between the components were investigated by DSC and FTIR analyses. For both drugs EPIβCD showed a higher solubilizing efficiency than βCD; however cyclodextrin effectiveness in improving the release rate from film formulations was influenced by their different interactions with chitosan. Free βCD acted as a channelling agent, favouring the film swelling, while EPIβCD due to interaction with chitosan caused an opposite effect. βCD was the optimal partner for bupivacaine-loaded films in terms of film swelling, mucoadhesion and drug release. Contrariwise, EPIβCD was the best partner for triclosan-loaded films, allowing the highest drug release rate increase, due to its higher solubilizing ability with respect to βCD. Addition of the suitable cyclodextrin enabled formulation of buccal films with suitable drug release properties. 相似文献
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Francesca Guerriero Filomena Olivito 《Journal of Mathematical Modelling and Algorithms》2014,13(3):247-282
In this paper, we consider the application of revenue management techniques in the context of the car rental industry. In particular, the paper presents a dynamic programming formulation for the problem of assigning cars of several categories to different segments of customers, with rental requests arising dynamically and randomly with time. Customers make a rental request for a given type of car, for a given number of days at a given pickup time. The rental firm can satisfy the demand for a given product with either the product requested or with a car of at most one category superior to that initially required, in this case an “upgrade” can take place. The one-way rental scenario, which allows the possibility of the rental starting and ending at different locations, is also addressed. In the framework considered, the logistic operator has to decide whether to accept or reject a rental request. Since the proposed dynamic programming formulations are impractical due to the curse of dimensionality, linear programming approximations are used to derive revenue management decision policies for the operator. Indeed, primal and dual acceptance policies are developed (i.e. booking limits, bid prices) and their effectiveness is assessed on the basis of an extensive computational phase. 相似文献
59.
This review reports on the latest developments in the field of magnetic nanocomposites, with a special focus on the potentials introduced by the incorporation of magnetic nanoparticles into polymer and supramolecular matrices. The general notions and the state of the art of nanocomposite materials are summarized and the results reported in the literature over the last decade on magnetically responsive films, capsules and gels are reviewed. The most promising concepts that have inspired the design of magneto-responsive nanocomposites are illustrated through remarkable examples where the integration of magnetic nanoparticles into organic architectures has successfully taken to the development of responsive multifunctional materials. 相似文献
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