Frequency effects in profile analysis and detecting complex spectral changes

Seven experiments on the detectability of intensity changes in complex multitonal acoustic spectra are reported. Two general questions organize the experimental efforts. The first question is how the detectability of a change in a flat (equal energy) spectrum depends on the frequency region where a single intensive change is made. The answer is that frequency region plays a relatively minor role. Frequency changes in the midregion of the spectrum are the easiest to hear, but thresholds increase by only about 5 dB over the range from 200 to 5000 Hz. For all frequencies, the psychometric function is of the form d' = k(delta p), where k is a constant and delta p is the change in pressure. The second question is how can we predict the detectability of complex changes over the entire frequency range from the detectability of change at each separate region. Thresholds for detecting a change from a flat spectrum to a spectrum whose amplitude varies in sinusoidal ("rippled") fashion over logarithmic frequency are measured at different frequencies of ripple. The thresholds are found to be independent of ripple frequency and are 7 dB higher than predicted on the basis of an optimum combination rule.     

Family communication about genetic risk: the little that is known

Although family communication is important in clinical genetics only a small number of studies have specifically explored the passing on of genetic knowledge to family members. In addition, many of these present exploratory or tentative findings based upon small sample sizes, or data collected only a short time after testing. Nevertheless, if health professionals are to develop effective strategies to help patients' deal with communication issues, we need to know more about what actually happens in families. The aim of this commentary is to identify factors which appear to influence whether patients share information about genetic risk with relatives who are unaware of that risk, with whom they share it and how they go about it. The paper draws upon evidence and thinking from the disciplines of psychology (including family therapy), sociology, medicine and genetic counselling. It is presented under the following headings: disease factors, individual factors, family factors and sociocultural factors. It concludes by highlighting a number of key issues which are relevant for health professionals.     

Sub‐glass‐transition temperature interface formation between an immiscible glass rubber pair

We used neutron reflectivity to measure the interfacial width in the immiscible system polystyrene/poly(n‐butyl methacrylate) (PS/PnBMA). Measurements were made on the same samples at temperatures ranging from below the glass‐transition temperature (T_g) of PS to slightly above. We observed significant broadening of the interface at temperatures below the T_g of PS, indicating chain mobility below the bulk T_g value. The interfacial width exhibited a plateau at a value of 20 Å in the temperature range of 365 K < T < 377 K. A control experiment involving hydrogenated and deuterated PS films (hPS/dPS) showed no such broadening over the same temperature region. The results are consistent with a reduction of the T_g of PS in the interfacial region of ～20 K. © 2001 John Wiley & Sons, Inc. J Polym Sci Part B: Polym Phys 39: 2664–2670, 2001     

Facile syntheses of quater-, penta-, and sexipyrroles

alpha,alpha-Linked oligopyrroles are attractive precursors for both expanded porphyrin and conducting polymer chemistry. We demonstrate facile methods for synthesizing quater-, penta-, and sexipyrroles from more readily available bi- and terpyrrole intermediates. These products demonstrate stability in their brightly colored oxidized forms, while reduction using borohydride reagents gives the corresponding all-pyrrole oligomers, which oxidize readily in air. The oxidized quater- and sexipyrroles were characterized by single-crystal X-ray diffraction analysis.     

Slow light in semiconductor quantum wells

We demonstrate slow light via population oscillation in semiconductor quantum-well structures for the first time. A group velocity as low as 9600 m/s is inferred from the experimentally measured dispersive characteristics. The transparency window exhibits a bandwidth as large as 2 GHz.     

Decision taking under pressure: Evidence on football manager dismissals in Argentina and their consequences

The paper focuses on dismissals of football managers and whether such decisions appear to contribute to organisational goals or else to be fruitless exercises in scapegoating. Its empirical setting is Argentina where incidence of sackings is more than one per season per club. It models 20 years of football match results and detects a tendency for a change of manager to be followed by deterioration in team performance, with adverse effects concentrated in results of matches played away. The evidence is consistent with decisions being driven by fan and media pressure rather than in realistic hope of improving the position of the club.