Olive Tree in Circular Economy as a Source of Secondary Metabolites Active for Human and Animal Health Beyond Oxidative Stress and Inflammation

Extra-virgin olive oil (EVOO) contains many bioactive compounds with multiple biological activities that make it one of the most important functional foods. Both the constituents of the lipid fraction and that of the unsaponifiable fraction show a clear action in reducing oxidative stress by acting on various body components, at concentrations established by the European Food Safety Authority’s claims. In addition to the main product obtained by the mechanical pressing of the fruit, i.e., the EVOO, the residual by-products of the process also contain significant amounts of antioxidant molecules, thus potentially making the Olea europea L. an excellent example of the circular economy. In fact, the olive mill wastewaters, the leaves, the pomace, and the pits discharged from the EVOO production process are partially recycled in the nutraceutical and cosmeceutical fields also because of their antioxidant effect. This work presents an overview of the biological activities of these by-products, as shown by in vitro and in vivo assays, and also from clinical trials, as well as their main formulations currently available on the market.     

Preparation and characterization of poly(urethane–urea) microcapsules containing limonene. Kinetic analysis

The synthesis of poly(urethane–urea) shells (PUU) using poly(ethylene glycols) of different molecular weights and methylene-bis(4-cyclohexylisocyanate) was performed for the microencapsulation of limonene, using a step-growth polymerization process. The obtained microcapsules were structurally characterized by dynamic light scattering, optical microscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, and thermogravimetric analysis. The results showed that the core–shell microcapsules had spherical shape, a mean diameter in between 10 and 20?µm, and characteristic urethane-urea bonds. Furthermore, the molecular weight of polyol influences the entrapment efficiency, which ranged from 38 to 55%. The release data were analyzed by applying the Korsmeyer–Peppas model.     

Computational Analysis of a Radiofrequency Knee Coil for Low-Field MRI Using FDTD

Magnetic resonance imaging (MRI) is essential for the diagnosis and treatment of musculoskeletal conditions. Low-field (<0.5T) imaging is a cost-effective alternative to more expensive high-field strength imaging due to the inexpensive setting, greater patient comfort and better safety profile. On the other hand, if compared with high-field body scanners, the low-field scanners produce poor-quality images with lower signal-to-noise ratio. Especially in low-field MR, receiver coil performance plays a significant role in image quality. Coil performance is generally evaluated using classical electromagnetic theory, but when the coil is loaded with a sample, an analytical solution is extremely difficult to derive, so that a trial-and-error approach is often followed. Numerical methods have been proposed in literature as good alternatives to predict MRI coil performance. In this study the performance of a knee coil for low-field (0.5 T) MR scanners is analyzed using workbench tests and numerical simulation with a software program based on the finite difference time domain method. Parameter performances measured using the classical workbench test are compared with those obtained using numerical simulations. Finally, the knee coil performance is validated with images acquired in a commercial low-field MR system.     

Classification of low energy sign-changing solutions of an almost critical problem

In this paper we make the analysis of the blow up of low energy sign-changing solutions of a semilinear elliptic problem involving nearly critical exponent. Our results allow to classify these solutions according to the concentration speeds of the positive and negative part and, in high dimensions, lead to complete classification of them. Additional qualitative results, such as symmetry or location of the concentration points are obtained when the domain is a ball.     

Uniqueness of Positive Solutions of Semilinear Elliptic Equations and Related Eigenvalue Problems

In this paper we survey some recent results about the uniqueness of the solution of some semilinear elliptic Dirichlet problems in bounded domains. The presentation aims to emphasize the role of the geometrical properties of the second eigenfunction of the linearized problem in the study of the above question. This motivates the analysis of the asymptotic behaviour of these eigenfunctions and of the relative eigenvalues when the nonlinear term is a power with exponent close to the critical Sobolev exponent. Research supported by MIUR, project “Variational Methods and Nonlinear Differential Equations”. Lecture held in the Seminario Matematico e Fisico on January 31, 2005 Received: June 2005     

Recovery of bioactive molecules from chestnut (Castanea sativa Mill.) by-products through extraction by different solvents

The underutilised forest and industrial biomass of Castanea sativa (Mill.) is generally discarded during post-harvest and food processing, with high impact on environmental quality. The searching on alternative sources of natural antioxidants from low-cost supplies, by methods involving environment-friendly techniques, has become a major goal of numerous researches in recent times. The aim of the present study was the set-up of a biomolecules extraction procedure from chestnut leaves, burs and shells and the assessing of their potential antioxidant activity. Boiling water was the best extraction solvent referring to polyphenols from chestnut shells and burs, whereas the most efficient for leaves resulted 60% ethanol at room temperature. Greatest polyphenol contents were 90.35, 60.01 and 17.68 mg gallic acid equivalents g^?1 in leaves, burs and shells, respectively. Moreover, flavonoids, tannins and antioxidant activity were assessed on the best extract obtained from each chestnut by-product.     

Bronze Age and Iron Age gold torcs and earrings from the Iberian Atlantic façade: a non‐invasive multi‐analytical approach to the characterisation of the alloys and the corrosion

A group of Bronze Age and Iron Age gold torcs and earrings from the Iberian Atlantic façade, several with tarnishing, are studied with different X‐ray‐based techniques, including portable devices for in situ analysis. The construction of the complex objects is discussed, and information on the evolution of the alloys is provided. By comparing the elemental composition of the analysed objects with published data for Bronze Age and Iron Age jewellery from the Portuguese area and with data obtained and published for Chalcolithic objects from the Iberian area, the changes in gold supplies could be discussed, and this has led to suggest changes in the chronological attribution of three torcs, on the reuse without melting of one pair of earrings and on the origin of the so‐called gold ingots. The analysis of tarnished areas of the torcs and the earrings showed the presence of distinct corrosion products due to atmospheric corrosion, which could be in part identified. Copyright © 2015 John Wiley & Sons, Ltd.     

Nonradial solutions of a nonhomogeneous semilinear elliptic problem with linear growth

In this paper we consider the problem