Dissolution and forming of cellulose with ionic liquids

The dissolution of cellulose in different ionic liquids will be described as a very recent subject for a direct dissolving process, which was used to prepare regenerated cellulose fibres. The preparation of the dopes was arranged starting from slurry of cellulose in the aqueous ionic liquid by removing the water at elevated temperature, vacuum and high shearing rates. As ionic liquids, the 1-N-Butyl-3-methylimidazolium chloride, the 1-Ethyl-3-methylimidazolium chloride, the 1-N-Butyl-2,3-dimethylimidazolium chloride, the 1-N-Butyl-3-methylimidazolium acetate and the 1-Ethyl-3-methylimidazolium acetate were investigated. The cellulose solutions in ionic liquids were characterised by means of light microscopy, cone-plate rheometry and particle analysis. In addition these results were compared with cellulose solutions in N-methyl-morpholine-N-oxide monohydrate. Finally the cellulose dopes were shaped by a dry-wet spinning process to manufacture cellulose fibres. The properties of the resulted fibre had been determined and will be discussed.     

Stable solutions of some ill-posed problems

Stable solutions of equations of the first kind and equations of the second kind at a characteristic value are given. Iterative processes for solutions are constructed. Extension of operators is used to turn an ill-posed problem into a well-posed one.     

Zur Theorie der ebenen,instationären Unterschallströmung um ein schwingendes Profil im Kanal

Summary The mixed boundary value problem for the determination of the velocity potential of an unsteady perturbation flow past an oscillating thin profile in an inviscid compressible gas at subsonic speeds is treated. After the separation of the wave-like terms in the Fourier expansions of the reduced potential, satisfying the Helmholtz wave equation, the boundary value problem for the remaining potential is transformed into a functional equation of the generalized Wiener-Hopf type by means of the Laplace transform. The familiar Wiener-Hopf technique leads to a linear system of infinitely many unknowns which can be solved by iteration for not too small profile lengths. Finally, two analytic expressions for the reduced potential in terms of different kernel functions and formulae for the lift and moment acting on the profile are written down.

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Diese Arbeit enthält einen Teil der von der Mathematisch-Naturwissenschaftlichen Fakultät der Universität des Saarlandes am 30. Oktober 1963 angenommenen Habilitationsschrift des Verfassers.     

Solvent Effects on the NMR Chemical Shifts of Imidazolium-Based Ionic Liquids and Cellulose Therein

The interactions of ionic liquids (IL) with solvents usually used in liquid-state nuclear magnetic resonance (NMR) spectroscopy are studied. The ¹H- and ¹³C-NMR chemical shift values of 1-n-butyl-3-methyl (BM)- and 1-ethyl-3-methyl (EM)-substituted imidazolium (IM) -chlorides (Cl) and -acetates (Ac) are determined before and after diluting with deuterated solvents (DMSO-d₆, D₂O, CD₃OD, and CDCl₃). The dilution offers structural modifications of the IL due to the solvents capacity to ionization. For further investigation of highly viscous cellulose dopes made of imidazolium-based IL, solid-state NMR spectroscopy enables the reproducibility of liquid-state NMR data of pure IL. The correlation of liquid- and solid-state NMR is shown on EMIM-Ac and cellulose/EMIM-Ac dope (10 wt %).     

Technological Opportunities for the Implementation of Anti-Microbial Activities into Dry-Wet Shaped Cellulose Fibres

Metal cations are valuable antimicrobial additives for controlling of bacteria growth on textile fibres. By means of multiple actions they are able to suppress the undesirable microbe action also during wound healing. Dry-wet shaping technology offers numerous opportunities for implementation of antimicrobial activities into textile structures (fibres, yarn, fabrics). The degree of load, insertion step as well as type of additive (Ag, Cu, Zn) presents a broad field of physical modification of dry-wet spun cellulose fibres. The investigation of antimicrobial activities of manufactured fibres and yarns exhibit bactericide or bacteriostatic effects against typical pathogenic germs. Ag contents higher than 30 ppm in fibres and 0.06 per cent in yarns as well as Cu contents higher than 100 ppm in fibres and about 0.5 per cent in yarns are fairly effective for a permanent antimicrobial effect. Fabrics based on the developed fibres and yarns could already been successfully commercialised by innovative small and medium sized enterprises (SME).     

Homogenous Carboxymethylation of Cellulose in the New Alkaline Solvent LiOH/Urea Aqueous Solution

In this work, the carboxymethylation of cellulose in a new alkaline cellulose solvent, LiOH/urea aqueous solution, was investigated. Carboxymethyl cellulose (CMC) samples were characterized with FT-IR, NMR, HPLC, and viscosity measurements. Water-soluble CMC with DS = 0.36∼0.65 was prepared, from both Avicel cellulose and cotton linters in the LiOH/urea system. The total DS of CMC could be controlled by varying the molar ratio of reagents and the reaction temperature. The results from structure analysis by HPLC after complete depolymerization showed that the mole fractions of the different carboxymethylated repeating units as well as those of unmodified glucose follow a simple statistic pattern. A distribution of the carboxymethyl groups of the AGU was determined to be in the order O-6 > O-2 > O-3 position at the level.     

Nonparametric Berkson regression under normal measurement error and bounded design

Regression data often suffer from the so-called Berkson measurement error which contaminates the design variables. Conventional nonparametric approaches to this errors-in-variables problem usually require rather strong conditions on the support of the design density and that of the contaminated regression function, which seem unrealistic in many cases. In the current note, we introduce a novel nonparametric regression estimator, which is able to identify the regression function on the whole real line under normal Berkson error although the location of the design variables is restricted to some bounded interval. The asymptotic properties of this estimator are investigated and some numerical simulations are provided.     

Two characterisations of the minimal triangulations of permutation graphs

A minimal triangulation of a graph is a chordal supergraph with an inclusion-minimal edge set. Minimal triangulations are obtained from adding edges only to minimal separators, completing minimal separators into cliques. Permutation graphs are the comparability graphs whose complements are also comparability graphs. Permutation graphs can be characterised as the intersection graphs of specially arranged line segments in the plane, which is called a permutation diagram. The minimal triangulations of permutation graphs are known to be interval graphs, and they can be obtained from permutation diagrams by applying a geometric operation, that corresponds to the completion of separators into cliques. We precisely specify this geometric completion process to obtain minimal triangulations, and we completely characterise those interval graphs that are minimal triangulations of permutation graphs.     

Sensitive detection of hydroxymethylcytosine levels in normal and neoplastic cells and tissues

A new sensitive analytical method using capillary electrophoresis with laser induced fluorescence (CE‐LIF) was applied for the simultaneous detection of DNA methylation and hydroxymethylation levels in human cancers of different origin. DNA hydroxymethylation, measured as 5‐hydroxymethylcytosine (5hmC) levels, was decreased in gliomas with mutation in the isocitrate dehydrogenase 1 (IDH1) gene when compared to IDH1‐wildtype gliomas. Independent from IDH1 mutation, 5hmC levels were decreased in lung carcinomas when compared to normal lung tissue. Reduced DNA hydroxymethylation was also observed upon dedifferentiation in cultured murine embryonic fibroblasts. Our data show that reduced DNA hydroxymethylation is related to cellular dedifferentiation and can be detected in various types of cancers, independent from the IDH1 mutation status. Quantitative determination of altered 5hmC levels may therefore have potential as a biomarker linked to cellular differentiation and tumorigenesis.