General Synthesis and Physicochemical Characterisation of a Series of Peptide‐Mimic Lysine‐Based Amino‐Functionalised Lipids

A series of novel malonic acid diamides (second generation) with two long hydrophobic alkyl chains and an alkaline polar head group was synthesised and characterised as a new class of amino‐functionalised lipids. These peptide‐mimic lipids are suitable for polynucleotide transfer. The lipids bear a novel backbone consisting of a lysine unit and a malonic acid unit. Six different head‐group structures, which vary in size and number of amino groups that can be protonated, were attached to the backbone structure. Furthermore, different alkyl chains were used to build the lipophilic part (namely tetradecyl, hexadecyl, and oleyl). Phase transitions of the new compounds in aqueous dispersions at pH 10 were analysed and discussed in terms of head group and alkyl chain variations. The shape and size of the formed aggregates of selected lipid dispersions were investigated by dynamic light scattering and transmission electron microscopy.     

New Process Simulation Procedure for High-Rate Plasma Jet Machining

Surface figuring using chemically reactive plasma jet machining (PJM) is a promising non-conventional technology for deterministic ultra-precision machining of optical components. Based on chemical reactions between plasma generated radicals and the surface atoms this technology is capable to fabricate complex shaped free form surfaces. Since the material removal rate during PJM depends strongly on the surface temperature which itself is influenced by the jet heat flux to the surface, the arising nonlinear effects on the etch result have to be regarded. Conventionally applied dwell time calculation algorithms do not consider those effects leading to significant machining errors in some cases. In order to improve the machining procedure with respect to deterministic material removal yielding predictable results a process simulation model has been developed. This model considers spatio-temporal variations of surface temperature and temperature dependent material removal and is able to predict the final workpiece topography after machining.     

L2Roe: a low dissipation version of Roe's approximate Riemann solver for low Mach numbers

A modification of the Roe scheme called L²Roe for low dissipation low Mach Roe is presented. It reduces the dissipation of kinetic energy at the highest resolved wave numbers in a low Mach number test case of decaying isotropic turbulence. This is achieved by scaling the jumps in all discrete velocity components within the numerical flux function. An asymptotic analysis is used to show the correct pressure scaling at low Mach numbers and to identify the reduced numerical dissipation in that regime. Furthermore, the analysis allows a comparison with two other schemes that employ different scaling of discrete velocity jumps, namely, LMRoe and a method of Thornber et al. To this end, we present for the first time an asymptotic analysis of the last method. Numerical tests on cases ranging from low Mach number (M_∞=0.001) to hypersonic (M_∞=5) viscous flows are used to illustrate the differences between the methods and to show the correct behavior of L²Roe. No conflict is observed between the reduced numerical dissipation and the accuracy or stability of the scheme in any of the investigated test cases. Copyright © 2015 John Wiley & Sons, Ltd.     

Double-knife EDGE problems with elastic/plastic type screens

A problem of diffraction of a wave by a pair of semi-infinite screens is considered. The screens are lined with two different wave bearing materials that can support surface waves. This type of problem arises in the propagation and, scattering of acoustic and electromagnetic waves by surface wave guides. To be specific, we shall couch our problem in terms of acoustics. These diffraction problems for two parallel wave bearing screens lead to boundary value problems which are governed by the Helmholtz equation, and some specific third kind boundary conditions. Such problems are shown to be well-posed for finite energy space solutions. Their representation is given by means of the canonical factorization of a non-rational matrix function.This work was supported by DFG grant KO 634/32-1     

Interaction of atomic hydrogen with the graphite single-crystal surface

The reaction of atomic hydrogen (or atomic deuterium) with highly orientated pyrolytic graphite surfaces has been studied by means of thermal desorption spectroscopy. In some cases atomic deuterium instead of atomic hydrogen, was used solely to assign the desorbed masses unambiguously to the different hydrocarbons. The desorption of D₂ and fourteen hydrocarbons was observed. D₂ desorbed at higher temperatures than the CH-(CD) compounds, the desorption spectra of the hydrocarbons contained two peaks. The dependence of the desorption spectra of several hydrocarbons on the heating rate, the atomic hydrogen exposure and the composition of the desorption products was investigated in detail. The kinetic parameters of the desorption process were determined for CH, C₂H₂, and CD₄. The spectra showed that there must be a first order desorption process for all the hydrocarbons, the values for the activation energy and the frequency factor were the same within experimental errors. The results were discussed by means of a simple model.     

Zu einigen mathematischen problemen in der theorie der transonischen strömung

The work deals with a definition of a weak solution of steady plane transonic flows past a thin profile, with the properties of the solution across a shock wave, and with a derivation of a conservative difference scheme suitable for numerical solution of the above mentioned problem by a finite difference method. The work presents several examples of numerical solution of transonic flows past a profile, through a plane cascade and some three-dimensional results. The numerical results presented are compared with experimental results or with numerical results by other authors.     

Modellierung und numerische Simulation der Thermoregulation von Früh- und Neugeborenen

Bei frühgeborenen S?uglingen spielt die Thermoregulation zur Aufrechterhaltung einer überlebenswichtigen K?rpertemperatur durch W?rmeproduktion, -abgabe bzw. -aufnahme eine entscheidende Rolle. Der Einsatz moderner Inkubatoren soll die k?rpereigenen Thermoregulatoren unterstützen, und es ist im Hinblick auf verschiedene medizinische Fragestellungen wünschenswert, diesen Prozess modellieren zu k?nnen. Wir stellen ein einfaches Modell auf der Basis von partiellen Differentialgleichungen vor und beschreiben detailliert die numerische Simulation mit Hilfe einer Finite-Volumen-Methode. Dazu wird ein zweidimensionales Modell eines Frühgeborenen trianguliert und das Modell diskretisiert. Zahlreiche numerische Resultate zeigen die Qualit?t unseres Modells.     

Modeling of stochastic forces in turbulent space plasmas

A model of a Langevin equation for electrons in turbulent, almost collisionfree magnetoactive plasmas is developed, which can form the starting point for particle simulations, especially in regions with reconnection of magnetic-field lines. The mean wave force is expressed by a friction force and a velocity derivative of the intensity of the stochastic force. The obtained expression for the Langevin force is consistent with the kinetic theory in a polarization approximation. The intensity of the stochastic force corresponds to the velocity diffusion tensor of the electrons, which is estimated for plasmas with ionacoustic turbulence using two different methods. One method is based on direct calculation of the space-time spectral density of the wave energy. The second method uses approximations of quasi-linear plasma theory. The estimates for the intensities of the stochastic forces found by the two methods differ by orders. A table of parameters of ion-acoustic waves, electron-wave collision frequencies, and intensities of stochastic-wave forces on electrons in solar flares, in the solar wind, as well as in different regions of the earth's magnetosphere is presented. Results are given for the entire ranges of available experimental data for the mean magnetic induction, mean plasma temperatures, and mean particle densities.Published from Izvestiya Vysshikh Uchebnykh Zavedenii, Radiofizika, Vol. 39, No. 1, pp. 93–107, January, 1996.