单轴晶体相位型光瞳滤波器

提出了一种基于单轴晶体制作的相位型光瞳滤波器,与普通的相位型光瞳滤波器相比较,单轴晶体相位型光瞳滤波器不仅制作简单,而且相位差有一定的可调节性。与液晶制作的相位型光瞳滤波器相比较,虽然单轴晶体相位型光瞳滤波器的可调节性不如液晶相位型光瞳滤波器,但是单轴晶体相位型光瞳滤波器成本低,而且也不会对光的衰减过大。单轴晶体相位型光瞳滤波器可以实现对焦斑分布的连续调节。通过理论分析和数值计算,论证了单轴晶体相位型光瞳滤波器的可行性,并且具体设计了两区型的单轴晶体相位型光瞳滤波器。     

硅紫外光伏探测器件响应度的研究

分析了硅紫外光伏探测器件的响应度与器件使用模式之间的关系．研究了包括网格结构在内的３种版图设计及所对应的响应度．结果表明，网格结构对改善紫外响应度的实际作用只是减小了串联电阻．细致讨论了光伏器件串联电阻的主要来源，给出了串联电阻对紫外响应度发生显著影响时所对应的估算数值．     

钇、钕与双希夫碱2-羟基-3-甲氧基苯甲醛缩联苯胺配合物的合成和光谱表征

在非水体系中首次合成了Ｙ（Ⅲ）、Ｎｄ（Ⅲ）与双希夫碱２－羟基－３－甲氧基苯甲醛缩联苯胺的固体配合物。用元素分析、摩尔电导、红外光谱、紫外光谱、核磁共振谱等方法研究其组成、一般性质和结构。     

对甲苯磺酰氟/双氧水/碱体系和烯烃环氧化反应的研究

研究了对甲苯磺酰氟和双氧水在碱性条件下原位生成对甲苯过氧磺酸和烯烃尤其是富电子烯烃的环氧化反应的情况. 该氧化体系能将位阻较小的富电子烯烃环氧化, 并以良好的得率给出环氧化产物; 对位阻较大的富电子烯烃, 只以中等得率生成了环氧化产物. 它也能将α,β-不饱和酮环氧化. 实验结果进一步拓展了磺酰氟试剂在有机合成化学中的应用.     

三区复振幅光瞳滤波器

利用光瞳滤波器来改变光在焦斑处的分布,是实现光学超分辨的有效途径。由于受到制作上的影响,现有的光瞳滤波器大都是纯相位型或者纯振幅型的。与纯相位或者纯振幅型光瞳滤波器相比较,复振幅型光瞳滤波器能够实现更好的滤波效果。不过由于制作上的困难,影响了复振幅的光瞳滤波器在实际中的应用。为此给出了一种相对容易实现的复振幅型光瞳滤波器,通过计算表明：在横向具有相同的第一零点比和斯特雷尔比下,该复振幅型光瞳滤波器的旁斑强度比优于纯相位型光瞳滤波器50％,并且有效地降低了纯相位型光瞳滤波器的轴向加宽。     

Hyperbranched rolling circle amplification as a rapid and sensitive method for species identification within the Cryptococcus species complex

The Cryptococcus species complex contains two closely related basidiomycetous yeasts: Cryptococcus neoformans and C. gattii, which cause cryptococcosis in humans and other animals. The species and varieties are characterized, by different clinical, epidemiological, biochemical and molecular features. The currently used identification methods are either time-consuming or not anymore commercially available. However, a rapid, sensitive and robust assay for the detection of these pathogens is vital for early diagnosis and appropriate treatment decisions. To overcome those limitations, four padlock probes targeting species-specific single nucleotide polymorphisms at the internal transcribed spacers (ITSs) of the RNA gene locus were developed and applied during isothermal hyperbranched rolling circle amplification (HRCA). The probes were tested against 99 samples, including 94 clinical cryptococcal cultures, three closely related Cryptococcus species, and two clinical specimens. The use of the padlock probes and the combination of probe signal amplification by HRCA provided a quick and sensitive assay for the accurate identification of C. neoformans var. grubii, C. neoformans var. neoformans and C. gattii. HRCA was also useful to detect hybrids, when they were heterozygous at the ITS locus. The HRCA results were in agreement with previous genotyping data based on PCR fingerprinting, amplified fragment length polymorphism and ITS sequencing.