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排序方式: 共有281条查询结果,搜索用时 15 毫秒
211.
Dumoulin F Lafont D Huynh TL Boullanger P Mackenzie G West JJ Goodby JW 《Chemistry (Weinheim an der Bergstrasse, Germany)》2007,13(19):5585-5600
Self-organisation and self-assembly are critical to the stability of synthetic and biological membranes. Of particular importance is consideration of the packing arrangements of the various molecular species. Both phospho- and glycolipids can pack in ways in which curvature can be introduced into self-organised or self-assembled systems. For instance, it is known that the degree of curvature can affect the structures of any condensed phases that are formed. In this article we report on a systematic study in which we have varied the shapes of glycolipids and examined the condensed phases that they form. In doing so, we have also unified the shape dependency of lyotropic liquid crystals with those of thermotropic liquid crystals. In order to undertake this systematic study a range of different pentaerythritol derivatives was synthesized, which covers combinations of one to three alkyl chains of different lengths (6,7,9,10,11,12,14,16 carbon atoms) and three to one galactosyl heads. Mono- and di-O-galactosyl derivatives were prepared directly by glycosylation of the corresponding alcohols using 2,3,4,6-tetra-O-benzoyl or acetyl-alpha-D-galactopyranosyl trichloroacetimidate or bromide as the donors; the tri-O-galactosyl derivatives were synthesized from O-alkyl-O-benzyl di-O-galactosyl pentaerythritol intermediates, followed by de-O-benzylation and glycosylation steps. All of the fully deprotected products were obtained by standard methods, and their self-organising and self-assembling properties examined. 相似文献
212.
Physical properties of silicone foams filled with carbon nanotubes and functionalized graphene sheets 总被引:2,自引:0,他引:2
Raquel Verdejo Cristina Saiz-Arroyo Fabienne Barroso-Bujans Miguel Angel Lopez-Manchado 《European Polymer Journal》2008,44(9):2790-2797
Free-rising silicone foams were made with loading fractions of up to 0.25 wt.-% functionalized graphene sheets (FGS) and up to 1.0 wt.-% carbon nanotubes (CNTs) using hydrogen as blowing agent. Scanning electron microscopy of the samples revealed an open cellular structure and a homogeneous dispersion of both types of nanofillers. The incorporation of nanofiller affected the foaming process and thus the final foam density and cellular structure. Transmission electron microscopy revealed the formation of a CNT network throughout the sample, while FGS presented an exfoliated and intercalated dispersion. The thermal stability of the samples was drastically affected by the presence of both nanofillers. Both nanofillers showed a positive effect on the compressive response of the foams. However, the nanocomposite foams were found to decrease the acoustic absorption with nanofiller content probably due to the variable foam structure and improved stiffness. 相似文献
213.
Ferrié L Boulard L Pradaux F Bouzbouz S Reymond S Capdevielle P Cossy J 《The Journal of organic chemistry》2008,73(5):1864-1880
A chemoselective synthesis of 1, the macrocyclic core of leucascandrolide A, has been achieved by utilizing highly enantioselective allylmetalations, an enantioselective Noyori reduction of a propargylic ketone, and olefin metatheses as the key steps. 相似文献
214.
Nonnenmacher J Massicot F Grellepois F Portella C 《The Journal of organic chemistry》2008,73(20):7990-7995
The diastereoselective nucleophilic trifluoromethylation of a range of ketoamides derived from L-tartaric acid has been studied. TMSCF3 in the presence of a catalytic amount of K2CO3 in DMF has been identified as the conditions leading to the highest diastereoselectivities. A sequential one-pot reaction trifluoromethylation-etherification of the trifluoromethylcarbinol has been developed. Only one further one-pot reaction, ketal hydrolysis-oxidative cleavage, led to the final alpha-trifluoromethylated alpha-alkoxyaldehydes. This procedure was applied to the preparation of a series of enantiopure aryl, heteroaryl, and alkyl alpha-trifluoromethyl-alpha-alkoxyaldehydes. 相似文献
215.
Pirovani CP Carvalho HA Machado RC Gomes DS Alvim FC Pomella AW Gramacho KP Cascardo JC Pereira GA Micheli F 《Electrophoresis》2008,29(11):2391-2401
Preparation of high-quality proteins from cacao vegetative organs is difficult due to very high endogenous levels of polysaccharides and polyphenols. In order to establish a routine procedure for the application of proteomic and biochemical analysis to cacao tissues, three new protocols were developed; one for apoplastic washing fluid (AWF) extraction, and two for protein extraction--under denaturing and nondenaturing conditions. The first described method allows a quick and easy collection of AWF--using infiltration-centrifugation procedure--that is representative of its composition in intact leaves according to the smaller symplastic contamination detected by the use of the hexose phosphate isomerase marker. Protein extraction under denaturing conditions for 2-DE was remarkably improved by the combination of chemically and physically modified processes including phenol, SDS dense buffer and sonication steps. With this protocol, high-quality proteins from cacao leaves and meristems were isolated, and for the first time well-resolved 1-DE and 2-DE protein patterns of cacao vegetative organs are shown. It also appears that sonication associated with polysaccharide precipitation using tert-butanol was a crucial step for the nondenaturing protein extraction and subsequent enzymatic activity detection. It is expected that the protocols described here could help to develop high-level proteomic and biochemical studies in cacao also being applicable to other recalcitrant plant tissues. 相似文献
216.
Murielle Rochelet Sébastien Solanas Laetitia Betelli Benoît Chantemesse Fabienne Vienney Alain Hartmann 《Analytica chimica acta》2015
An assay on the indirect amperometric quantification of the β-D-Glucuronidase (GLUase) activity was developed for the rapid and specific detection of Escherichia coli (E. coli) in complex environmental samples. The p-aminophenyl β-D-glucopyranoside (PAPG) was selected as an electrochemical substrate for GLUase measurement and the p-aminophenol (PAP) released during the enzymatic hydrolysis was monitored by cyclic voltammetry with disposable carbon screen-printed sensors. The intensity of the measured anodic peak current was proportional to the amount of GLUase, and therefore to the number of E. coli in the tested sample. Once the substrate concentration and pH values optimized, a GLUase detection limit of 10 ng mL−1 was achieved. Using a procedure involving a filtration step of the bacteria followed by their incubation with the substrate solution containing both the nonionic detergent Triton X-100 as permeabilization agent and the culture media Luria broth to monitor the growth, filtered bacterial cells ranging from 5 × 104 to 108 UFC/membrane were detected within 3 h. The amperometric assay was applied to the determination of fecal contamination in raw and treated wastewater samples and it was successfully compared with conventional bacterial plating methods and uidA gene quantitative PCR. Owing to its ability to perform measurements in turbid media, the GLUase amperometric method is a reliable tool for the rapid and decentralized quantification of viable but also nonculturable E. coli in complex environmental samples. 相似文献
217.
Fabienne Alary Romuald Poteau Jean-Louis Heully Jean-Claude Barthelat Jean-Pierre Daudey 《Theoretical chemistry accounts》2000,104(3-4):174-178
A new method for an increased numerical efficiency of ab initio calculations is proposed. It is based on the assumption that
in most cases chemical properties of functional groups in molecules are mainly controlled by a few electrons. This statement
allows one to distinguish between two classes of nuclei and electrons: active and inactive ones. The effective group potential
(EGP) method presupposes that the effect of inactive electrons in a functional chemical group can be described by a pseudopotential,
in the same way that core electrons are replaced by effective core potentials in atoms. It is shown that EGPs are able to
predict chemical and structural features of the active part of a molecule and at a fraction of the ordinary computational
cost. The preliminary results reported here concern the determination of EGPs for ammonia, the methyl radical and the cyclopendadienyl
ligand, which represent different types of bonding.
Received: 15 September 1999 / Accepted: 3 February 2000 / Published online: 2 May 2000 相似文献
218.
219.
Marina Rigling Fabienne Heger Maria Graule Zhibin Liu Chen Zhang Li Ni Yanyan Zhang 《Molecules (Basel, Switzerland)》2022,27(8)
Submerged fermentation of green tea with the basidiomycete Mycetinis scorodonius resulted in a pleasant chocolate-like and malty aroma, which could be a promising chocolate flavor alternative to current synthetic aroma mixtures in demand of consumer preferences towards healthy natural and ‘clean label’ ingredients. To understand the sensorial molecular base on the chocolate-like aroma formation, key aroma compounds of the fermented green tea were elucidated using a direct immersion stir bar sorptive extraction combined with gas chromatography–mass spectrometry–olfactometry (DI-SBSE-GC-MS-O) followed by semi-quantification with internal standard. Fifteen key aroma compounds were determined, the most important of which were dihydroactinidiolide (odor activity value OAV 345), isovaleraldehyde (OAV 79), and coumarin (OAV 24), which were also confirmed by a recombination study. Furthermore, effects of the fermentation parameters (medium volume, light protection, agitation rate, pH, temperature, and aeration) on the aroma profile were investigated in a lab-scale bioreactor at batch fermentation. Variation of the fermentation parameters resulted in similar sensory perception of the broth, where up-scaling in volume evoked longer growth cycles and aeration significantly boosted the concentrations yet added a green note to the overall flavor impression. All findings prove the robustness of the established fermentation process with M. scorodonius for natural chocolate-like flavor production. 相似文献
220.
Fabienne Faÿ Isabelle Linossier Gaëlle Legendre Karine Vallée-Réhel 《Macromolecular Symposia》2008,272(1):45-51
Summary: Environmental legislation compels marine paints companies to develop non toxic antifouling coatings respecting ecosystems. In this work, biodegradable polymers are used to conceive delivery systems with a lifetime of many months. For this purpose, chlorhexidine was encapsulated in poly(L-lactide) microspheres and incorporated in antifouling formulations. The characterization (encapsulation yield, surface morphology, particle size) and antibacterial activity (bacteriostatic and bactericidal effects) of microspheres were carried out by using scanning electronic (SEM) and confocal laser scanning microscopies (CLSM). The results indicate a good ability of loaded microspheres to be formulated even though an excellent activity against selected marine bacteria is conserved. This is a promising approach to develop biodegradable antifouling paints based on non toxic molecules and bioactive surfaces. 相似文献