Stability of oval cylindrical shells

Elastic buckling under aial compression of finite, oval cylindrical shells with clamped boundaries was investigated experimentally. The determination of the buckling strength was made on a series of oval shells made of Mylar A. The test results indicated that the discrepancy between theoretical and experimental initial buckling loads for the ovals is similar to that of the circular cylindrical shells. However, in contrast to the circular case, a collapse load significantly exceeding the initial buckling load is observed in the case of ovals with moderate-to-large eccentricity.     

Lipoide

Ohne Zusammenfassung     

Interactions of poly(amidoamine) dendrimers with Survanta lung surfactant: the importance of lipid domains

The interaction of generation 5 (G5) and 7 (G7) poly(amidoamine) (PAMAM) dendrimers with mica-supported Survanta bilayers is studied with atomic force microscopy (AFM). In these experiments, Survanta forms distinct gel and fluid domains with differing lipid composition. Nanoscale defects are induced by the PAMAM dendrimers. The positively charged dendrimers remove lipid from the fluid domains at a significantly greater rate than for the gel domains. Dendrimer accumulation on lipid edges and terraces preceding lipid removal has been directly imaged. Immediately following lipid removal, the mica surface is clean, indicating that lipid defects are not induced by dendrimers binding to the mica substrate and displacing the lipid.     

Mechanical Stimulation of Growth Plate Chondrocytes: Previous Approaches and Future Directions

Growth plate cartilage resides near the ends of long bones and is the primary driver of skeletal growth. During growth, both intrinsically and extrinsically generated mechanical stresses act on chondrocytes in the growth plate. Although the role of mechanical stresses in promoting tissue growth and homeostasis has been strongly demonstrated in articular cartilage of the major skeletal joints, effects of stresses on growth plate cartilage and bone growth are not well established. Here, we review the literature on mechanobiology in growth plate cartilage at macroscopic and microscopic scales, with particular emphasis on comparison of results obtained using different methodological approaches, as well as from whole animal and in vitro experiments. To answer these questions, macroscopic mechanical stimulators have been developed and applied to study mechanobiology of growth plate cartilage and chondrocytes. However, the previous approaches have tested a limited number of stress conditions, and the mechanobiology of a single chondrocyte has not been well studied due to limitations of the macroscopic mechanical stimulators. We explore how microfluidics devices can overcome these limitations and improve current understanding of growth plate chondrocyte mechanobiology. In particular, microfluidic devices can generate multiple stress conditions in a single platform and enable real-time monitoring of metabolism and cellular behavior using optical microscopy. Systematic characterization of the chondrocytes using microfluidics will enhance our understanding of how to use mechanical stresses to control the bone growth and the properties of tissue-engineered growth plate cartilage.

     

Kinetic collision detection between two simple polygons

We design a kinetic data structure for detecting collisions between two simple polygons in motion. In order to do so, we create a planar subdivision of the free space between the two polygons, called the external relative geodesic triangulation, which certifies their disjointness. We show how this subdivision can be maintained as a kinetic data structure when the polygons are moving, and analyze its performance in the kinetic setting.     

Laser induced fluorescence line narrowing in iodine

A complementary technique to Lamb dip absorption spectroscopy in gases is described which allows observation of homogeneous linewidths in fluorescence. Hyperline spectra of iodine excited by a single mode argon laser beam at 5145 Å are presented for the 43-13 and 43-11 bands at 5970 and 5830 Å respectively.     

A differential game model of the marketing-operations interface

In the development of their dynamic strategies, the marketing and operations functions within a firm have differing objectives, and conflict between the two functions is common. The strategic interdependence involving marketing and operations decisions is modeled as a noncooperative differential game. Demand is assumed to be a function of price and advertising goodwill, and marketing controls price and advertising to maximize its discounted stream of revenue net of advertising costs. Backlogging is allowed, and operations controls production to minimize its discounted stream of production and backlog costs. A feedback Nash equilibrium is derived for the game, which allows a solution of the system of differential equations for goodwill and backlog, and is analyzed to study the nature of the dynamic strategies for price, advertising, and production.     

Directed self-assembly of microcomponents enabled by laser-activated bubble latching

This article introduces a method for microscale assembly using laser-activated bubble latching. The technique combines the advantages of directed fluidic assembly and surface tension-driven latching to create arbitrarily complex and irregular structures with unique properties. The bubble latches, generated through the laser degradation of the tile material, are created on the fly, reversibly linking components at user-determined locations. Different phases of latching bubble growth are analyzed, and shear force calculations show that each bubble is able to support a tensile force of approximately 0.33 μN. We demonstrate that by exploiting the compressibility of bubbles, assembled objects can be made to switch between rigid and flexible states, facilitating component assembly and transport. Furthermore, we show reconfiguration capabilities through the use of bubble hinging. This novel hybrid approach to the assembly of microscale components offers significant user control while retaining a simplistic design environment.