全文获取类型
收费全文 | 511篇 |
免费 | 51篇 |
国内免费 | 14篇 |
专业分类
化学 | 468篇 |
力学 | 7篇 |
数学 | 36篇 |
物理学 | 65篇 |
出版年
2023年 | 5篇 |
2022年 | 16篇 |
2021年 | 16篇 |
2020年 | 31篇 |
2019年 | 34篇 |
2018年 | 41篇 |
2017年 | 30篇 |
2016年 | 45篇 |
2015年 | 31篇 |
2014年 | 50篇 |
2013年 | 77篇 |
2012年 | 32篇 |
2011年 | 28篇 |
2010年 | 20篇 |
2009年 | 17篇 |
2008年 | 21篇 |
2007年 | 20篇 |
2006年 | 12篇 |
2005年 | 7篇 |
2004年 | 7篇 |
2003年 | 12篇 |
2002年 | 13篇 |
2001年 | 3篇 |
2000年 | 1篇 |
1999年 | 1篇 |
1996年 | 1篇 |
1994年 | 1篇 |
1993年 | 1篇 |
1991年 | 1篇 |
1987年 | 1篇 |
1985年 | 1篇 |
排序方式: 共有576条查询结果,搜索用时 31 毫秒
111.
Nouri Parouch Ahmad Koukabi Nadiya Abdous Elham 《Research on Chemical Intermediates》2020,46(7):3295-3310
Research on Chemical Intermediates - In the present study, a magnetically separable potent solid acid nanocatalyst with a facile preparation technique was fabricated via incorporation of fibroin as... 相似文献
112.
Diabetes mellitus, which is the result of autoimmune destruction of the insulin-producing β cells, occurs by loss of insulin-secreting capacity. The insufficient source of insulin-producing cells (IPCs) is the major obstacle for using transplantation as diabetes treatment method. The present study suggests a method to form islet-like clusters of IPCs derived from mouse embryonic stem cells (mESCs). This protocol consists of several steps. Before starting this protocol, embryoid bodies (EBs) should be cultured in suspension in conditioned medium of isolated mouse pancreatic islet in combination with activing A to be induced. Then differentiated mESCs were replaced with dishes supplemented with basic fibroblast growth factor (bFGF). Next, bFGF was withdrawn, and cyclopamine and noggin were added. Then the cells were treated with B27, nicotinamide, and islet-conditioned medium for maturation. mESCs, as the control group, were cultured without any treatment. An enhanced expression of pancreatic-specific genes was detected by qRT-PCR and immunofluorescence in the differentiated mESCs. The differentiated mESCsco express other markers of pancreatic islet cells as well as insulin. This method exhibited higher insulin generation and further improvement in IPCs protocol that may result in an unlimited source of ES cells suitable for transplantation. The results indicated that conditioned medium, just as critical components of the stem cell niche associated with other factors, had high potential to differentiate mESCs into IPCs. 相似文献
113.
Elham Sattarzadeh Mostafa M. Amini Saeed Kakaei Alireza Khanchi 《Journal of Radioanalytical and Nuclear Chemistry》2018,317(3):1333-1339
In this study, magnetic multimodal nanoparticles with potential applications in magnetic- and nuclear-medicine imaging, magnetic resonance imaging, hyperthermia, and theranostic (therapeutic and diagnostic), applications were prepared by coating iron oxide nanoparticles with silica (core–shell), functionalizing with aminopropyltriethoxy silane and coupling with diethylenetriamine pentaacetic acid ligand (DTPA). Radiolabeling of core–shell–DTPA particles with 68Ga radiometal was carried out through chelation of 68Ga(III) ions by DTPA and was used for positron emission tomography. The biodistribution of the 68Ga-radiolabeled magnetic nanoparticles compared to free 68Ga(III) was checked in normal Balb/c mice up to 2 h. 相似文献
114.
Nour F. Attia Elham M. Hegazi A. A. Abdelmageed 《Journal of Thermal Analysis and Calorimetry》2018,132(3):1567-1578
Facile and smart method for the modification of inorganic fibers has been developed. The polyaniline was synthesized on basalt fiber surface presenting an organic polymer shell to the inorganic fibers. The modified basalt fibers were dispersed in rubber-producing well-dispersed rubber composites. Various mass loadings of modified basalt fibers were dispersed and optimized. The effect of radiation on the properties of developed rubber composites was investigated by exposure to different gamma radiation doses. The flammability, thermal and mechanical properties were studied. The flammability of developed composites was improved achieving 62 and 16% reduction in the peak heat release rate compared to blank rubber and unmodified basalt fiber-based rubber composite, respectively. This is in addition to significant reduction in emission of CO and CO2 gases by 65 and 58%, respectively. Also, the tensile strength property was enhanced by 38 and 53% compared to blank and unmodified basalt composite, respectively. The role of polyaniline layer on inorganic fiber surface and their effect on the properties of the produced composites was studied. The organic polymer shell achieved good compatibility and interfacial adhesion of basalt fibers with rubber matrix and radiation protection effect for the developed composites. 相似文献
115.
Designs, Codes and Cryptography - With the emergence of quantum communication, it is of folkloric belief that the security of classical cryptographic protocols is automatically broken if the... 相似文献
116.
Mir Ali?FarajzadehEmail author Mortaza?Ebrahimi Ali?Ranji Elham?Feyz Vali?Bejani Ramin?Maleki 《Mikrochimica acta》2005,150(2):173-177
This study describes the sample preparation and two chromatographic techniques for determination of Tinuvin 622 in polyethylene. The first part of the two methods consisting of dissolving the polyethylene in boiling xylene is followed by addition of a methanolic solution of potassium hydroxide. The polymeric light stabilizer, Tinuvin 622, is thereby saponified to 4-hydroxy-2,2,6,6-tetramethyl-1-piperidineethanol (diol). Addition of the methanolic solution of the saponification reagent simultaneously precipitates the polyethylene matrix. Then the diol is quantified using either gas chromatography (GC) or high performance liquid chromatography (HPLC). For GC, a Macherey Nagel Optima-17 capillary column (30m×0.25mm ID, film thickness 0.25µm) is used. Nitrogen is used as carrier gas and make-up gas. The detection system is a flame ionization detector. For HPLC, an octadecyl silane (ODS) column (30cm×4mm, particle size 5µm) and a mobile phase methanol: water mixture (3:97, v/v) are used. Detection of analyte is carried out at 215nm. Both methods can be used to determine Tinuvin 622 in polyethylene in the concentration range of 0.02–1%, which represents the usual application concentration. 相似文献
117.
The binding of a homologous series of n-alkyltrimethyl ammonium bromides with Jack bean urease (JBU) have been studied previously. It has been suggested that both electrostatic and hydrophobic interactions are involved in the formation of surfactant-protein complexes, but there is not any quantities analyzing method for resolution of their contributions in the process. In the present study, at first, the intrinsic Gibbs free energy of binding, ΔGb,ν, has been calculated for these systems and the trend of variation for both binding sets have been interpreted on basis of cooperativity and hydrophobicity of surfactants. Subsequently, a novel approach has been introduced for estimation of electrostatic and hydrophobic interactions in ΔGb,ν, by considering of this fact that ΔGb,ν is the summation of electrostatic, ΔGb,ν(ele), and hydrophobic, ΔGb,ν(hyd), parts and considering this fact that just ΔGb,ν(hyd) is a function of hydrocarbon tail length of surfactant (Cn). The results represents the higher positive rule of electrostatic interactions in binding affinity of first set and inhibiting rule of this interaction in the second binding set. The predominate driving force in the second binding set is entropy statistical effect, which arises from numerous number of binding sites in this set. A binding mechanism on basis of structural changes in JBU due to its interaction with cationic surfactants has also been proposed. 相似文献
118.
A variety of aromatic compounds are nitrated to parent nitro aromatic compounds under solvent-free conditions using 65% nitric acid in the presence of P2O5 supported on silica gel is described. This methodology is useful for nitration of activated and deactivated aromatic rings. 相似文献
119.
A novel one-pot, three-component condensation reaction of an aldehyde, 2-aminobenzothiazole and 2-naphthol or 6-hydroxyquinoline in water to give 2′-aminobenzothiazolomethyl naphthols or 5-(2′-aminobenzothiazolomethyl)-6-hydroxyquinolines in high yields at 90 °C without using any catalyst, is described. 相似文献
120.
Ahmad Shaabani Abbas Rahmati Masoumeh Sharifi Jafar Mogimi Rad Behnaz Aghaaliakbari Elham Farhangi Donald G. Lee 《Monatshefte für Chemie / Chemical Monthly》2007,138(7):649-651
Summary. The oxidation of arenes and sulfides by potassium permanganate was accomplished in good yields under solvent free and heterogeneous
conditions when manganese(II) sulfate is used as a solid support. After extraction of the organic products, the inorganic
products can be reoxidized to permanganate. This result is important because it provides an approach to oxidation reactions
that is, in theory, infinitely sustainable. 相似文献