排序方式: 共有59条查询结果,搜索用时 461 毫秒
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Matteo Andrea Lucherelli Yue Yu Giacomo Reina Gonzalo Abelln Eijiro Miyako Alberto Bianco 《Angewandte Chemie (International ed. in English)》2020,59(33):14034-14039
The synthesis of a drug delivery platform based on graphene was achieved through a step‐by‐step strategy of selective amine deprotection and functionalization. The multifunctional graphene platform, functionalized with indocyanine green, folic acid, and doxorubicin showed an enhanced anticancer activity. The remarkable targeting capacity for cancer cells in combination with the synergistic effect of drug release and photothermal properties prove the great advantage of a combined chemo‐ and phototherapy based on graphene against cancer, opening the doors to future therapeutic applications of this type of material. 相似文献
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Dr. Eijiro Miyako Dr. Julie Russier Dr. Matteo Mauro Dr. Cristina Cebrian Prof. Hiromu Yawo Dr. Cécilia Ménard‐Moyon Dr. James A. Hutchison Dr. Masako Yudasaka Prof. Sumio Iijima Prof. Luisa De Cola Dr. Alberto Bianco 《Angewandte Chemie (International ed. in English)》2014,53(48):13121-13125
A single organism comprises diverse types of cells. To acquire a detailed understanding of the biological functions of each cell, comprehensive control and analysis of homeostatic processes at the single‐cell level are required. In this study, we develop a new type of light‐driven nanomodulator comprising dye‐functionalized carbon nanohorns (CNHs) that generate heat and reactive oxygen species under biologically transparent near‐infrared (NIR) laser irradiation. By exploiting the physicochemical properties of the nanohorns, cellular calcium ion flux and membrane currents were successfully controlled at the single‐cell level. In addition, the nanomodulator allows a remote bioexcitation of tissues during NIR laser exposure making this system a powerful tool for single‐cell analyses and innovative cell therapies. 相似文献
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FAISAL Jamil-Qureshi 楼建玲 叶沿林 曹中鑫 江栋兴 郑涛 华辉 李智焕 李湘庆 葛愉成 庞丹阳 李奇特 肖军 吕林辉 乔锐 游海波 陈瑞九 卢飞 Sakurai H Otsu H Nishimura M Sakaguchi S Baba H Togano Y Yoneda K 李琛 王硕 王赫 李阔昂 Nakamura T Nakayama Y Kondo Y Deguchi S Satou Y Tshoo K H 《中国物理快报》2010,27(9):65-68
Differential cross sections for the elastic scattering of halo nucleus 6He on proton target were measured at 82.3 MeV/u. The experimental results axe well reproduced by optical model calculations using global potential KD02 with a reduction of the depth of real volume part by a factor of 0.7. A systematic analysis shows that this behavior might be related to the weakly bound property of unstable nuclei. 相似文献
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Z. Elekes Zs. Dombrádi A. Saito N. Aoi H. Baba K. Demichi Zs. Fülöp J. Gibelin T. Gomi H. Hasegawa N. Imai M. Ishihara H. Iwasaki S. Kanno S. Kawai T. Kishida T. Kubo K. Kurita Y. Matsuyama S. Michimasa T. Minemura T. Motobayashi M. Notani T. K. Ohnishi H. J. Ong S. Ota A. Ozawa H. K. Sakai H. Sakurai S. Shimoura E. Takeshita S. Takeuchi M. Tamaki Y. Togano K. Yamada Y. Yanagisawa K. Yoneda 《The European physical journal. Special topics》2007,150(1):99-102
This paper reports on the 1H(28Ne,28Ne) and 1H(28Ne,27Ne)
reactions studied at intermediate energy using a liquid hydrogen target. From
the cross section populating the first 2+ excited state of 28Ne, and using the previously
determined B(E2) value, the neutron quadrupole transition matrix element has been
calculated to be Mn=13.8 ±3.7 fm2.
In the neutron knock-out reaction, two low-lying excited states were populated in 27Ne.
Only one of them can be interpreted by the sd shell model while the additional state
may intrude from the fp shell. These experimental observations
are consistent with the presence of fp shell configurations at low excitation energy
in 27,28Ne nuclei caused by a vanishing N=20 shell gap at Z=10. 相似文献
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Eijiro Miyako Hideya Nagata Ken Hirano Yoji Makita Takahiro Hirotsu 《Chemical physics letters》2008,456(4-6):220-222
We have found that oxidized single-wall carbon nanohorns (SWNHox) can exhibit a near-infrared (NIR) laser-triggered accelerated release of encapsulated fullerenes (C60) from within their inner nanospaces. After the NIR laser irradiation of an aqueous SWNHox encapsulating C60 solution/toluene biphasic system, C60 molecules are enriched in the toluene phase. NIR laser-driven SWNHs encapsulating substrates could initiate the development of a new range of drug-delivery systems. 相似文献
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In Vivo Remote Control of Reactions in Caenorhabditis elegans by Using Supramolecular Nanohybrids of Carbon Nanotubes and Liposomes 下载免费PDF全文
Dr. Eijiro Miyako Dr. Svetlana A. Chechetka Dr. Motomichi Doi Dr. Eiji Yuba Prof. Kenji Kono 《Angewandte Chemie (International ed. in English)》2015,54(34):9903-9906
A supramolecular nanohybrid based on carbon nanotubes and liposomes that is highly biocompatible and capable of permeation through cells is described. The nanohybrid can be loaded with a variety of functional molecules and is structurally controlled by near‐infrared laser irradiation for the release of molecules from the nanohybrids in a targeted manner via microscopy. We implemented the controlled release of molecules from the nanohybrids and demonstrated remote regulation of the photoinduced nanohybrid functions. As a proof of principle, nanohybrids loaded with amiloride were successfully used in the spatiotemporally targeted blocking of amiloride‐sensitive mechanosensory neurons in living Caenorhabditis elegans. Our prototype could inspire new designs for biomimetic parasitism and symbiosis, and biologically active nanorobots for the higher‐level manipulation of organisms. 相似文献
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T YokoyaA Chainani T KissK Hirata Y TakanoK Togano H KitoH Ihara S Shin 《Journal of Physics and Chemistry of Solids》2002,63(12):2141-2144
We study the superconducting electronic structures of Nb3Al and MgB2 using high-resolution spectroscopy. The obtained spectrum of Nb3Al measured below Tc shows clear opening of the superconducting gap with a sharp pile up in the density of states and a shift of the leading edge. In addition, the spectrum shows a peak-dip-hump line shape expected from the strong-coupling theory. On the other hand, for MgB2, the superconducting-state spectrum measured at 5.4 K shows a coherent peak with a shoulder structure, in sharp contrast to that expected from a single isotropic gap. The superconducting spectral shape of MgB2 can be explained in terms of a multicomponent gap. 相似文献
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Elekes Z Dombrádi Z Aoi N Bishop S Fülöp Z Gibelin J Gomi T Hashimoto Y Imai N Iwasa N Iwasaki H Kalinka G Kondo Y Korsheninnikov AA Kurita K Kurokawa M Matsui N Motobayashi T Nakamura T Nakao T Nikolskii EY Ohnishi TK Okumura T Ota S Perera A Saito A Sakurai H Satou Y Sohler D Sumikama T Suzuki D Suzuki M Takeda H Takeuchi S Togano Y Yanagisawa Y 《Physical review letters》2007,98(10):102502
Neutron single particle energies have been measured in 23O using the 22O(d,p)23O*-->22O+n process. The energies of the resonant states have been deduced to be 4.00(2) MeV and 5.30(4) MeV. The first excited state can be assigned to the nu d3/2 single particle state from a comparison with shell model calculations. The measured 4.0 MeV energy difference between the nu s1/2 and nu d3/2 states gives the size of the N=16 shell gap which is in agreement with the recent USD05 ("universal" sd from 2005) shell model calculation, and is large enough to explain the unbound nature of the oxygen isotopes heavier than A=24. The resonance detected at 5.3 MeV can be assigned to a state out of the sd shell model space. Its energy corresponds to a approximately 1.3 MeV sized N=20 shell gap, therefore, the N=20 shell closure disappears at Z=8 in agreement with Monte Carlo shell model calculations using SDPF-M interaction. 相似文献