Sequential spectrophotometric determination of methanol and iron in vinegar by a flow injection-pervaporation method

An easily automatable sequential flow-injection-pervaporation method is proposed for the photometric determination of methanol and iron in vinegar. The method is based on separation of the methanol from the sample matrix by pervaporation followed by its oxidation to formaldehyde with permanganate, decolouration of the latter with S(2)O(5)(2-), and subsequent reaction of formaldehyde with p-rosaniline to yield a violet reaction product with maximum absorption at 567 nm. Iron is determined by an existing method based on reaction with thiocyanate in acidic medium and monitoring at 508 nm. After optimisation by either the univariate or multivariate approaches, as required, the linear range was established for methanol (4-1000 mg L(-1)) and iron (0.18-20 mg L(-1)). The proposed method was then compared with reference methods for methanol and iron in terms of repeatability (2.452 mg L(-1) and 0.245 mg L(-1), respectively), reproducibility (4.435 mg L(-1) and 0.356 mg L(-1), respectively), detection limit (LOD=82 and 0.234 mg L(-1), respectively), and traceability. The throughput was nine samples per hour.     

The computation of orthogonal rational functions and their interpolating properties

We shall consider nested spacesl _n ,n = 0, 1, 21... of rational functions withn prescribed poles outside the unit disk of the complex plane. We study orthogonal basis functions of these spaces for a general positive measure on the unit circle. In the special case where all poles are placed at infinity,l _n = _n , the polynomials of degree at mostn. Thus the present paper is a study of orthogonal rational functions, which generalize the orthogonal Szegö polynomials. In this paper we shall concentrate on the functions of the second kind which are natural generalizations of the corresponding polynomials.The work of the first author is partially supported by a research grant from the Belgian National Fund for Scientific Research     

Totally real imbeddings and the universal covering spaces of domains of holomorphy: Some examples

We begin with a review of the known examples of compact totally realn-dimensional submanifolds of _n . We then construct some new families of examples, including some which are simply connected. We conclude by using these examples to construct bounded domains of holomorphy in _n whose universal covering spaces are not biholomorphically equivalent to domains in _n .Herrn Prof. Dr. Karl Stein gewidmetResearch supported in part by Grant MCS 8301142 from the National Science FoundationResearch supported in part by Grant MCS 8219229 from the National Science Foundation     

Exploring azide-enolate cycloaddition in the synthesis of novel Rufinamide analogs

The exploration of azide-enolate cycloaddition in the synthesis of novel Rufinamide analogs is reported for the first time. A very simple procedure involving the use of β-ketonitriles as dipolarophiles afforded 5-aril/heteroayl Rufinamide derivatives in two steps.     

Synthesis,characterization and magnetic properties of mixed-valence iron complexes with 2-pyridyl oximes

Abstract

Two new mixed-valence iron complexes with 2-pyridyl oximes, [Fe(mpko)₃Fe(H₂O)₂(NO₃)](NO₃)·2H₂O (1) (mpko^? = methyl(2-pyridyl)ketone oximate) and [{Fe(dpko)₃}₂Fe](ClO₄)·4H₂O (2) (dpko^? = bis(2-pyridyl)ketone oximate), have been prepared by reaction of Fe^III with mpkoH in methanol (1) and Fe^II with dpkoH in methanol/water (2). Dinuclear Fe^II(low-spin)Fe^III(high-spin) and trinuclear Fe^II(low-spin)Fe^III(high-spin)Fe^II(low-spin) cations are present in the crystal structure of 1 and 2, respectively. Intermolecular hydrogen bonds in 1 lead to weak antiferromagnetic interactions between pairs of neighboring Fe^III centers, which allows observation of single-ion zero-field splitting effects.     

An Enzyme Immunoassay for Determining Immunoreactive Trypsinogen (IRT) in Dried Blood Spots on Filter Paper Using an Ultra-Microanalytical System

Cystic fibrosis (CF) is a severe autosomal recessive disorder. It is caused by mutations in the CF transmembrane conductance regulator gene. Early diagnosis of CF can be carried out by determining high immunoreactive trypsinogen (IRT) blood values in newborns. A simple sandwich-type ultramicroELISA assay (UMELISA®) has been developed for the measurement of IRT in dried blood spots on filter paper. Strips coated with a high affinity monoclonal antibody directed against IRT are used as solid phase, to ensure the specificity of the assay. The assay is carried out within 20 h. The useful rank of the curve is 0–500 ng/mL, and the lowest detectable concentration is 4.8 ng/mL. Intra- and inter-assay coefficients of variation were lower than 10%. The recovery mean value was 100.3 ± 11.2%. Cross-reactivity with proteins structurally related to IRT (α2-macroglobulin, α1-antitrypsin, and human chymotrypsin) was lower than the detection limit of the assay. Four thousand four hundred six newborn samples from the Cuban Newborn Screening Program were analyzed, and the mean IRT concentration was 12.8 ng/mL. Higher IRT values were obtained when samples were eluted overnight. Regression analysis showed a good correlation with the commercially available AutoDELFIA® Neonatal IRT kit (n?=?3948, r =?0.885, ??=?0.976, p?<?0.01). The analytical performance characteristics of our UMELISA® TIR Neonatal suggest that it can be used for the neonatal screening of CF.     

Instrumental neutron activation analysis of peloids from main Cuban spas

Journal of Radioanalytical and Nuclear Chemistry - Peloids from some Cuban spas (San Diego, Elguea, Santa Lucía, Cajío and Colony) have been studied using Instrumental Neutron Activation...     

A first glance into the nutritional properties of the sea cucumber Parastichopus regalis from the Mediterranean Sea (SE Spain)

This work reports for the first time the nutritional profile, including proximate chemical composition, amino acids, fatty acids and minerals of Parastichopus regalis from the Mediterranean Sea (SE Spain). The studied species had a high moisture content, moderate protein and low lipid levels. The most abundant amino acids were glutamic acid, arginine and tyrosine. Polyunsaturated fatty acids, especially arachidonic acid, dominated the fatty acid profile. Iron, sodium, calcium and zinc were the most abundant mine rals. In general, P. regalis has a balanced nutritional quality suitable for human consumption.