Indication of reactor ν(e) disappearance in the Double Chooz experiment

The Double Chooz experiment presents an indication of reactor electron antineutrino disappearance consistent with neutrino oscillations. An observed-to-predicted ratio of events of 0.944±0.016(stat)±0.040(syst) was obtained in 101 days of running at the Chooz nuclear power plant in France, with two 4.25 GW(th) reactors. The results were obtained from a single 10 m(3) fiducial volume detector located 1050 m from the two reactor cores. The reactor antineutrino flux prediction used the Bugey4 flux measurement after correction for differences in core composition. The deficit can be interpreted as an indication of a nonzero value of the still unmeasured neutrino mixing parameter sin(2)2θ(13). Analyzing both the rate of the prompt positrons and their energy spectrum, we find sin(2)2θ(13)=0.086±0.041(stat)±0.030(syst), or, at 90% C.L., 0.017相似文献   

On the nuclear curvature energy

The curvature energy coefficient of the nuclear mass formulaa _c is first calculated for the model case of a Fermi gas bounded by an external Woods-Saxon potential. The semiclassical theory of Wigner and Kirkwood is used anda _c is found to be close to zero. It is, however, shown that this low value is due to the lack of selfconsistency of the potential. When available, the results of the model compare very well with quantal values and the extrapolation to the spherical cavity (billiard) checks with the value fora _c known from the Balian-Bloch theory. Second, the selfconsistent case is generalised to finite range forces. No indication is found that this modifies the fact that all theoretical values for a _c are larger than about 7 MeV which is an order of magnitude above the empirical value.     

The Ruderman-Kittel-Kasuya-Yosida interaction in amorphous La80Au20 alloys with dilute Gd impurities

From magnetization measurements on some amorphous dilute La_80?xGd_xAu₂₀ alloys with x ? 1 we have shown that the magnetic behavior follows the scaling laws of a spin-glass system, characteristic of the 1/r³ dependence of the pairwise interaction. We have also determined the strength of the Ruderman-Kittel-Kasuya-Yosida interaction V(r) = (V₀cos 2k_Fr)/r³, to be V₀ = 0.20 × 10^?37 ergcm³. The corresponding value of the s-f exchange integral is |J_sf| = 0.14 eV, which is compared with values determined from other experiments.     

The Potential of 2-Substituted Quinolines as Antileishmanial Drug Candidates

There is a need for new, cost-effective drugs to treat leishmaniasis. A strategy based on traditional medicine practiced in Bolivia led to the discovery of the 2-substituted quinoline series as a source of molecules with antileishmanial activity and low toxicity. This review documents the development of the series from the first isolated natural compounds through several hundred synthetized molecules to an optimized compound exhibiting an in vitro IC₅₀ value of 0.2 µM against Leishmania donovani, and a selectivity index value of 187, together with in vivo activity on the L. donovani/hamster model. Attempts to establish structure–activity relationships are described, as well as studies that have attempted to determine the mechanism of action. For the latter, it appears that molecules of this series act on multiple targets, possibly including the immune system, which could explain the observed lack of drug resistance after in vitro drug pressure. We also show how nanotechnology strategies could valorize these drugs through adapted formulations and how a mechanistic targeting approach could generate new compounds with increased activity.     

Structure of optimal transport networks subject to a global constraint

The structure of pipe networks minimizing the total energy dissipation rate is studied analytically. Among all the possible pipe networks that can be built with a given total pipe volume (or pipe lateral surface area), the network which minimizes the dissipation rate is shown to be loopless. Furthermore, such an optimal network is shown to contain at most N-2 nodes in addition to the N sources plus sinks that it connects. These results are valid whether the possible locations for the additional nodes are chosen freely or from a set of nodes (such as points of a grid). Applications of these results to various physical situations and to the efficient computation of optimal pipe networks are also discussed.     

Rechenautomat 704 IBM

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