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131.
Dr. Mamdouh S. Masoud T. M. Salem M. Elessawi 《Monatshefte für Chemie / Chemical Monthly》1978,109(1):221-227
The reactions of the bidentate dinitrosoresorcinol (DNR) with copper, cobalt, nickel, iron and zinc salts were investigated. This ligand was found to react with these metal salts in aqueous media where hydrogen ion was confirmed to be liberated except in case of iron. The solid complexes were prepared in alcoholic media. Chemical analyses, magnetic and spectral data were compatible to determine the structure of these complexes and their mode of chelation.
Mit 2 Abbildungen 相似文献
Mit 2 Abbildungen 相似文献
132.
Prof. Dr. Heinz Falk Alfred Leodolter Georg Schade 《Monatshefte für Chemie / Chemical Monthly》1978,109(1):183-192
The electrochemical oxidation of arylmethylene-pyrrolinones, pyrromethenones and pyrromethenes as representative bile pigment partial structure models was investigated by means of a rotating disc platinum electrode using acetonitrile as the solvent. Two different oxidation reactions were found. The first reaction being a reversible one-electron oxidation with compounds of the arylmethylene-pyrrolinone series and pyrromethenones which are unsubstituted in position 5 of the pyrrole ring. A two step reaction (the first one reversible, the second irreversible) on the other hand was found to be typical for pyrromethenones bearing a methyl group in this position.Through protonation the first step is at a higher potential, whereas the second one is lowered and becomes reversible. The resulting oxidation pattern can be interpreted analogous to the oxidation of hydroquinones in aprotic solvents.The geometrical isomers of a pyrromethenone were oxidized at appr. the same potential, but there is a strong dependence of the potential of the first oxidation step on the substitution: a higher degree of alkylation favours oxidation by lowering the oxidation potential.
Mit 1 Abbildung 相似文献
Mit 1 Abbildung 相似文献
133.
Chen TF Yoder JD Hruby DE 《European journal of mass spectrometry (Chichester, England)》2004,10(4):501-508
Myristoylpeptides were synthesized in order to determine if a neutral loss of 210 Da, C14H26O (the mass of the myristoyl moiety), was universal and observable by both liquid chromatography electrospray ionization quadrupole ion trap (LC-ESI-QIT) and matrix-assisted laser desorption/ionization time-of-flight time-of-flight (MALDI-ToF/ToF) mass spectrometry. Myristoylation was successfully introduced on the N-terminus, internally on the amino group of lysine and arginine. Larger peptides and the arginine compounds needed elevated temperatures for myristoylation. To our knowledge, this is the first report of a chemically-synthesized myristoylated arginine in a peptide. Collision energy studies for the LC-ESI-QIT instrument showed that modified peptides and a loss of 210 Da could be detected under commonly used conditions (energy level between 30 and 42%) with picomole amounts of sample. The loss of myristoyl moiety is observed on the MALDI-Tof/Tof mass spectrometer as well. Due to the hydrophobic properties of the myristoyl moiety, it is not surprising that the modified peptides all formed at least dimers, and in some cases trimers. We were also able to distinguish a mixture of two mono-myristoylated peptides. MS3 data from the LC-ESI-QIT instrument on a di-myristoylated peptide indicates the loss of 210 Da at either the N-terminus or lysine. We were also able to analyze a mixture of modified and unmodified peptides on the MALDI-ToF/ToF instrument. The data presented in this paper demonstrates the constant neutral loss of the 210 Da, C14H26O, from both N-terminally and internally myristoylated peptides can be identified unambiguously using LC-ESI-QIT or MALDI-ToF/ToF mass spectrometers. This will be a useful tool in determining the myristoylation status of candidate proteins after enzyme digestion, and in elucidating the modification sites of internal myristoyl proteins. 相似文献
134.
Dr. W. Gottardi 《Monatshefte für Chemie / Chemical Monthly》1975,106(3):611-623
By reaction of primary carboxamides with “dibromoisocyanuric acid” (DBI) N-monobromoamides can be readily obtained as well as the N,N-dibromoamides described in an earlier paper1. Reactions, some of them new, and properties of these compounds are described and compared with those of the N,N-dibromoamides. Like other compounds bearing the NHBr group2, 3 the N-monobromocarboxamides disproportionate at room temperature according to: 2 RCONHBr ? ? RCONH2+RCONBr2. For CH3CONHBr the equilibrium constant was found to beK=0.02. In aqueous solution they behave as weak acids. The dissociation constants of eight compounds [R=?CH3, ?C2H5, ?CH2Cl, ?CHCl2, ?CCl3, ?CF3, ?C(CH3)3 and ?C6H5] were measured: they differ from those of the corresponding carboxylic acids by about three powers of ten. 相似文献
135.
Dipl.-Ing. Dr. O. Hinterhofer 《Monatshefte für Chemie / Chemical Monthly》1974,105(2):279-290
The selective chlorination of a m/p-xylene mixture, followed by distillation of the unreacted p-xylene, leaves a residue containing up to 90% of monochlorinated m-xylenes. m-Xylene is recovered from the latter by heterogeneous catalytic hydrogenolysis in the gas-phase. It was found that the hydrogenolysis on certain noble metal catalysts proceeds according to an ionic reaction mechanism at temperatures below a definite temperature range. At temperatures above this range hydrogenolysis follows a radical reaction mechanism. 相似文献
136.
Simultaneous determination of cefazolin in rat blood and brain by microdialysis and microbore liquid chromatography 总被引:3,自引:0,他引:3
A sensitive microbore liquid chromatographic method combined with the minimally invasive technique of microdialysis was devised for simultaneously and continuously monitoring the levels of unbound blood and brain cefazolin in rats. Microdialysis probes were inserted into the jugular vein and brain striatum for blood and brain sampling, respectively. Chromatographic conditions consisted of a mobile phase of methanol-acetonitrile-100 mM monosodium phosphoric acid (20:10:70, v/v, pH 4.5) pumped through a microbore reversed-phase column at a flow rate of 0.05 mL/min. The ultraviolet detection wavelength was set at 270 nm. An on-line design allowed direct and continuous analysis of protein-free samples in the dialysate. Microdialysis probes, being home-made, were screened for acceptable in vivo recovery. Chromatographic resolution and detection were validated for response linearity as well as intra-day and inter-day variabilities. This method was then applied to pharmacokinetic profiling of protein unbound cefazolin in both the blood and brain following intravenous administration (10 mg/kg, i.v., n = 6). Rapid appearance of cefazolin in the rat brain striatal dialysate following drug injection suggested good blood-brain barrier penetration. According to a non-compartmental pharmacokinetics model, the area under the concentration (AUC) vs time ratio of cefazolin in rat brain and blood was 6%. 相似文献
137.
A novel route for waste water treatment: photo-assisted Fenton degradation of dye pollutants accumulated in natural polyelectrolyte microshells 总被引:2,自引:0,他引:2
The efficient accumulation of dyes in constructed natural polyelectrolyte microshells under moderate conditions, combined with the photo-assisted Fenton reagent, opens a new route for the effective elimination of dye pollutants from waste water. 相似文献
138.
Isomeric structures and energies of three kinds of lithofluorosilylenoids, R2SiLiF (R = NH2, OH, F) were studied using theab initio molecular orbital theory. The calculations show that thermal stability of the three-membered ring structures of these three
kinds of silylenoids decreases in the order of substituents NH2 > OH > F because of the conjugation between NH2, OH or F and Si atom. The interaction of substituents R with Li atom makes R2SiLiF have a structure with two Li-A-Si-F (A = N, O, F) four-membered rings, which is the most stable of the isomers of each
of three kinds of silylenoids and whose stability decreases in the order of substituents F > OH > NH2. Inductive effect of substituents influences the thermal stability of the linear structure of silylenoids. 相似文献
139.
The introduction of a 5-trimethylsilyl group on the least hindered face of the diene thebaine was anticipated to favor attack by dienophiles from the alternate face, but only gave rise to a rearrangement product when treated with 3-butene-2-one at 110 °C. Reaction with the more reactive benzoquinone at lower temperature gave rise to a very slow reaction from the same face as the silyl group, indicating that a trimethylsilyl group does not sufficiently hinder this face to achieve reaction at the other face. 相似文献
140.
The stoichiometry and structure of acetophenone benzoylhydrazone and acetophenone salicoylhydrazone chelates with some divalent metal ions are studied by conductometric titration and visible and infra-red absorption spectrophotometry. The results are supported by analysis of the solid complexes. The infra-red study revealed that coordination occurs through C=O and C=N groups. The shift in the C=O and C=N bands is utilised for the determination of bond lengths. 相似文献