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971.
We have partially purified active delta and epsilon subunits of the E. coli membrane-bound Mg2+-ATPase (ECF1). Treating purified ECF1 with 50% pyridine precipitates the major subunits (alpha, beta, and gamma) of the enzyme, but the two minor subunits (delta and epsilon), which are present in relatively small amounts, remain in solution. The delta and epsilon subunits were then resolved from one another by anion exchange chromatography. The partially purified epsilon strongly inhibits the hydrolytic activity of ECF1. The epsilon fraction inhibits both the highly purified five-subunit ATPase and the enzyme deficient in the delta subunit. The latter result indicates that the delta subunit is not required for inhibition by epsilon. By contrast, two-subunit enzyme, consisting chiefly of the alpha and beta subunits, was insensitive to the ATPase inhibitor, suggesting that the gamma subunit may be required for inhibition by epsilon. The partially purified delta subunit restored the capacity of ATPase deficient in delta to recombine with ATPase-depleted membranes and to reconstitute ATP-dependent transhydrogenase. Previously we reported (Biochem, Biophys. Res. Commun. 62:764 [1975]) that a fraction containing both the delta and epsilon subunits of ECF1 restored the capacity of ATPase missing delta to recombine with depleted membranes and to function as a coupling factor in oxidative phosphorylation and for the energized transhydrogenase. These reconstitution experiments using isolated subunits provide rather substantial evidence that the delta subunit is essential for attaching the ATPase to the membrane and that the epsilon subunit has a regulatory function as an inhibitor of the ATPase activity of ECF1. 相似文献
972.
S. P. Tripathi G. K. Chaturvedi R. C. Sharma 《Monatshefte für Chemie / Chemical Monthly》1978,109(2):283-287
Stepwise mixed ligand complex formation has been cited for the formation of 111,Ln(III)—NTA—catechol ternary complexes potentiometrically [whereLn(III)=La(III), Pr(III) or Nd(III)]. The results of titration curves indicate the formation of 11,Ln(III)—NTA complexes in beginning and the addition of catechol, takes place later on in the higher buffer region. The relative stability of these ternary complexes in terms of metal ion has been reported as La(III)< 相似文献
973.
Prof. Dr. K. -H. Hellwege U. Johnsen Dipl.-Phys. W. Seufert 《Colloid and polymer science》1963,188(1):11-14
Zusammenfassung PÄT-Folien wurden in Luft, Stickstoff und Vakuum bei 20 °C mit 1 MeV-Elektronen bestrahlt. Untersucht wurden Löslichkeit und Viskosität von Proben, die unmittelbar nach der Bestrahlung gelöst wurden.In allen untersuchten Fällen trat bei hohen Bestrahlungsdosen ein unlöslicher, d. h. vernetzter Anteil auf, dessen Ausbildung jedoch durch in den Proben enthaltene Feuchtigkeit verzögert werden kann. Bei niedrigen Bestrahlungsdosen bewirkt Feuchtigkeit einen Abbau des Polymeren, wie durch Viskositätsmessungen gezeigt wird.Aus den Gel-Messungen wurde derp
0/q
0-Wert für Bestrahlung in Luft, Stickstoff und Vakuum zu 1,05 bestimmt.Die Änderung des Gel-Anteils bei Lagerung der Proben zwischen Bestrahlung und Lösung wird diskutiert.
Herrn Diplom-PhysikerH. Fischer sei an dieser Stelle für wertvolle Anregungen und Diskussionen besonders gedankt. 相似文献
Summary Polyethyleneterephthalate samples were irradiated in air, nitrogen and vacuum at 20 °C with 1 MeV electrons. The solubility of the samples and the viscosity of the solutions were studied immediately after irradiation. At high doses an insoluble crosslinked part was always observed. Crosslinking was delayed by moisture in the samples. At low irradiation doses moisture causes chain scission as shown by viscosity measurements. The ratiop 0/q 0 of degradation to crosslinking in the case of irradiation in air, nitrogen and vacuum was found by gel measurements to be 1.05. The insoluble gel-part changes with increasing storage time of the samples between irradiation and solution.
Herrn Diplom-PhysikerH. Fischer sei an dieser Stelle für wertvolle Anregungen und Diskussionen besonders gedankt. 相似文献
974.
Zusammenfassung Die Speicher- und VerlustmodulnG undG verdünnter Lösungen (2–4%) dreier Isobutylenpolymerisate mit den Molekulargewichten 0,63, 1,29 und 11×105 wurden in der Apparatur vonBirnboim undFerry über einen Frequenzbereich von 0,4–400 Hz und einen Temperaturbereich von –17,5 bis 25,0° bestimmt. Für die scharf fraktionierten Polymerisate von niederem Molekulargewicht ergab die Frequenzabhängigkeit der Moduln eine ausgezeichnete Übereinstimmung mit der Theorie vonZimm. Die aus den experimentell erhaltenen Kurven ermittelten Molekulargewichte und größten Relaxationszeiten waren von der erwarteten Größenordnung. Für das Polymerisat mit höherem Molekulargewicht entsprach die Frequenzabhängigkeit vonG undG –
s
jedoch der Theorie vonRouse. Der Einfluß der hydrodynamischen Wechselwirkung in der Bewegung der Knäuelsegmente, in welchem der Unterschied zwischen den beiden Theorien besteht, erscheint als von der Größe des Molekulargewichts abhängig.
Summary The storage and loss moduliG andG of dilute (2–4%) solutions of three polyisobutylenes of molecular weight 0.63, 1.29, and 11×105 were determined in the apparatus ofBirnboim andFerry over a frequency range of 0.4 to 400 cps, and a temperature range of –17.0 to 25.0°. The sharply fractionated polymers of low molecular weight showed a frequency dependence in excellent agreement with the theory ofZimm. The experimentally determined molecular weights and terminal relaxation times were of the expected order of magnitude. The frequency dependence of the polymer of highest molecular weight, however, conformed more closely to the theory ofRouse. The influence of the hydrodynamic interaction on the motion of the coil segments, which constitutes the difference in the two theories, appears to depend on the magnitude of the molecular weight.相似文献
975.
[reaction: see text] Protein farnesyltransferase (PFTase) catalyzes alkylation of cysteine residues by farnesyl diphosphate (FPP). The dissociation constants for the PFTase-peptide analogue complexes for the series of analogues fl-RTRC(X)VIA (X = H, methyl, dodecyl, farnesyl) were measured by fluorescence anisotropy. The results indicate that an ionizable sulfhydryl moiety is important for substrate binding and the farnesyl group in the product facilitates binding. 相似文献
976.
Thermomagnetic experiments are shown to be a useful and rapid technique for studying phase changes involving magnetic materials. Particular examples are chosen from Chromindur II (Fe28Cr10.5Co) alloys having different thermal histories. The Curie temperature of the single phase alloy is found to be ~650°C and the metastable spinodal decomposition boundary is at essentially the same temperature. The Cr-rich near equilibrium decomposition product is less magnetic and has a lower Tc, while the Cr-deficient product is more magnetic, with a Tc ? 720°C.Comparisons are made at different heating and cooling rates between temperatures measured using magnetic standards and those measured by a thermocouple in close proximity to the sample. 相似文献
977.
The condensation products of 5-amino-1,3-disubstituted-pyrazoles with aromatic aldehydes were identified as 2,4-dihydro-2,5-diphenyl-4-(phenylmethylene)-3H-pyrazol-5-imine derivatives Treatment of these products with mercaptoacetic acid gave new fluorine containing 1H-pyrazolo[3,4-e][1,4]thiazepin-7-ones. 相似文献
978.
G. Menchi
S. Paganelli
U. Matteoli A. Scrivanti C. Botteghi 《Journal of organometallic chemistry》1993,450(1-2):229-235The unsaturated compounds 1,2-dicarbethoxy-1,2,3,6-tetrahydropyridazine 1 and 1,2-dicarbethoxy-1,2,3,4-tetrahydropyridazine 2 have been hydroformylated and hydrocarbethoxylated in the presence of some well known cobalt, rhodium, palladium and platinum catalysts. The hydroformylation reaction can be tuned by a suitable choice of the catalyst precursor and reaction conditions, thus allowing the synthesis with high selectivity of one of the two possible isomeric aldehydes. The carbonylation reaction is less synthetically useful, since it shows low activity and unsatisfactory chemo- and regio-selectivity. However, the ester 1,2,4-tricarbethoxyhexahydropyridazine 10 can be prepared in good yield from olefin 1 by using the complex [PdCl2(PPh3)2] as the catalyst precursor. 相似文献
979.
980.
Michael C. Böhm 《Theoretical chemistry accounts》1983,62(4):351-372
The crystal orbital formalism in the tight-binding approximation is combined with a recently developed CNDO/INDO model for transition metal species of the 3d series in order to allow band structure calculations on the Hartree-Fock (HF) SCF level for one-dimensional (1D) chains with organometallic unit cells. The band structure approach based on the CNDO and INDO approximation can be used for any atom combination up to bromine under the inclusion of the 3d series. The matrix elements for the tight-binding Hamiltonian are derived for an improved CNDO and INDO framework. The total energy of the 1D chain is partitioned into one-center contributions and into two-center increments of the intracell and intercell type. Semiempirical band structure calculations on simple model systems are compared with available ab initio data of high quality. 相似文献