全文获取类型
收费全文 | 131篇 |
免费 | 6篇 |
国内免费 | 2篇 |
专业分类
化学 | 96篇 |
晶体学 | 1篇 |
数学 | 34篇 |
物理学 | 8篇 |
出版年
2023年 | 1篇 |
2022年 | 6篇 |
2021年 | 7篇 |
2020年 | 3篇 |
2019年 | 1篇 |
2018年 | 3篇 |
2017年 | 4篇 |
2016年 | 7篇 |
2015年 | 3篇 |
2014年 | 9篇 |
2013年 | 14篇 |
2012年 | 9篇 |
2011年 | 2篇 |
2010年 | 4篇 |
2009年 | 8篇 |
2008年 | 7篇 |
2007年 | 6篇 |
2006年 | 5篇 |
2005年 | 5篇 |
2004年 | 4篇 |
2003年 | 3篇 |
2002年 | 6篇 |
2001年 | 1篇 |
2000年 | 2篇 |
1997年 | 2篇 |
1996年 | 1篇 |
1995年 | 2篇 |
1990年 | 2篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1982年 | 2篇 |
1981年 | 1篇 |
1979年 | 2篇 |
1974年 | 1篇 |
排序方式: 共有139条查询结果,搜索用时 31 毫秒
81.
Dorina R ADUCANU 《数学年刊B辑(英文版)》2013,34(4):515-528
The author considers a new class SHm λμ(α) of normalized analytic functions defined by a diferential operator. Several basic properties and characteristics of the functions belonging to the class SHm λμ(α) are investigated. These include integral representations, coefcient bounds, the Fekete-Szego¨ problem, class-preserving operators and T δ-neighborhoods. 相似文献
82.
Pietro Belotti 《Journal of Global Optimization》2013,56(3):787-819
We describe a procedure to reduce variable bounds in mixed integer nonlinear programming (MINLP) as well as mixed integer linear programming (MILP) problems. The procedure works by combining pairs of inequalities of a linear programming (LP) relaxation of the problem. This bound reduction procedure extends the feasibility based bound reduction technique on linear functions, used in MINLP and MILP. However, it can also be seen as a special case of optimality based bound reduction, a method to infer variable bounds from an LP relaxation of the problem. For an LP relaxation with m constraints and n variables, there are O(m 2) pairs of constraints, and a naïve implementation of our bound reduction scheme has complexity O(n 3) for each pair. Therefore, its overall complexity O(m 2 n 3) can be prohibitive for relatively large problems. We have developed a more efficient procedure that has complexity O(m 2 n 2), and embedded it in two Open-Source solvers: one for MINLP and one for MILP. We provide computational results which substantiate the usefulness of this bound reduction technique for several instances. 相似文献
83.
84.
Ioana Dorina Vlaicu Rodica Olar Ctlin Maxim Mariana Carmen Chifiriuc Coralia Bleotu Nicolae Stnic Gina Vasile Sceeanu Constana Dulea Sperana Avram Mihaela Badea 《应用有机金属化学》2019,33(7)
This paper presents the synthesis, physico‐chemical and biological properties of four new coordination compounds with mixed ligands: acrylate ion (acr) and benzimidazole/benzimidazole derivatives with the general formula [Co(L) 2 (acr) 2 ]·nH 2 O [ (1) L: benzimidazole (HBzIm), n: 0.5; (2) L: 2‐methylbenzimidazole (2‐MeBzIm), n: 0.5; (3) L: 5‐methylbenzimidazole (5‐MeBzIm), n: 0; (4) L: 5,6‐dimethylbenzimidazole (5,6‐Me2BzIm), n: 0]. Their chemical formulae were achieved correlating the chemical analysis with mass spectrometry data, the ligands coordination modes were assigned by Fourier transform‐infrared measurements, and the trigonal bipyramidal geometry of cobalt ion in complexes was assigned by data correlation of UV–Vis‐NIR spectra and magnetic moments measurements. Single‐crystal X‐ray diffraction reveals a mononuclear structure with a pentacoordinated cobalt (II) ion, connected to two acrylato coordinated in different modes and two unidentate 5,6‐dimethylbenzimidazole ligands for compound (4) . The biological tests were performed against several microbial strains, the cytotoxicity was evaluated on HCT8 cellular lines and the cell cycle analysis was performed on HT29 cellular lines. Microbiological assays indicated that Co (II) complexes present a very good to good activity against Candida albicans 1760, Enterococcus faecium E5, Bacillus subtilis ATCC 6683 and Escherichia coli ATCC 25922. Predictive pharmacokinetic (ADME), toxicity and drug‐likeness profiles were evaluated for Co (II) complexes. Our results highlight that Co (II) complexes depicted in the present study are suitable to be used as efficient pharmacological agents. 相似文献
85.
The method of mortality forecasting proposed by Lee and Carter describes a time series of age‐specific log‐death rates as a sum of an independent of time age‐specific component and a bilinear term in which one of the component is a time‐varying factor reflecting general change in mortality and the second one is an age‐specific parameter. Such a rigid model structure implies that on average the mortality improvements for different age groups should be proportional, regardless of the calendar period: a single time factor drives the future death rates. This paper investigates the use of multivariate time series techniques for forecasting age‐specific death rates. This approach allows for relative speed of decline in the log death rates specific to the different ages. The dynamic factor analysis and the Johansen cointegration methodology are successfully applied to project mortality. The inclusion of several time factors allows the model to capture the imperfect correlations in death rates from 1 year to the next. The benchmark Lee–Carter model appears as a special case of these approaches. An empirical study is conducted with the help of the Johansen cointegration methodology. A vector‐error correction model is fitted to Belgian general population death rates. A comparison is performed with the forecast of life expectancies obtained from the classical Lee–Carter model. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
86.
We consider layer potentials associated with the Hodge-Laplacian acting on differential forms of arbitrary degree defined on Lipschitz subdomains of a Riemannian manifold. The main emphasis is on the interplay between the mapping properties of such layer potentials and the topology of the underlying domain.Partially supported by a UMC Research Board GrantPartially supported by NSF grant DMS-9870018 相似文献
87.
Dorina Trifonova‐Van Haeringen Jozsef Varga Gottfried W. Ehrenstein G. Julius Vancso 《Journal of Polymer Science.Polymer Physics》2000,38(5):672-681
The lamellar organization of melt‐crystallized β‐isotactic polypropylene was studied by atomic force microscopy (AFM) after permanganic etching. Hedritic objects grown at a high crystallization temperature (140–143 °C) were investigated. Essential features of the hedritic development were revealed by the characteristic projections exposed at the sample surface. A three‐dimensional view of the morphology was obtained by AFM. Hedritic growth proceeded mainly by branching around screw dislocations resulting in new lamellae that further developed. Successive lamellar layers often diverged. Deviation from the planar lamellar habit was observed, varying with the position within the hedrite. Twisting of the lamellae also was observed occasionally in the vicinity of the screw dislocations. © 2000 John Wiley & Sons, Inc. J Polym Sci B: Polym Phys 38: 672–681, 2000 相似文献
88.
Dorina Gabriella Dob Zsfia Nmeth Bence Sipos Martin Cseh Edina Pallagi Dniel Berkesi Gbor Kozma Zoltn Knya Ildik Cska 《Molecules (Basel, Switzerland)》2022,27(5)
This study aimed to produce thermosensitive liposomes (TSL) by applying the quality by design (QbD) concept. In this paper, our research group collected and studied the parameters that significantly impact the quality of the liposomal product. Thermosensitive liposomes are vesicles used as drug delivery systems that release the active pharmaceutical ingredient in a targeted way at ~40–42 °C, i.e., in local hyperthermia. This study aimed to manufacture thermosensitive liposomes with a diameter of approximately 100 nm. The first TSLs were made from DPPC (1,2-dipalmitoyl-sn-glycerol-3-phosphocholine) and DSPC (1,2-dioctadecanoyl-sn-glycero-3-phosphocholine) phospholipids. Studies showed that the application of different types and ratios of lipids influences the thermal properties of liposomes. In this research, we made thermosensitive liposomes using a PEGylated lipid besides the previously mentioned phospholipids with the thin-film hydration method. 相似文献
89.
Tainah Dorina Marforio Edoardo Jun Mattioli Francesco Zerbetto Matteo Calvaresi 《Molecules (Basel, Switzerland)》2022,27(6)
The persistency of COVID-19 in the world and the continuous rise of its variants demand new treatments to complement vaccines. Computational chemistry can assist in the identification of moieties able to lead to new drugs to fight the disease. Fullerenes and carbon nanomaterials can interact with proteins and are considered promising antiviral agents. Here, we propose the possibility to repurpose fullerenes to clog the active site of the SARS-CoV-2 protease, Mpro. Through the use of docking, molecular dynamics, and energy decomposition techniques, it is shown that C60 has a substantial binding energy to the main protease of the SARS-CoV-2 virus, Mpro, higher than masitinib, a known inhibitor of the protein. Furthermore, we suggest the use of C70 as an innovative scaffold for the inhibition of SARS-CoV-2 Mpro. At odds with masitinib, both C60 and C70 interact more strongly with SARS-CoV-2 Mpro when different protonation states of the catalytic dyad are considered. The binding of fullerenes to Mpro is due to shape complementarity, i.e., vdW interactions, and is aspecific. As such, it is not sensitive to mutations that can eliminate or invert the charges of the amino acids composing the binding pocket. Fullerenic cages should therefore be more effective against the SARS-CoV-2 virus than the available inhibitors such as masinitib, where the electrostatic term plays a crucial role in the binding. 相似文献
90.