高效液相色谱氮杂冠醚键合固定相的合成及性能研究

我们曾用γ－氯丙基键合硅胶（ＣＰＳ），在氢化钠（ＮａＨ）作用下合成了３－（氮杂－１８－冠－６）丙基键合固定相（ＢＣＰ）［１］．该固定相对碱基、核苷酸、硝基苯酚等有较好的分离选择性，但由于ＮａＨ对硅胶基质腐蚀作用较大，导致ＢＣＰ柱效及渗透性较低．本文采...     

CHARACTERIZATION OF AMPHIPHILIC AND MICROPHASE SEPARATED GRAFT COPOLYMERS Ⅱ SURFACE CHARACTERIZATION AND IN VITRO BLOOD-COMPATIBILITY ASSESSMENT OF POLYSTYRENE-GRAFT-ω-STEARYLPOLY (ETHYLENE OXIDE)*

This paper reported the research results concerning the surface characterization ofpolystyrene-graft-w-stearyl poly(ethylene oxide) (PS-g-SPEO) by means of XPS,contactangle measurement and TEM, and its in vitro blood compatibility assessment by measuringthe plasma recalcification time (RT) and partial thromboplastin time (PTT). The XPSresults demonstrated that the surface and bulk composition of the PS-g-SPEO graftcopolymers differ remarkably from each other,and that SPEO component was constantlyenriched at the copolymer/air interface. Contact angle studies indicated that the surfacewater wettability can be adjusted effectively by changing the composition of the copolymer.PS-g-SPEO graft copolymers can undergo microphase separation as clearly illustrated byTEM photographs. The relationship between the surface properties of PS-g-SPEO graftcopolymer and its blood compatibility was also discussed.     

K＋I~2→K^+＋I~2^-离子对生成反应态－态几率与 选态截面的量子散射理论研 究

本文用Miller的-矩阵变分法在Aten-Lanting-Los两态势能面上计算了K＋I~2→K^+＋I~2^-电离反应的态－态几率和选态反应截面,结果表明了低电离阈能、几率的振荡行为及振动增强效应;电离截面随碰撞能及I~2振动量子数的变化规律与实验预测相吻合;讨论了反应机理。     

SYNTHESIS OF POLY ( ETHER-URETHANE) CONTAINING PENDANT AMINO GROUP

This paper is concerned with the synthesis of poly (ether-urethane) with pendant amino groups. The copolyether produced by ring opening copolymerization of tetrahydrofuran and epibromohydrin was treated with sodium azide in dimethylformamide to form azido substituted copolyether. The poly (ether-urethane) made from it was subjected to reduction reaction to convert azido group to amino group. The stress-strain behavior and dynamic-mechanical properties of poly (ether-urethane) containing pendant amino groups were studied.     

Octa-membered Water Ring Chain Based on Sulfonic Group in Ni（Ⅱ） Complex with 2-[（E）-（2-Oxidophenyl）methyleneamino] Ethanesulfonato and 2,2＇-Bipyridinyl

The title compound, [Ni（tssb）（2,2-bipy）2].5（H2O） 1 （tssbH2 =2-[（E）-（2-oxido- phenyl）methyleneamino]ethanesulfonato, 2,2-bipy = 2,2＇-bipyridinyl）, belongs to orthorhombic, space group Pbcn with a = 20.3983（18）, b = 17.6929（15）, c = 17.0897（15） nm, V= 6167.8（9） nm^3, Mr= 688.38, Z = 8, De = 1.481 g.cm^-3, F（000） = 2880,μ = 0.758 mm-1 and S =1.099. Each NiIr atom is six-coordinated by one N and one O atoms from one tssb^2- anion and four N atoms from two 2,2-bipy ligands to give a distorted octahedral geometry. Noticeably, there exists a rare octa-mem- bered water ring which presents a 1D chain by sulfonic group.     

PHOTOSENSITIVITY OF Ce (Ⅳ) INITIATED METHYL ACRYLATE POLYMERIZATION

The influences of UV light irradiation (313 nm) and diffused daylight on the polymerization of methyl acrylate initiated by the ceric ammonium nitrate without any reducing agent have been studied both in aqueous nitric acid and in pure water. The rate of polymerization was found to be accelerated and the overall activation energy and the induction time were found to be decreased sharply by the UV light irradiation. Under UV light, the rate of polymerization is 8 times as high as the rate in dark. The rate of polymerization was found to attain a maximum with the increase of nitric acid concentration and the rate of polymerization became less sensitive to UV light in the presence of nitric acid whereas the induction period reduced outstandingly. Based on the experimental results, the mechanism is proposed.     

STUDIES ON CHARGE TRANSFER POLYMERIZATION——POLYMERIZATION OF ACRYLONITRILE INITIATED WITH PHENYL HYDRAZINE AND ITS DERIVATIVES

The photopolymerization of acrylonitrile (AN) initiated with phenyl hydrazine (PHZ) and its derivatives has been studied. The initiator exponent and monomer exponent were determined from the kinetic investigation to be 0.66th and 2.1th respectively and the overall activation energy was 33.4KJ/mol for the PHZ-AN system. Spectral analysis and other data indicate that a charge transfer complex between PHZ as a donor and AN as an aceeptor is formed. The initiation mechanism was proposed.     

富锌排铅咀嚼片安全性毒理学评价

对富锌排铅咀嚼片(RZLR)进行了急性毒性试验、Ames试验、骨髓微核试验、精子畸形试验和30 d喂养试验。结果表明,小鼠急性毒性LD50(BW)>21 500 mg/kg,属无毒级;Ames试验、小鼠骨髓微核试验、精子畸形试验和30 d喂养试验结果均为阴性;30 d喂养试验也未显示明显毒性。本研究证实RZLR是一种安全、无毒副作用的保健食品。     

The Photopolymerization Kinetics of Acryl amide Sensitized with Toluidine Blue-Alcoholamine Induced by He-Ne Laser

Toluidine blue(TB) is a good sensitizer for the polymerization of acrylnmide(AM) induced by He-Ne laser. With TB as a sensitizer and various alcoholamine as donors, the photoredox of TB and the polymerization kinetics of AM induced by He-Ne laser were investigated. It was found that either for the photoredox of TB or for the polymerization of AM, the activity of alcoholamine increases in the order of EOA相似文献   

辣根过氧化物酶对心肌线粒体过氧化损伤的保护作用

以黄嘌呤氧化酶／次黄嘌呤自由基诱生系统建立了稳定的离体心肌线粒体的损伤模型，并应用此模型研究辣根过氧化物酶对心肌线粒体自由基氧化损伤的保护作用，结果表明，辣根过氧化物酶能抑制心肌线粒体中氧自由基的形成，降低膜脂的过氧水平，保护了线粒体膜酶活性，有效地防止自由基对线粒体结构和功能的损伤。