全文获取类型
收费全文 | 713篇 |
免费 | 10篇 |
国内免费 | 1篇 |
专业分类
化学 | 386篇 |
晶体学 | 3篇 |
力学 | 48篇 |
数学 | 156篇 |
物理学 | 131篇 |
出版年
2023年 | 3篇 |
2022年 | 17篇 |
2021年 | 30篇 |
2020年 | 8篇 |
2019年 | 19篇 |
2018年 | 12篇 |
2017年 | 6篇 |
2016年 | 37篇 |
2015年 | 21篇 |
2014年 | 26篇 |
2013年 | 46篇 |
2012年 | 36篇 |
2011年 | 38篇 |
2010年 | 27篇 |
2009年 | 17篇 |
2008年 | 25篇 |
2007年 | 39篇 |
2006年 | 35篇 |
2005年 | 39篇 |
2004年 | 32篇 |
2003年 | 16篇 |
2002年 | 18篇 |
2001年 | 13篇 |
2000年 | 6篇 |
1999年 | 11篇 |
1998年 | 3篇 |
1997年 | 8篇 |
1996年 | 9篇 |
1995年 | 4篇 |
1994年 | 10篇 |
1993年 | 5篇 |
1992年 | 10篇 |
1991年 | 5篇 |
1990年 | 3篇 |
1989年 | 3篇 |
1988年 | 3篇 |
1987年 | 7篇 |
1986年 | 3篇 |
1985年 | 5篇 |
1984年 | 6篇 |
1983年 | 7篇 |
1982年 | 6篇 |
1981年 | 5篇 |
1980年 | 7篇 |
1977年 | 6篇 |
1975年 | 3篇 |
1968年 | 2篇 |
1928年 | 2篇 |
1915年 | 2篇 |
1905年 | 2篇 |
排序方式: 共有724条查询结果,搜索用时 15 毫秒
111.
Scaramozzino Domenico Lacidogna Giuseppe Piana Gianfranco Carpinteri Alberto 《Meccanica》2019,54(13):1927-1940
Meccanica - Protein mechanical vibrations play a pivotal role in biological activity. In particular, low-frequency (terahertz) modes are related to protein conformational changes, which represent... 相似文献
112.
Attanasi OA Favi G Filippone P Giorgi G Mantellini F Moscatelli G Spinelli D 《Organic letters》2008,10(10):1983-1986
The versatility of the Mukaiyama-Michael-type addition/heterocyclization of Danishefsky's diene with 1,2-diaza-1,3-butadienes was applied to the synthesis of both 4 H-1-aminopyrroles and 4,5 H-pyrazoles. Thus, the same reagents furnished different types of highly functionalized azaheterocycles essentially depending on their structure: as a matter of fact, R1 = COOR or CONR 2 differently affects the acidity of the proton at the adjacent carbon. An unexpected formation of 5 H-1-aminopyrroles from the reactions carried out in water was also observed. 相似文献
113.
114.
We study existence and possible uniqueness of special semihypergroups of type U on the right. In particular, we prove that there exists a unique proper semihypergroup of this kind having order 6, apart
of isomorphisms; the least order for a hypergroup of type U on the right to have a stable part which is not a subhypergroup is 9; and the minimal cardinality of a proper semihypergroup
of that kind whose heart and derived semihypergroup are proper and nontrivial is 12.
Contextually, we analyze properties of the kernel of homomorphisms g : H ↦ G, where H is a finite semihypergroup of type U on the right and G is a group. In this way, we obtain results that are immediately applicable both to the heart and to the derived of such semihypergroups.
相似文献
115.
Prof. Domenico C. M. Albanese Dr. Michele Penso 《European journal of organic chemistry》2023,26(19):e202300224
Phase Transfer Catalysis (PTC) is a powerful tool to perform reactions in a practical fashion, both in laboratory and industrial scale. Significant cost savings and major process improvements can be achieved in reactions performed under PTC conditions. In the last few years remarkable results in stereoselective reactions were achieved using chiral, non-racemic quaternary ammonium salts. Moreover, the use of bulky, chiral phosphate anions paired with achiral cations to generate lipophilic ion pairs allowed to design new avenues for the stereoselective construction of important building blocks. Hydrogen bond interactions were also shown to provide new pathways for asymmetric nucleophilic substitutions using insoluble reagents under PTC conditions. This Review will focus on recent advances in developing practical synthetic routes to construct molecules in a stereoselective fashion under PTC conditions. 相似文献
116.
Domenico Candeloro Anca Croitoru Alina Gavriluţ Anna Rita Sambucini 《Mediterranean Journal of Mathematics》2016,13(5):2551-2575
A comparison between a set-valued Gould type and simple Birkhoff integrals of bf(X)-valued multifunctions with respect to a non-negative set function is given. Relationships among them and Mc Shane multivalued integrability is given under suitable assumptions. 相似文献
117.
Alessandro Stroppa Paolo Barone Domenico Di Sante Mario Cuoco Silvia Picozzi Myung‐Hwan Whangbo 《International journal of quantum chemistry》2016,116(20):1442-1450
In developing physical theories, analogical reasoning has been found to be very powerful, as attested by a number of important historical examples. An analogy between two apparently different phenomena, once established, allows one to transfer information and bring new concepts from one phenomenon to the other. Here, we discuss an important analogy between two widely different physical problems, namely, the Jahn–Teller distortion in molecular physics and the Rashba spin splitting in condensed matter physics. By exploring their conceptual and mathematical features and by searching for the counterparts between them, we examine the orbital texture in Jahn–Teller systems, as the counterpart of the spin texture of the Rashba physics, and put forward a possible way of experimentally detecting the orbital texture. Finally, we discuss the analogy by comparing the coexistence of linear Rashba + Dresselhaus effects and Jahn–Teller problems for specific symmetries, which allow for nontrivial spin and orbital textures, respectively. 相似文献
118.
Andrea Salvo Nicola Cicero Rossella Vadalà Antonio Francesco Mottese Daniel Bua Domenico Mallamace 《Natural product research》2016,30(6):657-664
Toxic and essential metals content was determined by inductively coupled plasma mass spectrometry in commercial sea urchins samples from the Mediterranean Sea and Pacific Ocean. Results show that Chilean samples have the highest values of Cd, As, Ni, Cr and V; Spanish samples have the maximum Hg content while Sicilian samples have the lowest content of toxic metals. The toxic metal traces were compared with the limits of European Community (EC) No. 1881/2006 for bivalve molluscs. All samples exceed Pb and Cd limit levels; regarding Hg levels, only Sicilian and Sardinian samples have Hg content below the EC limits. The dietary intake of toxic and essential elements was evaluated for an adult. Furthermore, our study highlights a correlation between the toxic elements content and the marine environmental conditions of the places of origin even though only the generic FAO fishing area is specified. 相似文献
119.
Cafarchia C Otranto D Campbell BE Latrofa MS Guillot J Gasser RB 《Electrophoresis》2007,28(8):1176-1180
Members of the genus Malassezia are budding yeasts, characterized by a thick cell wall. Recently, these yeasts have received attention as emerging pathogens. They are common commensals on the skin of animals and can become pathogenic under the influence of various predisposing factors. Central to studying their taxonomy, systematics, and ecology and to diagnosis is the accurate identification of species or operational taxonomic units. To overcome the limitations of current phenotypic and biochemical methods of identification, a PCR-coupled SSCP approach, utilizing sequence variation (0.4-33.5%) in short regions (approximately 250-270 bp) of the first internal transcribed spacer (ITS-1) of nuclear ribosomal DNA and the chitin synthase-2 gene (chs-2), was assessed for the identification and differentiation of different species/genotypes of Malassezia, characterized previously by DNA sequencing. Genomic DNA samples (n = 30) from Malassezia isolates cultured from canine skin scrapings were assessed by SSCP analysis of the two different genetic loci, and unequivocal delineation between genotypes and species was achieved. This SSCP approach is considered to provide a practical tool for the rapid and reliable genetic characterization of Malassezia genotypes/species from dogs and for investigating their population genetics and ecology. It will also provide a powerful tool for studies of Malassezia isolates from other animal species. 相似文献
120.
Noemi Bognanni Maurizio Viale Alessia Distefano Rita Tosto Nadia Bertola Fabrizio Loiacono Marco Ponassi Domenico Spinelli Giuseppe Pappalardo Graziella Vecchio 《Molecules (Basel, Switzerland)》2021,26(19)
In the few last years, nanosystems have emerged as a potential therapeutic approach to improve the efficacy and selectivity of many drugs. Cyclodextrins (CyDs) and their nanoparticles have been widely investigated as drug delivery systems. The covalent functionalization of CyD polymer nanoparticles with targeting molecules can improve the therapeutic potential of this family of nanosystems. In this study, we investigated cross-linked γ- and β-cyclodextrin polymers as carriers for doxorubicin (ox) and oxaliplatin (Oxa). We also functionalized γ-CyD polymer bearing COOH functionalities with arginine-glycine-aspartic or arginine moieties for targeting the integrin receptors of cancer cells. We tested the Dox and Oxa anti-proliferative activity in the presence of the precursor polymer with COOH functionalities and its derivatives in A549 (lung, carcinoma) and HepG2 (liver, carcinoma) cell lines. We found that CyD polymers can significantly improve the antiproliferative activity of Dox in HepG2 cell lines only, whereas the cytotoxic activity of Oxa resulted as enhanced in both cell lines. The peptide or amino acid functionalized CyD polymers, loaded with Dox, did not show any additional effect compared to the precursor polymer. Finally, studies of Dox uptake showed that the higher antiproliferative activity of complexes correlates with the higher accumulation of Dox inside the cells. The results show that CyD polymers could be used as carriers for repositioning classical anticancer drugs such as Dox or Oxa to increase their antitumor activity. 相似文献