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cAMP is an ubiquitous second messenger mediating various neuronal functions, often as a consequence of increased intracellular Ca2+ levels. While imaging of calcium is commonly used in neuroscience applications, probing for cAMP levels has not yet been performed in living vertebrate neuronal tissue before.  相似文献   
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We analyse the evolution of a two-stage chemical reaction betweentwo neighbouring plumes of reactants. Under the assumption thatthe plumes are approximately Gaussian we derive a system ofordinary differential equations for the total amount, the centroidand the variance of each reactant. We compare the solution ofthese equations with full numerical simulation of the reaction.Excellent agreement is obtained, with solution of the near-Gaussianmodel requiring considerably less computational effort thanthe full simulations. Of key importance is the yield of thereaction, and we discuss this feature in particular.  相似文献   
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There has been a huge demand on the usage of biomass-derived activated carbon as an electrode and electrocatalyst for energy storage and conversion applications owing to its abundance, high surface area, good chemical stability, low cost, and eco-friendliness. Herein, we report for the first time, activated carbon (AC) derived from Phyllanthus Emblica Leaves (PEL) (Indian gooseberry) biomass as an electrocatalyst for enhancing the bromine electro-kinetics. The AC-anchored graphite felt (AC−GF) showed excellent improvement in the bromine reversibility, which reinforces the overall performance of the zinc bromine redox flow battery (ZBRFB). Specifically, the AC−GF showed significant improvement in voltage efficiency. The flow cell employing AC in the positive electrode showed high Coulombic, voltage, and energy efficiency of 99, 83 and 82 %, respectively at a current density of 30 mA cm−2. Furthermore, the cell showed good cycle performance with 96.43 % Coulombic efficiency retention even after 100 cycles. Thus, the significant improvement in the cell performance unveils the good electrochemical/catalytic activity of the AC and therefore can be used as a potential low-cost electrocatalyst in ZBRFB.  相似文献   
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A scanning Hall probe microscope is used to study flux pinning in a thin superconducting Pb film covering a square array of single-domain Co dots with in-plane magnetization. We show that single flux quanta of opposite sign thread the superconducting film below T(c) at the opposite poles of these dipoles. Depending on the polarity of the applied field, flux lines are attracted to a specific pole of the dipoles, due to the direct interaction with the vortexlike structures induced by the local stray field.  相似文献   
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