Iα → Iβ transition of cellulose under ultrasonic radiation

Aqueous suspensions of dispersed Glaucocystis cellulose microfibrils were sonicated at 4 °C for 3 h, using 24 kHz ultrasonic waves. This treatment induced a variety of ultrastructural defects, as the microfibrils became not only shortened, but also presented substantial damage materialized by kinks and subfibrillation. Upon analysis by X-ray diffraction and ¹³C solid-state NMR spectroscopy, it was found that the initial sample that contained 90 % of cellulose I_α allomorph became, to a large extent, unexpectedly converted into the I_β phase, while the loss of crystallinity was only moderate during the sonication treatment.     

Characteristics of polyurethane-based sustained release membranes for drug delivery

This paper is focused on the preparation and physicochemical characterization of two poly(ester ether urethane)s with rifampicin in their matrix and different molar concentrations of urethane groups. The polyurethanes with rifampicin were processed as asymmetrical microporous membranes by a phase inversion method and characterized by attenuated total reflection — Fourier transform infrared (ATR-FTIR) spectroscopy and differential scanning calorimetry (DSC). The influence of the surface morphology in the release of drug compounds was analyzed by scanning electron microscopy (SEM), atomic force microscopy (AFM), contact angle, and water uptake. The release of rifampicin depends on the molar concentration of urethane groups and also on the surface morphology of the polyurethane membranes. The antibacterial activity was evaluated with S. Epidermidis RP 62 A and P. Aeruginosa ATCC 1544. Finally, the biocompatibility of the polyurethane membranes was studied with human dermal fibroblasts (HDF) to evaluate the potential biomedical applications.      

Ultra‐fast heralded single photon source based on telecom technology

The realization of an ultra‐fast source of heralded single photons emitted at the wavelength of 1540 nm is reported. The presented strategy is based on state‐of‐the‐art telecom technology, combined with off‐the‐shelf fiber components and waveguide non‐linear stages pumped by a 10 GHz repetition rate laser. The single photons are heralded at a rate as high as 2.1 MHz with a heralding efficiency of 42%. Single‐photon character of the source is inferred by measuring the second‐order autocorrelation function. For the highest heralding rate, a value as low as 0.023 is found. This not only proves negligible multi‐photon contributions but also represents one of the best measured values reported to date for heralding rates in the MHz regime. These performances, associated with a device‐like configuration, are key ingredients for both fast and secure quantum communication protocols.

     

Phospholipid-based nonlamellar mesophases for delivery systems: Bridging the gap between empirical and rational design

Phospholipids are ubiquitous cell membrane components and relatively well-accepted ingredients due to their natural origin. Phosphatidylcholine (PC) in particular offers a promising alternative to monoglycerides for lyotropic liquid crystalline (LLC) delivery system applications in the food, cosmetics and pharmaceutical industries, provided its strong tendency to form zero-mean curvature lamellar mesophases in water can be overcome. Higher negative curvatures are usually reached through the addition of a third lipid component, forming a ternary diagram phospholipid/water/oil.     

Toward the understanding of the environmental effects on core ionizations

Experimental X‐ray absorption spectra are extensively used to determine electronic structure of small molecules but remain difficult to exploit for proteins due to the large number of peaks within their spectra. For such complex systems, theoretical tools like quantum mechanics/molecular mechanics methodology can greatly ease the assignment of the spectra. This study presents a systematic methodology to evaluate core‐ionization energies (E_ion) in proteins with the help of the asymptotic projection approach (Glushkov and Tsaune, Z. Vichislit. Matem. Mat. Fiz. 1985, 25, 298; Glushkov, Chem. Phys. Lett. 1997, 273, 122; Glushkov, Chem. Phys. Lett. 1998, 287, 189; Glushkov, J. Math. Chem. 2002, 31, 91; Glushkov, Opt. Spectrosc. 2002, 93, 15). An in‐depth inspection of E_ion of systems of increasing complexity is considered, going from amino acids to polyglycine and to glycine in human serum albumin (HSA). Computational analysis can help to better understand experimental data and to discriminate environmental effects by tracing them back to individual and collective electrostatic contributions. In the present work, it was found that E_ion of alpha carbon of glycine residues in HSA ranges from 285 to 295 eV depending on their surroundings. © 2014 Wiley Periodicals, Inc.     

Isolated boundary singularities of semilinear elliptic equations

Given a smooth domain ${\Omega\subset\mathbb{R}^N}$ such that ${0 \in \partial\Omega}$ and given a nonnegative smooth function ?? on ???, we study the behavior near 0 of positive solutions of ???u?=?u ^q in ?? such that u =? ?? on ???\{0}. We prove that if ${\frac{N+1}{N-1} < q < \frac{N+2}{N-2}}$ , then ${u(x)\leq C |x|^{-\frac{2}{q-1}}}$ and we compute the limit of ${|x|^{\frac{2}{q-1}} u(x)}$ as x ?? 0. We also investigate the case ${q= \frac{N+1}{N-1}}$ . The proofs rely on the existence and uniqueness of solutions of related equations on spherical domains.     

Compressive Wave Computation

This paper presents a method for computing the solution to the time-dependent wave equation from the knowledge of a largely incomplete set of eigenfunctions of the Helmholtz operator, chosen at random. While a linear superposition of eigenfunctions can fail to properly synthesize the solution if a single term is missing, it is shown that solving a sparsity-promoting ℓ ₁ minimization problem can vastly enhance the quality of recovery. This phenomenon may be seen as “compressive sampling in the Helmholtz domain.”     

Relative frames on J-holomorphic curves

The aim of this work is to prove that any non-constant J-holomorphic disc with its boundary in a given Lagrangian submanifold can be decomposed in homology into a sum of finitely many J-holomorphic simple discs with the same Lagrangian boundary condition. As a consequence, in dimension higher than 6, any generic J-holomorphic disc is multicovered.     

Large variation in the boundary-condition slippage for a rarefied gas flowing between two surfaces

We study the slippage of a gas along mobile rigid walls in the sphere-plane confined geometry and find that it varies considerably with pressure. The classical no-slip boundary condition valid at ambient pressure changes continuously to an almost perfect slip condition in a primary vacuum. Our study emphasizes the key role played by the mean free path of the gas molecules on the interaction between a confined fluid and solid surfaces and further demonstrates that the macroscopic hydrodynamics approach can be used with confidence even in a primary vacuum environment where it is intuitively expected to fail.     

Stress clamp experiments on multicellular tumor spheroids

The precise role of the microenvironment on tumor growth is poorly understood. Whereas the tumor is in constant competition with the surrounding tissue, little is known about the mechanics of this interaction. Using a novel experimental procedure, we study quantitatively the effect of an applied mechanical stress on the long-term growth of a spheroid cell aggregate. We observe that a stress of 10 kPa is sufficient to drastically reduce growth by inhibition of cell proliferation mainly in the core of the spheroid. We compare the results to a simple numerical model developed to describe the role of mechanics in cancer progression.