Phosphine‐Directed CH Borylation Reactions: Facile and Selective Access to Ambiphilic Phosphine Boronate Esters

Ambiphilic ligands have received considerable attention over the last two decades due to their unique reactivity as organocatalysts and ligands. The iridium‐catalyzed C? H borylation of phosphines is described in which the phosphine is used as a directing group to provide selective formation of arylboronate esters with unique scaffolds of ambiphilic compounds. A variety of aryl and benzylic phosphines were subjected to the reaction conditions, selectively providing stable, isolable boronate esters upon protection of the phosphine as the borane complex. After purification, the phosphine‐substituted boronate esters could be deprotected and isolated in pure form.     

Radiological dose assessment of naturally occurring radioactive materials in concrete building materials

Previous studies have shown that the natural radioactivity contained in building materials have significantly influenced the dose rates in dwelling. Exposure to natural radiation in building has been of concerned since almost 80 % of our daily live are spend indoor. Thus, the aim of the study is to assess the radiological risk associated by natural radioactivity in soil based building materials to dwellers. A total of 13 Portland cement, 46 sand and 43 gravel samples obtained from manufacturers or bought directly from local hardware stores in Peninsular of Malaysia were analysed for their radioactivity concentrations. The activity concentrations of ²²⁶Ra, ²³²Th and ⁴⁰K in the studied building materials samples were found to be in the range of 3.7–359.3, 2.0–370.8 and 10.3–1,949.5 Bq kg^?1 respectively. The annual radiation dose rates (μSv year^?1) received by dwellers were evaluated for 1 to 50 years of exposure using Resrad-Build Computer Code based on the activity concentration of ²²⁶Ra, ²³²Th and ⁴⁰K found in the studied building material samples. The rooms modelling were based on the changing parameters of concrete wall thickness and the room dimensions. The annual radiation dose rates to dwellers were found to increase annually over a period of 50 years. The concrete thicknesses were found to have significantly influenced the dose rates in building. The self-absorption occurred when the concrete thickness was thicker than 0.4 m. Results of this study shows that the dose rates received by the dwellers of the building are proportional to the size of the room. In general the study concludes that concrete building materials; Portland cements, sands, and gravels in Peninsular of Malaysia does not pose radiological hazard to the building dwellers.     

Zeaxanthin Production by Novel Marine Isolates from Coastal sand of India and its Antioxidant Properties

Zeaxanthin carotenoids are class of commercially important natural products and diverse biomolecules produced by plants and many microorganisms. Bacteria often produce a cocktail of polar and nonpolar carotenoids limiting their industrial applications. Marine members of the family Flavobacteriaceae are known to produce potential carotenoids such as astaxanthin and zeaxanthin. A few bacterial species have been reported for the predominant production zeaxanthin. Here, we report the molecular identification of the zeaxanthin as a major carotenoid produced by two novel bacteria (YUAB-SO-11 and YUAB-SO-45) isolated from sandy beaches of South West Coast of India and the effect of carbon sources on the production of zeaxanthin. The strains were identified based on the 16S rRNA gene sequencing as a member of genus Muricauda. The closest relatives of YUAB-SO-11 and YUAB-SO-45 were Muricauda aquimarina (JCM 11811^T) (98.9 %) and Muricauda olearia (JCM 15563^T) (99.2 %), respectively, indicating that both of these strains might represent a novel species. The highest level of zeaxanthin production was achieved (YUAB-SO-11, 1.20?±?0.11 mg g^?1) and (YUAB-SO-45, 1.02?±?0.13 mg g^?1) when cultivated in marine broth supplemented with 2 % NaCl (pH 7) and incubated at 30 °C. Addition of 0.1 M glutamic acid, an intermediate of citric acid cycle, enhanced the zeaxanthin production as 18 and 14 % by the strains YUAB-SO-11 and YUAB-SO-45 respectively. The zeaxanthin showed in vitro nitric oxide scavenging, inhibition of lipid peroxidation, and 2,2-diphenyl-1-picryl hydrazyl scavenging activities higher than the commercial zeaxanthin. The results of this study suggest that two novel strains YUAB-SO-11 and YUAB-SO-45 belonging to genus Muricauda produce zeaxanthin as a predominant carotenoid, and higher production of zeaxanthin was achieved on glutamic acid supplementation. The pigment showed good in vitro antioxidant activity, which can be exploited further for commercial applications.     

Revisiting queueing output processes: a point process viewpoint

After some historical notes concerning queueing output processes N _dep??, the paper discusses methods for establishing asymptotic linear relations for var??N _dep??(0,t], whether in the crude form B ₁ t or the more detailed form B ₁ t+B ₀+o(1) for t→∞. The crude form holds whenever the process N _adm of customers admitted to service has a linear asymptote, and then (var??N _dep??(0,t])/t and (var??N _adm(0,t])/t share a common limit (that may be infinite) in stationary G/G/k/K systems. A standard integral formula for the variance of a stationary orderly point process shows that, if N _dep?? is a renewal process whose generic lifetime X has finite second moment, then B ₁=(var??X)/([E(X)]²), and the more detailed linear asymptote holds when E(X ³) is finite. Geometric ergodicity of the queue size process Q(?) in stationary M/M/k/K systems establishes that the more detailed linear asymptote is true for them. It is conjectured that var??N(0,t]～B ₁ t for any stationary point process N possessing an embedded regenerative structure.     

Accessing Ambiphilic Phosphine Boronates through C−H Borylation by an Unforeseen Cationic Iridium Complex

Ambiphilic molecules, which contain a Lewis base and Lewis acid, are of great interest based on their unique ability to activate small molecules. Phosphine boronates are one class of these substrates that have interesting catalytic activity. Direct access to these phosphine boronates is described through the iridium‐catalyzed C?H borylation of phosphines. An unconventional cationic iridium catalyst was identified as optimal for a range of phosphines, providing good yields and selectivity across a diverse class of phosphine boronates (isolated as the borane‐protected phosphine). A complimentary catalyst system (quinoline‐based silane ligand with [(COD)IrOMe]₂) was optimal for biphenyl‐based phosphines. Selective polyborylation was also shown providing bis‐ and tris‐borylated phosphines. Deprotection of the phosphine boronate provided free ambiphilic phosphine boronates, which do not have detectable interactions between the phosphorus and boron atoms in solution or the solid state.     

The Busy Period of the M/GI/∞ Queue

An equation for the distribution Z() of the duration T of the busy period in a stationary M/GI/ service system is constructed from first principles. Two scenarios are examined, being distinguished by the half-plane Re()>₀ for some ₀0 in which the generic service time random variable S, always assumed to have a finite mean E(S), has an analytic Laplace–Stieltjes transform E(e^–S ). If ₀<0 then E(e^–T ) is analytic in a half-plane (₁,), where ₀₁<0 and ₁ is determined by the distribution of S; then for any 0<s<|₁|.When ₀=0, E(e^–T ) is analytic in (0,), and now more is known about T. Inequalities on the tail () are used to show that for any 1, E(T ) is finite if and only if E(S ) is finite. It follows that the point process consisting of the starting epochs of busy periods is long range dependent if and only if E(S ²)=, in which case it has Hurst index equal to [frac12](3–), where is the moment index of S.If also the tail (x)=Pr{Sx} of the service time distribution satisfies the subexponential density condition ₀ ^x (x–u) (u)du/ (x)2E(S) as x, then (x)/ (x)e^E(S), where is the arrival rate.     

Defect-suppressed atomic crystals in an optical lattice

We present a coherent filtering scheme which dramatically reduces the site occupation number defects for atoms in an optical lattice by transferring a chosen number of atoms to a different internal state via adiabatic passage. With the addition of superlattices it is possible to engineer states with a specific number of atoms per site (atomic crystals), which are required for quantum computation and the realization of models from condensed matter physics, including doping and spatial patterns. The same techniques can be used to measure two-body spatial correlation functions.     

Single atom transistor in a 1D optical lattice

We propose a scheme utilizing a quantum interference phenomenon to switch the transport of atoms in a 1D optical lattice through a site containing an impurity atom. The impurity represents a qubit which in one spin state is transparent to the probe atoms, but in the other acts as a single atom mirror. This allows a single-shot quantum nondemolition measurement of the qubit spin.     

Pedestrian-Induced Bridge Instability: The Role of Frequency Ratios

Radiophysics and Quantum Electronics - The emergence of the pedestrian-induced bridge instability is conventionally associated with crowd synchrony; however, this view has been challenged. In this...