Copper(I) catalyzed regioselective asymmetric alkoxyamination of aryl enamide derivatives

The copper(I) catalyzed reaction of an enamide with an iminoiodane, in the presence of an alcohol, triggers the direct alkoxyamination of the double bond. This transformation represents a straightforward access to α-amino aminals in a completely regio- and diastereoselective manner. Use of a chiral Box ligand allows this reaction to be carried out in an enantioselective fashion.     

Tandem postsynthetic modification of metal-organic frameworks using an inverse-electron-demand Diels-Alder reaction

A postsynthetic modification (PSM) scheme for metal-organic frameworks (MOFs) has been developed using a tetrazine-based "Click" reaction. It was found that the efficacy of this modification procedure was dependent on the MOF topology and, in the case of an isoreticular MOF (IRMOF) system, required the formation of a mixed-ligand IRMOF with a suitable ratio of 1,4-benzenedicarboxylate (BDC) and an olefin-tagged BDC derivative. On the basis of the versatile use of tetrazine "Click" chemistry in bioconjugate chemistry, we expect that this scheme will prove to be a useful reaction for preparing functionalized materials, including MOFs.     

Development of a convenient synthetic route to aminochromenes via Buchwald C-N coupling

A convenient new synthetic route to p-aminophenylaminobenzo- and naphthopyrans was developed via palladium-catalyzed C-N coupling. It was demonstrated that novel targeted aminoderivatives reveal photochromic properties. The structure of intermediate p-nitrophenylaminochromenes was confirmed by X-ray crystallographic analysis.     

Surfactant effects on pH-controlled synthesis of nickel hydroxides

The aim of the present work is to determine at 60 °C, the influence of the specific nature of nickel salt and pH on nickel hydroxide features such as crystallographic structure and morphology. Within the range 8 ≤ pH ≤ 11.5, a home-made nickel functionalized surfactant, nickel di-dodecylsulfate Ni(C₁₂H₂₅SO₄)₂ is compared to usual salts (nickel nitrate Ni(NO₃)₂ and nickel sulfate NiSO₄). In both cases, a sharp transition appears for pH about 10. In the classic salt case, the transition mainly affects morphology, that could be evidenced by the crosschecking of complementary techniques as SEM and nitrogen gas adsorption. For pH < 10, β-Ni(OH)₂ platelets are yielded, whereas more basic conditions lead to randomly aggregated nano-grains of badly crystallized β hydroxide. Inversely, by employing the functionalized surfactant, 2D morphology is maintained in the whole pH-range, but the crystal structure is pH-controlled ( phase with interlamellar dodecylsulfate for pH ≤ 9.5, and β phase for pH ≥ 10.5).     

Functionalization of aminocrown ethers with [2H]-chromene units by Buchwald-Hartwig C-N coupling for constructing of photoswitchable molecular devices

Functionalization of the diaminodibenzocrown ethers with 2H-[1]benzopyrane and 3H-naphtho[2,1-b]pyrane units by Buchwald-Hartwig C-N coupling was developed. It is demonstrated that the novel molecule possesses photochromic properties that can be modified by the complex formation process.     

Studies in the eburnane series: a new dimerization process

The behaviour of the synthetic (−)-16-(aminomethyl)eburnamenine (prepared from apovincamine) with formaldehyde was studied. Carrying out the reaction in acetic acid led to an original dimer, while in trifluoroacetic acid a 12-functionalized eburnamonine was isolated.     

Acerolide, a new cytotoxic cembranolide from the soft coral Pseudopterogorgia acerosa

A new cembranolide, acerolide (1) together with the known compound pseudopterolide (2) were isolated from the 2-propanol extract of the soft coral Pseudopterogorgia acerosa. The structure of 1 was determined on the basis of detailed spectroscopic analysis. Compound 1 showed moderate in vitro cytotoxicity against a panel of 14 tumor cell lines.     

Correction to: EQRAIN: uranium and plutonium interlaboratory exercises from 1997 to 2016—comparison to ITVs-2010

Journal of Radioanalytical and Nuclear Chemistry - In the original publication of the article, the values of u(s), u(r) and ITV for HKED were published incorrectly in Table&nbsp;6.