MS-Xα calculations of the electron affinities and ionization potentials of some heavy metals and their hydrides and fluorides

MS -Xα calculations have been performed for the neutral species and the transition states for the positive and negative ions of the heavy metal atoms Mo, W, Re, Ir, Pt, and U and their diatomic hydrides and fluorides. Both nonspin-polarized and spin-polarized calculations were performed. The main purpose of this study was to gain insight into which negative ion species might be preferable to try to prepare for use in ion sources for tandem accelerators.     

Tests of quantum chromodynamics and a direct measurement of the strong coupling constant αs at √s=30 GeV

We report the measurement of the reaction e⁺ + e^? → hadronic jets at a center-of-mass energy √s=30 GeV using the MARK-J detector at PETRA. By measuring the energy and angular distribution of both neutrals and charged particles we were able to isolate unambiguously the three-jet events in a kinematic region where the backgrounds from q$\text{q}$ and phase space contributions and other processes are small. Various comparisons of the data with quantum chromodynamics were made. The relative yield of three-jet events and the shape distribution of the events enable us to determine α_s = 0.23 ± 0.02 (statistical error) with a systematic error of ± 0.04.     

Computation of Hele-Shaw flows with free boundaries

A novel method for calculation of Hele-Shaw flows with receding free boundaries is presented. The method is applied to flows with suction from a point sink and to flow in a channel with parallel walls. In each case the unknown fluid region is mapped conformally onto the unit disc, the free boundary being mapped onto the unit circle. This mapping, which is a function of position and time, is calculated numerically at points on the unit circle using a version of the boundary integral method. The free boundary is thus found without explicit calculation of the pressure at internal points, and the computation times are much less than those for other numerical methods for this problem. Numerical results are compared with explicit analytic solutions for several test problems.     

'Genetics home reference': helping patients understand the role of genetics in health and disease

The surge of information generated by the Human Genome Project has left many health professionals and their patients struggling to understand the role of genetics in health and disease. To aid the lay public and health professionals, the US National Library of Medicine developed an online resource called 'Genetics Home Reference' (GHR), located at http://ghr.nlm.nih.gov/. Launched in April 2003, GHR's goal is to help the public interpret the health implications of the Human Genome Project. It bridges the clinical questions of consumers and the rich technical data emerging from the sequenced human genome. The GHR web site is designed for easy navigation among summaries for genetic conditions and the related gene(s) and chromosome(s). This design strategy enhances the user's appreciation of how genes, chromosomes, and conditions are interrelated.     

On the Homology and Fiber Cone of Ideals

In this article, we give a unified approach for several results concerning the fiber cone. Our novel idea is to use the complex C(x _k , ? _{I 1; I 2} , (1, n)). We improve earlier results obtained by several researchers and get some new results. We give a more general definition of ideals of minimal multiplicity and of ideals of almost minimal multiplicity. We also compute the Hilbert series of the fiber cone for these ideals.     

Quadratic transform of complete ideals in regular local rings

In an upcoming article we study harmonic analysis on the quantum E(2) group within an algebraic framework: we explicitly construct Fourier transforms between quantum E(2) and its Pontryagin dual, involving q-Bessel functions as kernel, prove Plancherel &; inversion formulas etc. In the present paper we propose an algebraic setting in which to perform harmonic analysis on non-compact, non-discrete quantum groups and in particular on quantum E(2). We are mainly concerned with the construction of positive and faithful invariant functionals on an algebraic level, KMS properties, etc.     

Size‐dependent Tumor Response to Photodynamic Therapy and Irinotecan Monotherapies Revealed by Longitudinal Ultrasound Monitoring in an Orthotopic Pancreatic Cancer Model

Longitudinal monitoring of tumor size in vivo can provide important biological information about disease progression and treatment efficacy that is not captured by other modes of quantification. Ultrasound enables high‐throughput evaluation of orthotopic mouse models via fast acquisition of three‐dimensional tumor images and calculation of volume with a reasonable degree of accuracy. Herein, we compare orthotopic pancreatic tumor volume measurements determined by ultrasound with volume measured by calipers and tumor weight, and found strong correlations between the three modalities over a large range of tumor sizes, suggesting ultrasound can accurately quantify tumor volumes in this model. Furthermore, we demonstrate the unique ability of longitudinal treatment monitoring to reveal a tumor size‐dependent response to Benzoporphyrin Derivative photodynamic therapy (BPD‐PDT) and irinotecan. Small tumors (5–35 mm³) were found to respond well to a single round of PDT, while large tumors (35–65 mm³) showed no response to the same treatment. These results highlight the role that tumor size can play in preclinical interpretation of treatment response and more generally suggest that careful evaluation of subtle biological features such as this must be carefully considered in order to grant a more comprehensive understanding of disease biology in vivo.     

Strong coupling approach to actinide metals

We present a strongly correlated approach to the electronic structure of actinide metals by deriving a low-energy Hamiltonian H[over] under the assumption that kinetic energy is small compared to Coulomb and spin-orbit interactions. The H[over]Pu for Pu metal is similar to the models used for Ce and other lanthanides but qualitatively different from the H[over] presented for the rest of the actinides. With H[over]Pu, we computed the photoemission spectrum and specific heat for alpha and delta-Pu and found good agreement with experiment.