Chemical constituents isolated from Zygophyllum melongena Bunge growing in Mongolia

We report the first investigation of the chemical constituents of Zygophyllum melongena Bunge, a species growing in Mongolia. The quinovic acid glycosides 3-O-(β-D-glucopyranosyl)quinovic acid and 3-O-(β-D-glucopyranosyl)quinovic acid (28→1)-(β-D-glucopyranosyl) ester were identified in the chloroform fraction along with the flavonoid glycoside astragalin. The n-butanol fraction contained (+)-D-pinitol as the major component, a cyclitol with anti-diabetic properties. The structures of the isolated natural products were confirmed using ESI-MS and NMR spectroscopy (¹H, ¹³C, COSY, HSQC, HMBC, NOESY and ROESY). This is the first report of the isolation of (+)-D-pinitol from the genus Zygophyllum.     

Study of alkaloids of Siberian and Altai flora. 8. Crystal and molecular structure of elatidal methylimine hydrate

The crystal and molecular structure of elatidal methylimine hydrate was established by X-ray diffraction analysis and a previous assumption of the E configuration of the methylimino group was confirmed.     

Study of alkaloids of the Siberian and Altai flora. 9. Synthesis of amino derivatives of elatidine

New secondary-tertiary diamines were prepared from elatidal imines with primary amino alcohols, derivatives of natural amino acids of the S-series. N-Methylation of the diamines yielded bi-tertiary diamines unable to undergo quaternization with MeI due to steric hindrance.