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991.
992.
An electrorefractive index-controllable guide/antiguide optical intensity modulator has been created and characterized. The operating mechanism, beam propagation method simulation, device design and fabrication, and calculated and experimental results of this guide/antiguide modulator are given. The operational principle of the modulator is based on the field-induced waveguide (FIG) concept; that is, electric-field-induced refractive index changes cause the waveguide to be turned on and off electrically. The modulator is formed with a central narrow FIG electrode sandwiched between two antiguide electrodes. The electrooptic effects, along with carrier effects, have been exploited to adjust the refractive index under the guide and adjacent antiguide electrodes by changing reverse biases applied to them. The modulation is determined mainly by changing the lateral refractive index profiles. In the on state, a waveguide is formed under the central electrode, and the input light propagates along this waveguide. To realize the best off state, an antiguide situation is created that causes the light to diffract out of the central guide rapidly. An on/off ratio larger than 23 dB, a propagation loss 1 dB, and a record optical bandwidth from 1.0 to 1.55 m have been obtained for this modulator. 相似文献
993.
This work estimated the porosities of activated sludge flocs, cationic polyelectrolyte flocculated, based on free-settling tests, buoyant weight measurements, and confocal laser scanning microscope (CLSM) tests. The extent of advective flow was estimated based on bubble-tracking test. The former two measurements suggested a close-to-unity porosity, that is, an extremely void floc interior. Meanwhile, the latter two tests recommended a dense floc interior with a porosity less than 64%. A discrepancy exists between the porosities estimated by various tests. A floc model was proposed based on the understanding that a vast amount of bound water in the floc was regarded as void in buoyant weight measurement, but was impermeable for advective flow. The distribution rather than the mean value of the porosity controls the advective flow. There existed no simple correlation between the porosities measured by different tests. 相似文献
994.
Reaction monitoring of succinylation of collagen with matrix-assisted laser desorption/ionization mass spectrometry 总被引:1,自引:0,他引:1
Kim SH Lee JH Yun SY Yoo JS Jun CH Chung KY Suh H 《Rapid communications in mass spectrometry : RCM》2000,14(22):2125-2128
Succinylated collagen was synthesized by the reaction of collagen with succinic anhydride under basic conditions for one hour. Using the matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) technique, the reaction products were directly identified without multi-step separation processes. MALDI-MS monitored the reaction more accurately than the conventional method of sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). From the change in molecular mass during the reaction, it is observed that about 28 succinyl groups are attached to the collagen strand. 相似文献
995.
The theoretical justification of the model potential method is studied in some detail. The correct equations within the framework of Roothaan's open-shell scheme are derived and the approximations necessary to get a workable method are discussed. Analysis of the local part of the model potential suggests a new analytical form for it. The new expression is theoretically more consistent than the original one, and it can be determined in a more straightforward way. A basis set approximation, which is particularly suitable for approximate evaluation of two-electron integrals when only valence orbitals are involved, is discussed and tested with encouraging results. The ideas are tested on the Fe and I atoms. 相似文献
996.
Escherichia coli heat-labile enterotoxin (LT), which causes a characteristic diarrhea in humans and animals, is a strong mucosal immunogen and has powerful mucosal adjuvant activity towards coadministered unrelated antigens. Here we report the different mucosal adjuvanticity of nontoxic LT derivatives, LTS63Y and LTdelta110/112, generated by immunizing through two different mucosal routes. Intragastric (IG) immunization with Helicobacter pylori urease alone resulted in poor systemic IgG and IgA responses and no detectable local secretory IgA, but IG co-immunization with urease and LTdelta110/112 induced high titers of urease-specific local secretory IgA and systemic IgG and IgA, comparable to those induced by wild-type LT. LTS63Y showed far lower adjuvant activity towards urease than LTdelta110/112 in IG immunization, but was more active than LTdelta110/112 in inducing immune responses to urease by intranasal (IN) immunization. LTdelta110/112 predominantly enhanced the induction of urease-specific IgG1 levels following IG immunization, whereas LTS63Y induced high levels of IgG1, IgG2a and IgG2b following IN immunization. In addition, quantitative H. pylori culture of stomach tissue following challenge with H. pylori demonstrated a 90-95% reduction (p < 0.0002) in bacterial burden in mice immunized intranasally with urease using either mutant LT as an adjuvant. These results indicate that the mechanism(s) underlying the adjuvant activities of mutant LTs towards coadmnistered H. pylori urease may differ between the IN and IG mucosal immunization routes. 相似文献
997.
The structure of macrocyclic ligand complex, (5, 7, 12, 14-tetraethyl-7, 14-dimethyl-1, 4, 8, 11-tetraazacyclotetra decane)·NiII·(ClO4)2 has been determined by X-ray diffraction with three dimensional counter data. This compound, C20H44N4NiII·(ClO4)2, crystallizes in orthorhombic space group Pbca, with cell parameters a=14.369, b=11.752, c=16.207 A, V=2736.8 A3, determined from Syntex Pl autodiffractomter. The formula weight (598.21) and a measured density of 1.45 gm cm?3 (by flotation) indicate the presence of four molecules per unit cell (Dc=1.452 gm cm?3). The structure was solved, using Patterson and Fourier methods and refined by full-matrix least-squares techniques to a reliability index, R(F) of 0.09, based on 1480 independent observed data corrected for absorption, L-p factors. In this molecule, in addition to the usual covalent and ionic bonds, there exist two hydrogen bonds between the perchlorate ions and the amine groups. The Ni and the four N atoms are coplanar. The six membered ring subtends a larger angle (93.5(3)°) over the Ni atom than the five membered ring (86.5(3)°) does. The former belongs to the chair form and the latter pertains to the gauche form. 相似文献
998.
We demonstrate here, for the first time, that non-aqueous capillary electrophoresis (NACE) can be interfaced with any ultra-low-temperature (ULT) separation method and 77 K fluorescence spectroscopy (FS). This novel ULT-NACE-FS system consists of a modular CE system, a dry ice bath, and instrumentation for 77 K fluorescence detection. The ULT-NACE method serves to separate structurally similar molecules by a combination of a low electrophoresis current and a high voltage at approximately -70 degrees C. When the ULT-NACE-separated analytes move into the quartz Dewar flask and traverse into the capillary detection window, liquid nitrogen was added, thus freezing the separating analyte zones, allowing the collection of 77 K fluorescence spectra for on-line spectral fingerprint identification. The first application of the ULT-NACE-FS system is described for the analysis of photo-converted analytes of trans-resveratrol; prospects and future applications of ULT-NACE-FS are also briefly addressed. 相似文献
999.
A model for the mechanism of the Gel permeation chromatographic separation of a polymer and a new calibration method have been developed, based on the exclusion of the polymer from the pores of the packing material. We propose that the calibration curve a plot of log (1—√K) versus log (molecular weight), where K is the elution volume coefficient, is close to linear over a K range of 0.15–0.85. We compare our procedure with that of Haller for various sets of data. Our procedure is generally better with lower standard deviations. When extrapolated, it gives a critical permeation size characteristic of the glass column packings. 相似文献
1000.
Woo Jin Chung 《Tetrahedron letters》2004,45(28):5403-5406
New fluorinated silyl enol ethers with various trialkylsilyl groups were synthesized. Various fluorinated β-hydroxy ketones were synthesized by Lewis acid promoted aldol reaction of silyl enol ethers with diverse aldehydes. Reactivity of various trialkylsilyloxy groups toward Lewis acid was also studied. 相似文献