磷酰化与非磷酰化蛋氨酸水溶液的脉冲辐解研究

蛋氨酸能快速清除导致辐射损伤的·OH自由基，在放射生物学上是一类很重要的辐射保护剂，因此，引起了人们的广泛关注［l一到．生物大分子的磷酸化作用亦越来越受到重视，特别是近年来基因调控研究发现，许多蛋白质和生物酶只有被磷酸化氧化才具有生理活性，文献［4－6］报导蛋     

Aerobic oxidation assisted by ligand-free palladium catalysts

Aerobic oxidation of electron-rich benzylic and phenyl allylic alcohols was achieved with high yields with only 0.1 mol.% of Pd(OAc)2 catalyst in the absence of any ligand. This procedure was expected to be valuable for realistic industrial-scale applications from both economic as well as environmental points of view.     

微波照射合成不对称1，4－二氢吡啶的研究

微波照射合成不对称１，４－二氢吡啶的研究张雅文，沈宗旋，潘备，杨海康，陆新华，陆澄容（苏州大学化学系苏州２１５００６）关键词缩合，二氢吡啶，微波Ｈａｎｔｚｓｃｈ合成是制备１，４－二氢吡啶的经典方法。这一合成的改进方法之一是３－氨基巴豆酸酯与醛和乙酰乙...     

Analysis of flavonoids in <Emphasis Type="Italic">Ginkgo biloba</Emphasis> L. and its phytopharmaceuticals by capillary electrophoresis with electrochemical detection

A high-performance capillary electrophoretic (CE) method with electrochemical detection (ED) has been developed for determination of the pharmacologically active flavonoids in Ginkgo biloba L. and phytopharmaceuticals containing its extract. Epicatechin, catechin, rutin, apigenin, luteolin, and quercetin are important flavonoids in this plant. Operated in a wall-jet configuration, a 300 micro m diameter carbon-disk electrode was used as working electrode with good response to the six analytes at +1000 mV (relative to the SCE). Under the optimum conditions, the analytes were separated within 22 min in a borax buffer (pH 9.0). Excellent linearity was obtained over two orders of magnitude and detection limits (S/N=3) ranged from 1.4 x 10(-7) to 5.0 x 10(-7) g mL(-1) for all six analytes. The method was successfully used for assay of Ginkgo biloba L. and its phytopharmaceuticals after a relatively simple extraction procedure; the results obtained were satisfactory.     

Carbon-13 spectra of some tetrahydropyridines. The structure of the tetrahydropyridines from 3,5-lutidine 1-oxide and mercaptans in acetic anhydride

The reaction of 3,5-lutidine 1-oxide ( 1 ) with t-butyl mereaptan in acetic anhydride, with or without triethylamine, was reinvestigated. There was obtained 2-t-butylthio-3,.5-lutidine as the major product, a small quantity of 3-(t-bulylthio)methyl-5-picoline, 1-acetyl-2,3-diacetoxy-3,5-dirnethyl-6-t-butylthio-1,2,3,6-tetrahydropyridine (which represents a structure revision) and l-acetyl-2,6-dihydroxy-3-t-butylthio-3,5-dimethyl-1,2,3,6-tetrahydropyridine. A similar reaction of 1 with 1-adamantyl mercaptan furnished 2-(l-adamantylthio)-3,5-lutidine and 1-acetyl-2,3-diacetoxy-3,5-dimethyl-6-(1-adamantylthio)-1,2,3,6-tetrahydropyridine. The structures of these new tetrahydropyridines were established primarily by carbon-13 nmr spectra.     

ATR-FTIR study of Bacillus sp. and Escherichia coli settlements on the bare and Al2O3 coated ZnSe internal reflection element

FTIR-ATR has been used for understanding the interaction between bacteria and surfaces in the adsorption progress.     

Triorganosilyl Ethers of Benzaldehyde,m-Methoxybenzaldehyde and Anisoles

Synthesis of six new triorganosiloxybenzaldehydes, two m-methoxy-(triorganosiloxy)benzaldehydes, and seven methoxy(triorganosiloxy)benzenes are reported. From comparison of the stability of these compounds in the atmosphere, it is concluded that formyl group shows unfavorable influence and methoxy group shows favorable influence on the stability of these compounds. The oposite influences of these two groups on phenoxysilane linkage seems to connect with the oposite directiones of inductive effect of formyl group and resonance effect of methoxy group on the benzene ring.     

Voltammetric Detector for Liquid Chromatography: Determination of Triclosan in Rabbit Urine and Serum

A flow-electrolytic cell containing a strand of carbon fibers has been designed and characterized for use in a voltammetric detector for high-performance liquid chromatography. The detector was used for determination of triclosan (2,4,4-trichloro-2-hydroxydiphenyl ether) in rabbit serum and urine. Analysis of rabbit serum and urine 1 day and 1 to 5 days, respectively, after ingestion of oral triclosan revealed that the concentration of triclosan was higher than for control serum and urine. The concentration reached maximum levels after 6 h and 34 h or 44 h in serum and urine, respectively. When triclosan was determined in rabbit samples with the method proposed the results obtained were comparable with those obtained by high-performance liquid chromatography with ultraviolet detection.