Polysaccharides of algae 68. Sulfated polysaccharides from the Kamchatka brown alga Laminaria bongardiana

Several fucoidan fractions were isolated from the biomass of the Kamchatka brown alga Laminaria bongardiana by hot water extraction followed by anion-exchange chromatography. Fucoidans were found to be composed of l-fucose, d-galactose, and sulfate as the major components, whereas d-xylose, d-mannose, d-glucuronic acid, and acetate were detected as the minor constituents. Highly sulfated fucoidan fractions F-2 and F-3 were solvolytically desulfated by heating in dimethyl sulfoxide in the presence of pyridine. The structures of native and desulfated polysaccharides were investigated by the methylation analysis and NMR spectroscopy. It was shown that F-2 contains fucan sulfate, the backbone of which is made of 1→3-linked α-l-fucopyranose residues with single α-l-Fucp branches at positions 2 and sulfate groups predominantly at positions 4. Sulfated fucoglucuronomannan, fucoglucuronan, and fucogalactan were detected in F-2 as concomitant polysaccharides. Fucan sulfate and sulfated fucogalactan were the major components of the fraction F-3. The anticoagulant properties of fucoidan fractions were assessed. It was demonstrated that the activity of the fraction F-3 is comparable with that of low-molecular-weight heparin (enoxaparin), whereas the activity of total fucoidan F and the fraction F-2 is ~2/3 and ~1/2, respectively, of the activity of F-3, which is in accordance with the lower sulfate content in these samples. Desulfated preparations F-2deS and F-3deS were completely devoid of anticoagulant activity.

     

Extracting model parameters from experimental data using the minimum information principle

A method is described for extracting model parameters of a physical process from statistical experimental data based on the minimum information principle. Potentialities of the method are studied by examples of regular and chaotic processes simulated by the transport and diffusion equation and by the logistic mapping.     

Synthesis of a disaccharide of phenolic glycolipid from Mycobacterium leprae (PGL-I) and its conjugates with bovine serum albumin

Russian Chemical Bulletin - Terminal disaccharide fragment of phenolic glycolipid from Mycobacterium leprae (PGL-I) was synthesized as a glycoside with 4-(2-aminoethoxy)phenyl aglycon. The obtained...     

Search for Z* boson at ATLAS detector

We present the results of the search for new excited Z* boson at ATLAS detector in 2011. Results are based on the analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.9 fb^?1 in the dielectron channel and 5.0 fb^?1 in the dimuon channel. Since good agreement between experimental data and expectation of the Standard Model is observed in both channels, the existence of Z* is excluded with 95 percent confidence level for all masses below 2.20 TeV. The plans for Z* search in 2012 are discussed.     

Synthesis of deutero analogs of α-methyl-2,3,4,6-tetra-O-methyl-D-glucopyranoside

Conclusions The 1d-, 2d-, 3d-, 4d-, 5d-, and 6d₂--methyl-2,3,4,6-tetra-O-methyl-D-glucopyranosides, containing over 90% of deuterium were synthesized.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 1, pp. 201–204, January, 1977.     

Anomalous Decrease in the Threshold of Stimulated Raman Scattering near the Surface of Liquid Nitrogen

JETP Letters - An anomalously strong (up to 13 times) reduction of the threshold of the stimulated Raman scattering of 15-ps laser pulses in liquid nitrogen has been found when moving the caustic...     

Density-functional theory calculation on the nitrogen oxide reduction reaction with carbon monoxide on a titanium dioxide nanocluster

The density functional theory was used for simulation of the NO reduction reaction with carbon monoxide on a reduced Ti₈O₁₅ nanocluster. The reaction proceeds on oxygen vacancies formed via the removal of terminal or bridging O atoms. In the case of adsorption of two NO molecules of such sites, a stable adsorption complex with the bidentate ligand ‥ONNO is produced. When a CO molecule approaches one of the O atoms of this cycle, the following exothermic reaction yielding N₂ and CO₂ adsorbed on the Ti₈O₁₆ cluster takes place: 2NO+ CO + Ti₈O₁₅ → N₂+ Ti₈O₁₆ · CO₂. The proposed model of the reaction agrees well with experimental data.     

Reaction of polyhaloalkyl-substituted chromones, pyrones, and furanones with salicylaldehydes as a direct route to fused 2H-chromenes

Polyhaloalkyl-substituted chromones, gamma-pyrones, and beta-furanones react with salicylaldehydes in the presence of piperidine to give a wide variety of fused 2H-chromenes in good yields. This novel annulation reaction presumably proceeds by a tandem intermolecular oxa-Michael addition and subsequent intramolecular Mannich condensation.     

Anomalously interacting new extra vector bosons and their first LHC constraints

In this review phenomenological consequences of the Standard Model extension by means of new spin-1 chiral fields with the internal quantum numbers of the electroweak Higgs doublets are summarized. The prospects for resonance production and detection of the chiral vector Z* and W*^± bosons at the LHC energies are considered on the basis of quantitative simulations within the CompHEP/CalcHEP package. The Z* boson can be observed as a Breit-Wigner resonance peak in the invariant dilepton mass distributions in the same way as the well-known extra gauge Z?? bosons. However, the Z* bosons have unique signatures in transverse momentum, angular and pseudorapidity distributions of the final leptons, which allow one to distinguish them from other heavy neutral resonances. In 2010, with 40 pb^?1 of the LHC proton-proton data at the energy 7 TeV, the ATLAS detector was used to search for narrow resonances in the invariant mass spectrum of e ⁺ e ^? and ??⁺??^? final states and high-mass charged states decaying to a charged lepton and a neutrino. No statistically significant excess above the Standard Model expectation was observed. The exclusion mass limits of 1.15 and 1.35 TeV/c ² were obtained for the chiral neutral Z* and charged W* bosons, respectively. These are the first direct limits on the W* and Z* boson production. Based on the above, a novel strategy for the chiral boson search in the LHC dijet data is discussed. For almost all currently considered exotic models the relevant signal is expected in the central dijet rapidity region y _1,2 ? 0 and |y ₁ ? y ₂| ? 0. On the contrary, the chiral bosons do not contribute to this region but produce an excess of dijet events far away from it. In particular, for these bosons the appropriate kinematical restrictions lead to a dip in the centrality ratio distribution over the dijet invariant mass instead of a bump expected in the most exotic models.