Study on the Phase Diagram of CsCl-CeCl3-HCl(11%)-H2O System and the Properties of the Compounds

The equilibrium solubility of CsCl-CeCl3-HCl(11%)-H2O qua-ternary system at 25℃ has been determined by the physicchemical analysis method ,and the phase diagram was plotted, Two new double salts 3CsCl.CeCl3.3H2O and CsCl.CeCl3.4H2O obtained from the complicated system were identified and characterized by XRD,TG-DTA ,DSC,UV and fluorescence spectroscopy, Studies on the fluorescence excitation and emission show that 3CsCl.CeCl3.3H2O and CsCl.CeCl3.4H2O have upconversion luminescence of infrared-visible range,and the upconversion emission intensity increases with the increase of ratio of CeCl3 in CsCl.     

Reactions in a Mixture of CH4 and CO2 under the Aciton of Microwave Discharge at Atmospheric Pressure

Reactions between CH4 and CO2 under the action of continuous microwave discharge at atmospheric pressure were studied in a special homemade reactor,The main products were CO and H2,while acetylene and ethylene were also found in the products.Experimental results show that conversions of CH4 and CO2 could be higher than 90% without the presence of any catalyst,Effects of CO2/CH4 molar ratio and total flow rate of the feed gas on the reaction were also investigated.     

Aquachlorobis(4,4′,4′′‐tri‐tert‐butyl‐2,2′;6′,2′′‐terpyridine‐κ3N)terbium(III) diperchlorate ethanol disolvate

In the title compound, [TbCl(C₂₇H₃₅N₃)₂(H₂O)](ClO₄)₂·2C₂H₆O, the Tb^III ion has a coordination number of eight, composed of two tridentate substituted‐ter­pyridine ligands, a water mol­ecule and a bound Cl^? anion. The first coordination shell can be described as a distorted bicapped trigonal prism. The dihedral angles between pyridine rings belonging to the same tpy ligand range from 5.2 (5) to 16.8 (5)°.     

Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs

Metabolite-sensing mRNAs, or "riboswitches," specifically interact with small ligands and direct expression of the genes involved in their metabolism. Riboswitches contain sensing "aptamer" modules, capable of ligand-induced structural changes, and downstream regions, harboring expression-controlling elements. We report the crystal structures of the add A-riboswitch and xpt G-riboswitch aptamer modules that distinguish between bound adenine and guanine with exquisite specificity and modulate expression of two different sets of genes. The riboswitches form tuning fork-like architectures, in which the prongs are held in parallel through hairpin loop interactions, and the internal bubble zippers up to form the purine binding pocket. The bound purines are held by hydrogen bonding interactions involving conserved nucleotides along their entire periphery. Recognition specificity is associated with Watson-Crick pairing of the encapsulated adenine and guanine ligands with uridine and cytosine, respectively.     

Molecular variations in Th1-specific cell surface gene Tim-3

The family of T-cell immunoglobulin domain and mucin domain (TIM) proteins is identified to be expressed on T cells. A member of Tim family, Tim-3 (T cell immunoglobulin mucin 3) is selectively expressed on the surface of differentiated Th1 cells. Tim-3 might have an important role in the induction of autoimmune diseases by regulating macrophage activation and interacts with Tim-3 ligand to regulate Th1 responses. To determine the variation sites in the coding and promoter region of human Tim-3 gene, we performed variation scanning by direct sequencing using the genomic DNA isolated from the patients with asthma or allergic rhinitis and healthy controls without asthma and allergic rhinitis. We identified four single nucleotide polymorphisms (SNPs) including one novel SNPs (-1541C>T) and two variation sites (-1292_-1289delTAAA and -1282_-1278dupTAAAA) in the coding and promoter region of human Tim-3 gene in both the patients and healthy groups.     

Cytotoxic Constituents from the Stem Bark of Zanthoxylum Pistaciiflorum

Two new esters, methyl 4‐(prenyloxy)dihydrocinnamate and methyl 4‐(geranyloxy)dihydrocinnamate, together with fourteen known compounds have been isolated from the stem bark of Zanthoxylum pistaciiflorum. The structures of two new compounds were determined through spectral analyses. Among the isolates, four compounds exhibited effective cytotoxicities against P‐388 and HT‐29 cell lines in vitro.     

Synthesis of 6,13-Dihydroxyimino-5,12-Dimethyl- 7,14-Dioxo-1,4,8,11-Tetraazacyclotetradeca-4,11-Diene

6,13-Dihydroxyimino-5,12-dimethyl-7,14-dioxo-1,4,8,11-tetraazacyclotetradeca-4,11-diene 2 was prepared by condensation of ethyl α-oximinoacetoacetate with ethylenediamine in tetrahydrofuran at room temperature. Reduction of 2 gave the corresponding 6,13-dihydroxyimino-5,12-dimethyl-7,14-dioxo-1,4,8,11-tetraazacyclotetradecane 3 . Acylation of 2 afforded 6,13-bis(O-acetoxyimino)-5,12-dimethyl-7,14-dioxo-1,4,8,1 l-tetraazacyclotetradeca-4,11-diene 4 . The structures of 2 , 3 and 4 were determined by IR, NMR and mass spectroscopy.     

Aromatization of methane over different Mo-supported catalysts in the absence of oxygen

Both acidity and structure of the support are important factors in converting methane to aromatics. Lower SiO₂/Al₂O₃ ratio seems to favor the aromatization of methane over the Mo/HZSM-5 catalyst. When Pt is added as a modifier the activity of Mo/HZSM-5 catalyst will decrease slightly, but coke formation will enhanced.     

Enhanced fluorescence from o-phthalaldehyde and fluorescamine fluorophores using Triton and β-cyclodextrin

Mexiletine— and lysine hydrochloride—o-phthalaldehyde and mexiletine hydrochloride—, cysteine—, cysteamine—, homocysteine— and lysine hydrochloride—fluorescamine derivatives were subjected to Triton and β-cyclodextrin enhancement treatments. Of several classical fluorescence-enhancing reagents tested (Triton, β-cyclodextrin, sodium dodecyl sulphate, Brij), Triton provided the best results, followed by β-cyclodextrin. Increases in fluorescence emission by a factor of up to about 10 (mexiletine—fluorescamine—Triton X-100) were observed, with a generally negligible influence of the enhancing reagents on the excitation and emission maxima. Fluorescence enhancement by the addition of a suitable reagent solution to the final analyte solution may, in specific instances, enhance the detectability of native or chemically induced fluorophores.