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131.
Carmela Maria Montone Michela Antonelli Anna Laura Capriotti Chiara Cavaliere Giorgia La Barbera Susy Piovesana Aldo Lagan 《Journal of separation science》2019,42(10):1938-1947
An analytical method for determining seleno‐methionine, methyl‐seleno‐cysteine, and seleno‐cystine in wheat bran was developed and validated. Four different extraction procedures were evaluated to simultaneously extract endogenous free and conjugated seleno‐amino acids in wheat bran in order to select the best extraction protocol in terms of seleno amino acid quantitation. The extracted samples were subjected to a clean‐up by a reversed phase/strong cation exchange solid‐phase extraction and analyzed by chiral hydrophilic interaction liquid chromatography‐tandem mass spectrometry. The optimized extraction protocol was employed to validate the methodology. Process efficiency ranged from 58 to 112% and trueness from 73 to 98%. Limit of detection and limit of quantification were lower than 1 ng/g. Four wheat bran samples were analyzed for both total Se and single seleno‐amino acids determination. The results showed that Se‐ seleno‐methyl‐l selenocysteine was the major seleno‐amino acid in wheat bran while seleno‐methionine and seleno‐cysteine were both minor species. 相似文献
132.
Gabriele De Chiara G. Massimo Palma 《International Journal of Theoretical Physics》2008,47(8):2165-2175
In this work we describe the effect of classical and quantum noise on the Berry phase. It is not a topical review article
but rather an overview of our work in this field aiming at giving a simple pictorial intuition of our results. 相似文献
133.
Edoardo Milotti Alessio Del Fabbro Chiara Dalla Pellegrina Roberto Chignola 《Physica A》2008,387(16-17):4204-4214
Experimental measurements on semi-synchronous tumor cell populations show that after a few cell cycles they desynchronize completely, and this desynchronization reflects the intercell variability of cell-cycle duration. It is important to identify the sources of randomness that desynchronize a population of cells living in a homogeneous environment: for example, being able to reduce randomness and induce synchronization would aid in targeting tumor cells with chemotherapy or radiotherapy. Here we describe a statistical approach to the analysis of the desynchronization measurements that is based on minimal modeling hypotheses, and can be derived from simple heuristics. We use the method to analyze existing desynchronization data and to draw conclusions on the randomness of cell growth and proliferation. 相似文献
134.
Tiribilli Chiara Sokolová Romana Giannarelli Stefania Valášek Michal 《Monatshefte für Chemie / Chemical Monthly》2015,146(5):807-812
Monatshefte für Chemie - Chemical Monthly - The electrochemical reduction of diflunisal was studied in dimethyl sulfoxide on static mercury drop electrode. Diflunisal yields one irreversible... 相似文献
135.
Marco Masi Maria Chiara Zonno Alessio Cimmino Pierluigi Reveglia Alexander Berestetskiy Angela Boari 《Natural product research》2018,32(13):1537-1547
Ambrosia artemisiifolia L. is responsible for serious allergies induced on humans. Different approaches for its control were proposed during the COST Action FA1203 “Sustainable management of Ambrosia artemisiifolia in Europe” (SMARTER). Fungal secondary metabolites often show potential herbicidal activity. Three phytotoxins were purified from the fungal culture filtrates of Colletotrichum gloeosporioides, isolated from infected leaves of A. artemisiifolia. They were identified by spectroscopic and chemical methods as colletochlorin A, orcinol and tyrosol (1, 2 and 3). The absolute configuration 6’R to colletochlorin A was assigned for the first time applying the advanced Mosher’s method. When assayed by leaf-puncture on A. artemisiifolia only 1 caused the appearance of large necrosis. The same symptoms were also induced by 1 on ambrosia plantlets associated with plant wilting. On Lemna minor, colletochlorin A caused a clear fronds browning, with a total reduction in chlorophyll content. 相似文献
136.
Silvia Rita Amato Aviva Burnstock Maureen Cross Koen Janssens Francesca Rosi Laura Cartechini Raffaella Fontana Alice Dal Fovo Marco Paolantoni Chiara Grazia Aldo Romani Anne Michelin Christine Andraud Aurélie Tournié Joris Dik 《X射线光谱测定》2019,48(4):282-292
The paintings by Édouard Manet in The Courtauld Gallery Déjeuner sur l'herbe (1863–68), Marguerite de Conflans en Toilette de Bal (1870–1880), Banks of the Seine at Argenteuil (1874), and A Bar at the Folies–Bergère (1882) were investigated for the first time using a range of non-invasive in situ analyses. The aims of the study were to investigate the painting techniques and materials used for this group of works and to critically evaluate the technical evidence derived from the integrated use of imaging techniques and portable spectroscopic methods in this context. The paintings were investigated by means of macro X-ray fluorescence (MA-XRF), reflection spectral imaging, portable UV–Vis–NIR spectroscopy, portable Raman spectroscopy, and reflection FTIR. MA-XRF and reflection spectral imaging allowed visualising elements in the compositions that were not visible using traditional methods of technical study. For example, MA-XRF analysis of Déjeuner sur l'herbe revealed elements of the development of the composition that provided new evidence to consider its relationship to other versions of the composition. The study also highlighted questions about the interpretation of elemental distribution maps and spectral images that did not correspond to the reworking visible in X-radiographs. For example, in A Bar at the Folies–Bergère Manet made numerous changes during painting, which were not clearly visualised with any of the techniques used. The research has wider implications for the study of Impressionist paintings, as the results will support technical studies of works by other artists of the period who used similar materials and painting methods. 相似文献
137.
Marcello Nicoletti Chiara Toniolo Maurizio Bruno Mariem Ben Jemia 《Natural product research》2015,29(3):223-230
The chemical composition of three rockrose Cistus species, Cistus monspeliensis, Cistus libanotis and Cistus villosus, collected in Tunisia, was studied by HPTLC, focusing on the terpenes and phenols constituents. Diterpenes of Cistus are important as the main constituents of the leaf sticky aromatic resin, known as labdanum, which are highly appreciated in perfumery. Polyphenols in the methanolic extracts of each species were identified, quantified as total and as flavonoids and tannins, and tested for antioxidant activity. Diterpenes were evident in C. libanotis and C. monspeliensis, whereas they were practically absent in C. villosus; C. libanotis had higher phenolic amount, whereas antioxidant activities were important, but different according to the following tests: DPPH radical scavenging, conversion of the Fe3+/ferricyanide complex and inhibition of β-carotene bleaching. The reported data confirm the validity of utilisation of Cistus sp. in marketed herbal products, as well as the relevant presence of diterpenes in species actually not used for labdanum production. 相似文献
138.
Dr. Bozheng Sun Dr. Meagan S. Oakley Dr. Kota Yoshida Yanwen Yang Prof. Matteo Tommasini Dr. Chiara Zanchi Dr. Andrea Lucotti Dr. Michael J. Ferguson Dr. Frank Hampel Prof. Mariusz Klobukowski Prof. Rik R. Tykwinski 《Chemistry (Weinheim an der Bergstrasse, Germany)》2022,28(38):e202200616
Cyclic tetraaryl[5]cumulenes ( 1 a–f ) have been synthesized and studied as a function of increasing ring strain. The magnitude of ring strain is approximated by the extent of bending of the cumulenic core as assessed by a combination of X-ray crystallographic analysis and DFT calculations. Trends are observed in 13C NMR, UV-vis, and Raman spectra associated with ring strain, but the effects are small. In particular, the experimental HOMO-LUMO gap is not appreciably affected by bending of the [5]cumulene framework from ca. 174° (λmax=504 nm) in 1 a to ca. 178° (λmax=494 nm) in 1 f . 相似文献
139.
Giulia Marsico Barbara A. Pignataro Marco Masi Antonio Evidente Francesca Casella Maria Chiara Zonno Jun-Hyung Tak Jeffrey R. Bloomquist Stefano Superchi Patrizia Scafato 《Tetrahedron》2018,74(28):3912-3923
The first asymmetric total synthesis of both enantiomers of the natural products colletorin A and colletochlorin A is presented. The proposed methodology is based on the coupling reaction between highly substituted aromatic Gilman cuprates and optically active allyl bromides, in turn obtained by Sharpless asymmetric dihydroxylation. The latter ensured a high degree of regio- and stereocontrol in the enantioselective step of the synthesis. The same synthetic strategy has been also applied for the preparation of differently halogenated synthetic analogues of colletochlorin A in high enantiomeric purity. The enantioselective synthesis of colletorin A and colletochlorin A allows to reliably assign their absolute configuration. Preliminary assessment of their herbicidal and insecticidal properties evidence the possibility to modulate the bioactivity of these compounds, highlighting its dependence on both the absolute stereochemistry and the halogen nature. 相似文献
140.
Bizzarri M Cavaliere C Foglia P Guarino C Samperi R Laganà A 《Analytical and bioanalytical chemistry》2008,391(5):1969-1976
A label-free absolute quantitation method based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
(MALDI-TOF MS) has been developed. This methodology was applied to mouse heart in order to quantify cardiac troponin T (cTnT),
which is considered to be a sensitive marker of heart damage. The cTnT was extracted, isolated by reversed-phase high-performance
liquid chromatography, digested, and analyzed by MALDI-TOF MS. The MS-based quantitation was performed using matrix-matched
calibration curves (due to a matrix effect) of two synthetic peptides, one cTnT-specific peptide and one internal standard
peptide, respectively. Recoveries at three spiking levels ranged from 87–96%, with relative standard deviations of below 10%.
The method detection limit and the method quantitation limit, expressed as the amount of cTnT for the amount of total sarcomeric
protein extract, were 0.03 mg g−1 and 0.15 mg g−1, respectively. This method appears to be accurate and generally suitable for improving absolute protein quantitation. 相似文献